Zobrazeno 1 - 10
of 1 250
pro vyhledávání: '"F, Harder"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-6 (2023)
Abstract Observing proteins as they perform their tasks has largely remained elusive, which has left our understanding of protein function fundamentally incomplete. To enable such observations, we have recently proposed a technique that improves the
Externí odkaz:
https://doaj.org/article/a8564442faf94bcbabaafe60cd6d1f01
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
We have recently introduced a novel approach to time-resolved cryo-electron microscopy (cryo-EM) that affords microsecond time resolution. It involves melting a cryo sample with a laser beam to allow dynamics of the embedded particles to occur. Once
Externí odkaz:
https://doaj.org/article/37d46117e88647679c49587b98dc3f8d
Publikováno v:
Structural Dynamics, Vol 8, Iss 5, Pp 054302-054302-8 (2021)
The dynamics of proteins that are associated with their function typically occur on the microsecond timescale, orders of magnitude faster than the time resolution of cryo-electron microscopy. We have recently introduced a novel approach to time-resol
Externí odkaz:
https://doaj.org/article/7d439a0e30824bfa8d2112289ff7f866
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
We have recently introduced a microsecond time-resolved version of cryo-electron microscopy (cryo-EM) to enable the observation of the fast conformational motions of proteins. Our technique involves locally melting a cryo sample with a laser beam to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee23e85ddabf6e6f6e2ce9155601866a
https://doi.org/10.1101/2023.02.20.529238
https://doi.org/10.1101/2023.02.20.529238
Autor:
Friedrich Kallinowski, F. Harder, D. Gutjahr, R. Raschidi, T. G. Silva, M. Vollmer, Regine Nessel
Publikováno v:
Frontiers in Surgery, Vol 4 (2018)
Recurrences are frequently observed after ventral hernia repair. Based on clinical data, the mesh–defect area ratio (MDAR) can lead to lower recurrence rates. Using dynamic intermittent strain (DIS) in a pig tissue model, MDAR can be modified to gi
Externí odkaz:
https://doaj.org/article/db8c56e8b8dd4c3f80ad0e613c3eda95
Publikováno v:
Acta Crystallographica Section D: Structural Biology
We have recently introduced a novel approach to time-resolved cryo-electron microscopy (cryo-EM) that involves melting a cryo sample with a laser beam to allow protein dynamics to briefly occur in liquid, before trapping the particles in their transi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2573dc46442645e81dc61392865ac578
Publikováno v:
Microscopy and Microanalysis. 27:17-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::825d004f17f5dd7337d296a32a400e20
https://doi.org/10.1017/s1431927621013088
https://doi.org/10.1017/s1431927621013088
Publikováno v:
Chemical Physics Letters
Proteins typically undergo conformational dynamics on the microsecond to millisecond timescale as they perform their function, which is much faster than the time-resolution of cryo-electron microscopy and has thus prevented real-time observations. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb7734ba31fdc466521d182361f3c75
Publikováno v:
Swiss Medical Weekly, Vol 131, Iss 0708 (2001)
Externí odkaz:
https://doaj.org/article/b936bd6692b44084bb171a8f74307ecd