The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells

Autor: M. Jacoupy, E. Hamon-Keromen, A. Ordureau, Z. Erpapazoglou, F. Coge, J.-C. Corvol, O. Nosjean, C. Mannoury la Cour, M. J. Millan, J. A. Boutin, J. W. Harper, A. Brice, D. Guedin, C. A. Gautier, O. Corti

Publikováno v: Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)

Abstract Most of over a thousand mitochondrial proteins are encoded by nuclear genes and must be imported from the cytosol. Little is known about the cytosolic events regulating mitochondrial protein import, partly due to the lack of appropriate tool

Externí odkaz: https://doaj.org/article/e3de579c73004127a500e989a78a21a9

Parkin maintains mitochondrial levels of the protective Parkinson’s disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10

Autor: Andrew J. Lees, D. Guedin, Giulia Bertolin, H Ardila-Osorio, Alexis Brice, T Saint Georges, Sabine Traver, MP Muriel, F. Coge, Rosa Ferrando-Miguel, Clement A. Gautier, H Takahashi, Maxime Jacoupy, Olga Corti, Karl Grenier, Edward A. Fon

Publikováno v: Cell Death and Differentiation
Cell Death and Differentiation, 2015, 22 (10), pp.1563-1576. ⟨10.1038/cdd.2014.224⟩
Cell Death and Differentiation, Nature Publishing Group, 2015, 22 (10), pp.1563-1576. ⟨10.1038/cdd.2014.224⟩

International audience; Mutations of the PARK2 and PINK1 genes, encoding the cytosolic E3 ubiquitin-protein ligase Parkin and the mitochondrial serine/threonine kinase PINK1, respectively, cause autosomal recessive early-onset Parkinson's disease (PD

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214f3c8a20fae44fafd290d38614936a
https://hal.umontpellier.fr/hal-03123818

Endothelin-1 pathway in human alveolar epithelial cell line A549 and human umbilical vein endothelial cells

Autor: I, Deprez-Roy, F, Coge, L, Bertry, J P, Galizzi, M, Feletou, P M, Vanhoutte, E, Canet

Publikováno v: Acta pharmacologica Sinica. 21(6)

This study was designed to characterize the endothelin pathway in an immortalized human adenocarcinoma-derived alveolar epithelial cell line (A549) and human umbilical vein endothelial cell line (HUVEC).The release of ET-1 and big-ET-1 was measured i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e165e567239bdb714bde4f0fbd1d6a05
https://pubmed.ncbi.nlm.nih.gov/11360683

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