Zobrazeno 1 - 10
of 248
pro vyhledávání: '"F, Frye"'
Autor:
John S. Markowitz, Ludmila De Faria, Qingchen Zhang, Philip W. Melchert, Reginald F. Frye, Brandon O. Klee, Yuli Qian
Publikováno v:
Medical Cannabis and Cannabinoids, Vol 5, Iss 1, Pp 199-206 (2022)
Introduction: Cannabidiol (CBD) is a widely utilized nonpsychoactive cannabinoid available as an over-the-counter supplement, a component of medical cannabis, and a prescriptive treatment of childhood epilepsies. In vitro studies suggest CBD may inhi
Externí odkaz:
https://doaj.org/article/b6cc5d042a37487ebd1d16fc30802139
Autor:
Scott A. Mosley, Sarah Kim, Nihal El Rouby, Karthik Lingineni, Valvanera Vozmediano Esteban, Yan Gong, Yiqing Chen, David Estores, Kairui Feng, Hyewon Kim, Minori Kinjo, Taimour Langaee, Zhichuan Li, Siegfried O. F. Schmidt, Julie A. Johnson, Reginald F. Frye, Lanyan (Lucy) Fang, Liang Zhao, Philip F. Binkley, Stephan Schmidt, Larisa H. Cavallari
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 7, Pp 1764-1775 (2022)
Abstract There are limited comparison data throughout the dosing interval for generic versus brand metoprolol extended‐release (ER) tablets. We compared the pharmacokinetics (PKs) and pharmacodynamics of brand name versus two generic formulations (
Externí odkaz:
https://doaj.org/article/85721359ad2249029647b4bf510af13c
Autor:
Ahmed A. Albassam, Reginald F. Frye
Publikováno v:
Saudi Pharmaceutical Journal, Vol 27, Iss 3, Pp 406-412 (2019)
Pterostilbene is a natural polyphenol compound found in small berries that is related to resveratrol, but has better bioavailability and a longer half-life. The purpose of this study was to assess the potential inhibitory effect of pterostilbene on i
Externí odkaz:
https://doaj.org/article/9a339326009c408391b4e8fb922c2e20
A Genetic Score Associates With Pioglitazone Response in Patients With Non-alcoholic Steatohepatitis
Autor:
Marina Kawaguchi-Suzuki, Kenneth Cusi, Fernando Bril, Yan Gong, Taimour Langaee, Reginald F. Frye
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Pioglitazone is used effectively to treat non-alcoholic steatohepatitis (NASH), but there is marked variability in response. This study examined whether genetic variation contributes to pioglitazone response variability in patients with NASH. This ge
Externí odkaz:
https://doaj.org/article/925e93421a98439e92973a7e61b7a9af
Autor:
Mohamed H. Shahin, Yan Gong, Reginald F. Frye, Daniel M. Rotroff, Amber L. Beitelshees, Rebecca A. Baillie, Arlene B. Chapman, John G. Gums, Stephen T. Turner, Eric Boerwinkle, Alison Motsinger‐Reif, Oliver Fiehn, Rhonda M. Cooper‐DeHoff, Xianlin Han, Rima Kaddurah‐Daouk, Julie A. Johnson
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 1 (2018)
BackgroundAlthough hydrochlorothiazide (HCTZ) is a well‐established first‐line antihypertensive in the United States,
Externí odkaz:
https://doaj.org/article/fe620dad6620414db7224233285d8236
Autor:
Kristin Wiisanen, Yan Gong, Caitrin W. McDonough, Julie A. Johnson, Amanda R. Elsey, Larisa H. Cavallari, Taimour Y. Langaee, Meghan J. Arwood, Reginald F. Frye
Publikováno v:
JACCP: JOURNAL OF THE AMERICAN COLLEGE OF CLINICAL PHARMACY. 4:343-351
Autor:
Zhichuan Li, Danxin Wang, Liang Zhao, Scott A. Mosley, Yan Gong, Rhonda M. Cooper-DeHoff, Minori Kinjo, Reginald F. Frye, Cameron D. Thomas, Taimour Y. Langaee, Arlene B. Chapman, Sarah Kim, Hyewon Kim, Larisa H. Cavallari, Issam Hamadeh, John G. Gums, David S. Estores, Siegfried Schmidt, Lanyan Fang, Julie A. Johnson, Stephan Schmidt, Nihal El Rouby, Karthik Lingineni, Kairui Feng, Philip F. Binkley
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
Recent CYP2D6 phenotype standardization efforts by CYP2D6 activity score (AS) are based on limited pharmacokinetic (PK) and pharmacodynamic (PD) data. Using data from two independent clinical trials of metoprolol, we compared metoprolol PK and PD acr
Autor:
Stacy A. Voils, Laurence M. Solberg, Sonal Singh, Reginald F. Frye, Bethany R. Shoulders, Timothy J. Garrett
Publikováno v:
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy. 40:500-506
Introduction In intensive care unit (ICU) patients, delirium is frequent, occurs early in ICU admission, and is associated with poor outcomes. Risk models based on clinical factors have shown variable performance in terms of predictive ability. Ident
Autor:
Meghan J. Arwood, Caitrin Rowe McDonough, Larisa H. Cavallari, Amanda R. Elsey, Reginald F. Frye, Yan Gong, Julie A. Johnson, Kristin W. Weitzel, Taimour Langaee
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 46-46 (2017)
OBJECTIVES/SPECIFIC AIMS: Compare effectiveness of a patient case-based, interactive teaching approach that included optional student genotyping with traditional didactic teaching strategies for increasing students’ knowledge and ability to effecti
Externí odkaz:
https://doaj.org/article/f7694bb5b1104c8ba94182b8a72fd9fb
Autor:
Ryan M. Kemper, Heemaja Mewada, Jeffrey S. Damrauer, Brian Hardy, Stephen F. Frye, Kenneth H. Pearce, Jesse Raab, William Y. Kim, Daniel James Crona
Publikováno v:
Cancer Research. 82:3267-3267
Background: Bladder cancer (BC) is a common and deadly disease. Inactivating ARID1A mutations occur in up to 30% of metastatic BC tumors, making it the most commonly mutated epigenetic gene and the 4th most commonly mutated gene overall in BC. ARID1A