Zobrazeno 1 - 10
of 781
pro vyhledávání: '"F, Helm"'
Publikováno v:
Communications Earth & Environment, Vol 5, Iss 1, Pp 1-12 (2024)
Abstract The energy crisis reshaped energy politics, resulted in energy price surges, increased energy capacity, and large-scale energy-saving campaigns. While an energy demand reduction was observed in Europe, little is known about how the crisis im
Externí odkaz:
https://doaj.org/article/bdbacb91640d479ca8d61c2bde6f8bd0
Autor:
Morgan B. Patrick, Natalie J. Preveza, Shannon E. Kincaid, Gueladouan Setenet, Jennifer R. Abraham, Adam Cummings, Shifa Banani, W. Keith Ray, Richard F. Helm, Sydney Trask, Timothy J. Jarome
Publikováno v:
Brain Research Bulletin, Vol 215, Iss , Pp 111015- (2024)
The ubiquitin-proteasome system (UPS) controls the majority of protein degradation in cells and dysregulation of the UPS has been implicated in the pathophysiology of numerous neurodegenerative disorders, including Alzheimer’s disease. Further, str
Externí odkaz:
https://doaj.org/article/e486658b1c924010a42b05f52996e968
Autor:
Cristina Sarasa-Buisan, Mercedes Nieves-Morión, Sergio Arévalo, Richard F. Helm, Emma Sevilla, Ignacio Luque, María F. Fillat
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Microbial extracellular proteins and metabolites provide valuable information concerning how microbes adapt to changing environments. In cyanobacteria, dynamic acclimation strategies involve a variety of regulatory mechanisms, being ferric u
Externí odkaz:
https://doaj.org/article/74d6e66454a3473581fbe8c500163028
Autor:
Kayla Farrell, Aubrey Auerbach, Catherine Liu, Kiley Martin, Myasia Pareno, W. Keith Ray, Richard F. Helm, Fernando Biase, Timothy J. Jarome
Publikováno v:
Biology of Sex Differences, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Background Sex differences have been observed in several brain regions for the molecular mechanisms involved in baseline (resting) and memory-related processes. The ubiquitin proteasome system (UPS) is a major protein degradation pathway in
Externí odkaz:
https://doaj.org/article/a5310153294e43739689cf12b644a0a3
Autor:
Yang Song, Didier Mena-Aguilar, Connor L. Brown, William J. Rhoads, Richard F. Helm, Amy Pruden, Marc A. Edwards
Publikováno v:
Pathogens, Vol 13, Iss 7, p 563 (2024)
Cu is an antimicrobial that is commonly applied to premise (i.e., building) plumbing systems for Legionella control, but the precise mechanisms of inactivation are not well defined. Here, we applied a suite of viability assays and mass spectrometry-b
Externí odkaz:
https://doaj.org/article/6557964de6f247fd8301a0d47d167e37
Autor:
Hannah H. Nam, BA, Abigail Washington, BA, Melissa Butt, DrPH, Steven Maczuga, MS, Daniel Guck, DO, Jeff D. Yanosky, ScD, MS, Matthew F. Helm, MD
Publikováno v:
JAAD International, Vol 9, Iss , Pp 30-32 (2022)
Externí odkaz:
https://doaj.org/article/ea93f50577ee4dbcbedb3f6bd29b802b
Publikováno v:
JAAD Case Reports, Vol 12, Iss , Pp 5-7 (2021)
Externí odkaz:
https://doaj.org/article/f321003d4a7a4cb3b8691d30ab1150f8
Autor:
Ling Wu, Zerui Wang, Shradha Lad, Nailya Gilyazova, Darren T. Dougharty, Madeleine Marcus, Frances Henderson, W. Keith Ray, Sandra Siedlak, Jianyong Li, Richard F. Helm, Xiongwei Zhu, George S. Bloom, Shih-Hsiu J. Wang, Wen-Quan Zou, Bin Xu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Tau aggregates are present in multiple neurodegenerative diseases known as “tauopathies,” including Alzheimer’s disease, Pick’s disease, progressive supranuclear palsy, and corticobasal degeneration. Such misfolded tau aggregates are therefor
Externí odkaz:
https://doaj.org/article/b63cc166b1c74a4a907cad6f0b99dd9b
Autor:
Matthew F. Helm, MD, Alexa B. Kimball, MD, MPH, Melissa Butt, MPH, Heather Stuckey, MEd, DEd, Heather Costigan, BS, Kanade Shinkai, MD, PhD, Arielle R. Nagler, MD
Publikováno v:
International Journal of Women's Dermatology, Vol 8, Iss 1, p e013 (2022)
Background:. Burnout is increasing in all fields of medicine, including dermatology. The coronavirus disease 2019 (COVID-19) pandemic presented new and additional challenges for dermatologists. Objective:. Dermatologists of different ages, areas of e
Externí odkaz:
https://doaj.org/article/74f3edda3ddd4313abc7b2bd30dcecdb
Autor:
Kayla Farrell, Madeline Musaus, Shaghayegh Navabpour, Kiley Martin, W. Keith Ray, Richard F. Helm, Timothy J. Jarome
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Ubiquitin-proteasome mediated protein degradation has been widely implicated in fear memory formation in the amygdala. However, to date, the protein targets of the proteasome remain largely unknown, limiting our understanding of the functional signif
Externí odkaz:
https://doaj.org/article/8a909226cb1b417d9bdd8914a309ccb7