Escleromixedema y síndrome dermato-neuro: buena respuesta al tratamiento con glucocorticoides e inmunoglobulinas endovenosas

Autor: Carlos Ferrándiz, R.M. Guinovart, Isabel Bielsa, F. Benvenutti

Publikováno v: Actas Dermo-Sifiliográficas. 103:317-320

Resumen El escleromixedema es una enfermedad potencialmente grave que puede asociarse a complicaciones sistemicas diversas, entre las que se encuentran las que involucran al sistema nervioso central, siendo el sindrome dermato-neuro una de las mas in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b113914e6787eed0f387d0f91b50fd56
https://doi.org/10.1016/j.ad.2011.04.015

[Good response of scleromyxedema and dermato-neuro syndrome to treatment with intravenous immunoglobulins]

Autor: I, Bielsa, F, Benvenutti, R M, Guinovart, C, Ferrándiz

Publikováno v: Actas dermo-sifiliograficas. 103(4)

Scleromyxedema is a potentially serious disease that can have various systemic complications. One of the most frequent forms of central nervous system involvement is dermato-neuro syndrome. High-dose intravenous immunoglobulins are among the drug tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f15175ece6c705f9a33978ae32edd4fa
https://pubmed.ncbi.nlm.nih.gov/21917233

IRAP+ endosomes restrict TLR9 activation and signaling

Autor: Bénédicte Manoury, Aimé Cézaire Adiko, François-Xavier Mauvais, Sophia Maschalidi, Mariacristina De Luca, Mira Tohme, Luiz Ricardo Vasconcellos, Meriem Garfa-Traore, Joel Babdor, Delphyne Descamps, Michel Chignard, Loredana Saveanu, Melanie M. Brinkmann, Irini Evnouchidou

Publikováno v: Nature Immunology
Nature Immunology, Nature Publishing Group, 2017, 18 (5), pp.509-518. ⟨10.1038/ni.3711⟩
Nature Immunology, Nature Publishing Group, 2017, 18 (5), pp.509-518. 〈10.1038/ni.3711〉
Nature Immunology, 2017, 18 (5), pp.509-518. ⟨10.1038/ni.3711⟩

International audience; The retention of intracellular Toll-like receptors (TLRs) in the endoplasmic reticulum prevents their activation under basal conditions. TLR9 is activated by sensing ligands in specific endosomal-lysosomal compartments. Here w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f62ea0950d4da5d95646be15d00a50
https://hal.archives-ouvertes.fr/hal-03103680