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Akademický článek
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NF-κB p50/RelA and c-Rel-containing dimers: opposite regulators of neuron vulnerability to ischaemia
Autor:
Markus Schwaninger, Manuela Alghisi, Ilenia Sarnico, Marina Pizzi, Ioana Inta, Annamaria Lanzillotta, Marina Benarese, F. Boroni, Leontino Battistin, PierFranco Spano
Publikováno v:
Journal of Neurochemistry. 108:475-485
Diverse nuclear factor-kappaB subunits mediate opposite effects of extracellular signals on neuron survival. While RelA is activated by neurotoxic agents, c-Rel drives neuroprotective effects. In brain ischaemia RelA and p50 factors rapidly activate,
Autor:
I-Chia Huang, Jonathan M. Levenson, Regula Egli, Marina Pizzi, J. David Sweatt, Priyanka Desai, F. Boroni, PierFranco Spano, Olivia Fitch, Hsiou-Chi Liou, Lauren Malone, Hyung Jin Ahn, Kenneth J. O’Riordan
Publikováno v:
The Journal of Neuroscience. 26:4870-4879
An increasing amount of evidence suggests that the family of nuclear factor κB (NF-κB) transcription factors plays an important role in synaptic plasticity and long-term memory formation. The present study investigated the regulation of NF-κB fami
Autor:
Marina Benarese, PierFranco Spano, Marina Pizzi, F. Boroni, Alessandra Valerio, Valentina Ghisi, Ilenia Sarnico, Laura Grazia Bresciani, Giuseppe Borsani, Marina Ferrario
Publikováno v:
European Journal of Neuroscience. 23:1711-1720
Beta-amyloid (Abeta) peptides are key proteins in the pathophysiology of Alzheimer's disease (AD). While Abeta42 aggregates very rapidly to form early diffuse plaques, supplemental Abeta40 deposition is required to form mature neuritic plaques. We he
Autor:
F. Boroni, Francesca Goffi, Andrea Bianchetti, Alessandra Valerio, Marina Pizzi, PierFranco Spano, Costantinos Moraitis, Ilenia Sarnico, Marina Benarese
Publikováno v:
European Journal of Neuroscience. 16:2342-2350
The present study demonstrates that human SK-N-SH neuroblastoma cells, differentiated by retinoic acid (RA), express functional NMDA receptors and become vulnerable to glutamate toxicity. During exposure to RA, SK-N-SH cells switched from non-neurona
Autor:
Hsiou-Chi Liou, Francesca Goffi, Marina Pizzi, Marina Benarese, Scott Perkins, PierFranco Spano, F. Boroni
Publikováno v:
Journal of Biological Chemistry. 277:20717-20723
The nuclear transcription factors NF-kappaB/Rel have been shown to function as key regulators of either cell death or survival in neuronal cells. Here, we investigated whether selective activation of diverse NF-kappaB/Rel family members might lead to
Autor:
O. Consolandi, P. F. Spano, Maurizio Memo, Paola Galli, F. Boroni, M. Benarese, Marina Pizzi, S. Gavazova
Publikováno v:
European Neuropsychopharmacology. 6:S4-10
Autor:
F. Boroni, Alessandro Barbon, Mario Rosario Buffelli, Giorgio Brunelli, Michele Ettorre, Maura Francolini, PierFranco Spano, Francesco Clementi, Annamaria Lanzillotta, Marina Pizzi, Cristina Baiguera, Bruno Guarneri, Luca La Via, Sergio Barlati, Ilaria Cambianica
After denervation of adult rat abdominal muscles, the postsynaptic apparatus of neuromuscular junctions (NMJs) retains its original architecture and clustering of acetylcholine receptors (AChRs). When descending fibers of the spinal cord are surgical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84001621c3fbea0c94ba019f3659d0d6
http://hdl.handle.net/11562/335943
http://hdl.handle.net/11562/335943
Autor:
Alessandra Valerio, PierFranco Spano, Giuseppe Faraco, Marta Dossena, Paola Bertolotti, Ilenia Sarnico, Enzo Nisoli, Andrea Frontini, Alberto Chiarugi, Hsiou-Chi Liou, Marina Pizzi, Michele O. Carruba, F. Boroni, Maria Grazia De Simoni, Antonio Giordano
Background and Purpose— Leptin is an adipose hormone endowed with angiopoietic, neurotrophic, and neuroprotective properties. We tested the hypothesis that leptin might act as an endogenous mediator of recovery after ischemic stroke and investigate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e3a87b21b6119aa59a793123dcc6060
http://hdl.handle.net/11379/28242
http://hdl.handle.net/11379/28242