Membrane Rafts Segregate Pro- from Anti-Apoptotic Insulin-Like Growth Factor-I Receptor Signaling in Colon Carcinoma Cells Stimulated by Members of the Tumor Necrosis Factor Superfamily

Autor: M Remacle-Bonnet, Jacques Marvaldi, Gilbert Baillat, F Garrouste, Frédéric André, Gilbert Pommier

Publikováno v: The American Journal of Pathology. 167:761-773

In the tumor microenvironment, autocrine/paracrine loops of insulin-like growth factors (IGFs) contribute to cancer cell survival. However, we report here that IGF-I can send contradictory signals that interfere with cell death induced by different l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7902c9bb9e9be445f9e01c0b57a72eec
https://doi.org/10.1016/s0002-9440(10)62049-4

Up-Regulation of Insulin/Insulin-Like Growth Factor-I Hybrid Receptors during Differentiation of HT29-D4 Human Colonic Carcinoma Cells1

Autor: Gilbert Pommier, F Garrouste, Jacques Marvaldi, M Remacle-Bonnet, Maxime Lehmann

Publikováno v: Endocrinology. 138:2021-2032

To assess the autocrine function of insulin-like growth factor II (IGF-II) in the balance of proliferation and differentiation in HT29-D4 human colonic cancer cells, we studied the expression of IGF-I receptors (IGF-IR) and insulin receptors (IR) in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d5f7cca1cd557115da320b64f42aab27
https://doi.org/10.1210/endo.138.5.5100

Gα(q/11)-coupled P2Y 2 nucleotide receptor inhibits human keratinocyte spreading and migration

Autor: Julie Milanini, Jean-Claude Hubaud, Fabrice Parat, Jun Takasaki, F Garrouste, Salma Taboubi, Hervé Kovacic, Maxime Lehmann, Gilbert Pommier, Estelle Delamarre

Publikováno v: FASEB Journal
FASEB Journal, Federation of American Society of Experimental Biology, 2007, 21 (14), pp.4047-4058. ⟨10.1096/fj.06-7476com⟩
FASEB Journal, 2007, 21 (14), pp.4047-4058. ⟨10.1096/fj.06-7476com⟩

International audience; Reepithelialization is a critical step in wound healing. It is initiated by keratinocyte migration at the wound edges. After wounding, extracellular nucleotides are released by keratinocytes and other skin cells. Here, we repo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::340fcda91b2127a1cefc8eecc63898ae
https://hal-amu.archives-ouvertes.fr/hal-01744755

Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism

Autor: F Garrouste, M Remacle-Bonnet, Gilbert Pommier, C Fauriat, J Marvaldi, José Luis

Publikováno v: Cell death and differentiation. 9(7)

We have previously established that insulin-like growth factor (IGF)-I, -II and insulin exert a strong protective effect against tumor necrosis factor-alpha (TNF)-induced apoptosis in interferon-gamma (IFN)-sensitized HT29-D4 human colon carcinoma ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56fbacb5ffe7937740a4076e3ef24ca
https://pubmed.ncbi.nlm.nih.gov/12058282

Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) proteolysis in patients with colorectal cancer: possible association with the metastatic potential of the tumor

Autor: Marjorie Baciuchka, Roger Favre, F Garrouste, M Remacle-Bonnet, Bernard Sastre, Gilbert Pommier

Publikováno v: International journal of cancer. 79(5)

The limited proteolysis of insulin-like growth factor (IGF)-binding protein (IGFBP)-3 is a key event in the regulation of endocrine bioavailability of IGFs. Here, we investigated IGFBP-3 and IGFBP-3 proteolysis in serum from patients with colorectal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e57ddddf5fe46c445413e315e1a51448
https://pubmed.ncbi.nlm.nih.gov/9761113