Zobrazeno 1 - 10
of 67
pro vyhledávání: '"F, Beslot"'
Publikováno v:
Journal of Pharmacy and Pharmacology. 43:504-509
The cardiovascular effects of (±)-nebivolol, a potent β1-adrenoceptor antagonist, and its enantiomers, (+)-nebivolol (SRRR) and (–)-nebivolol (RSSS) in normotensive anaesthetized rats, have been investigated using metoprolol as a reference substa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b351099ee7b319404f88e2a81a026608
https://doi.org/10.1111/j.2042-7158.1991.tb03523.x
https://doi.org/10.1111/j.2042-7158.1991.tb03523.x
Autor:
N, Inguimbert, H, Poras, H, Dhotel, F, Beslot, E, Scalbert, C, Bennejean, P, Renard, M-C, Fournié-Zaluski, B-P, Roques
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 63(2)
Three zinc metallopeptidases are implicated in the regulation of fluid homeostasis and vascular tone and represent interesting targets for the treatment of chronic heart failure. We have previously reported the synthesis of a triple inhibitor able to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::36c395e18d08739b50d8d33841937ebe
https://pubmed.ncbi.nlm.nih.gov/15009531
https://pubmed.ncbi.nlm.nih.gov/15009531
Autor:
E T, Tzavara, E, Valjent, C, Firmo, M, Mas, F, Beslot, N, Defer, B P, Roques, J, Hanoune, R, Maldonado
Publikováno v:
The European journal of neuroscience. 12(3)
Region-specific up-regulation of the cyclic AMP pathway is considered an important molecular mechanism in the origin of the somatic manifestations of the withdrawal syndrome to known drugs of abuse. Nevertheless, the existence of a withdrawal syndrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0a5687d8b2a35d3821bd2d9d4c70f5cf
https://pubmed.ncbi.nlm.nih.gov/10762335
https://pubmed.ncbi.nlm.nih.gov/10762335
Publikováno v:
The European journal of neuroscience. 12(2)
CB1 cannabinoid receptors are widely distributed in the central nervous system where they mediate most of the cannabinoid-induced responses. Here we have evaluated the interactions between the CB1 cannabinoid receptors and the endogenous opioid syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b2b1617103f2a53bf70b17d9e09e8cbd
https://pubmed.ncbi.nlm.nih.gov/10712632
https://pubmed.ncbi.nlm.nih.gov/10712632
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 278(2)
The vasoconstrictor angiotensin II and atrial natriuretic peptide (ANP) are oppositely involved in the development of heart failure, as modeled by myocardial infarction (MI) in rats. MI is a model also characterized by sodium retention despite the el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::50397a7c87877433c6865c1c9631b6f3
https://pubmed.ncbi.nlm.nih.gov/8768706
https://pubmed.ncbi.nlm.nih.gov/8768706
Publikováno v:
General pharmacology. 23(4)
1. The effect of several adrenoceptor agonists and antagonists on the spontaneous and stimulus-evoked release of [3H]noradrenaline was studied in rat isolated portal vein. 2. Yohimbine (10(-6)M) increased the stimulus-evoked [3H]noradrenaline efflux.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fb9db74370210333989c3b26055089
https://pubmed.ncbi.nlm.nih.gov/1356878
https://pubmed.ncbi.nlm.nih.gov/1356878
Functional modulatory mechanism of NA release by HT1-receptors and α2 and β2-adrenoceptors has been observed in vivo. The relative potencies of these inhibitory and facilitatory mechanisms can be modified using selective antagonists, which evidence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e934fd05d628aa8f4d7cd738a2561a
https://doi.org/10.1016/b978-0-08-041165-1.50014-4
https://doi.org/10.1016/b978-0-08-041165-1.50014-4
Publikováno v:
European Journal of Pharmacology. 183:2225-2226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30f84f1aaea780ed1c9d881d5c2bdc24
https://doi.org/10.1016/0014-2999(90)93760-n
https://doi.org/10.1016/0014-2999(90)93760-n
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 82:75-79
Acute i.v. administration of 15 mg/kg acebutolol in normotensive (WKY), Okamoto (SHR) and Okamoto stroke-prone (SHR-SP) awake rats resulted in weak effects on blood pressure and in bradycardia more marked in SHR-SP. Thirty minutes after i.v. administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d348e5134226927530e5c11c1161e11
https://doi.org/10.1016/0742-8413(85)90212-9
https://doi.org/10.1016/0742-8413(85)90212-9
Publikováno v:
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology. 87:83-86
1. Tissue distribution of acebutolol was studied in 33-week-old nonnotensive (WKY) and Okamoto stroke-prone (SHR-SP) rats, 30 min after an i.v. administration, by using 14 C-acebutolol. 2. Plasma level of acebutolol was higher in WKY than in SHR-SP.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32bb69c82c0752eaa2ceb5c57d8d1cb
https://doi.org/10.1016/0742-8413(87)90186-1
https://doi.org/10.1016/0742-8413(87)90186-1