Deciphering the therapeutic potential of trimetazidine in rheumatoid arthritis via targeting mi-RNA128a, TLR4 signaling pathway, and adenosine-induced FADD-microvesicular shedding: In vivo and in silico study.

Autor: Omran E; Department of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Alzahrani AR; Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Ezzat SF; Department of Histology and Cell Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Ellithy G; Department of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Tarek M; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt., Khairy E; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt.; Department of Clinical Biochemistry, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia., Ghit MM; Department of Rheumatology and Rehabilitation, Faculty of Medicine, Al-Azhar University, Cairo, Egypt., Elgeushy A; Orthopedic Department, Faculty of Medicine, Alazhar University Hospitals, Cairo, Egypt., Ibrahim Al-Hazani TM; Biology Department, College of Science and Humanities, Prince Sattam Bin Abdulaziz University, Al-Kharj, Saudi Arabia., Aziz Ibrahim IA; Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Falemban AH; Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Bamagous GA; Department of Pharmacology and Toxicology, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia., Elhawary NA; Department of Medical Genetics, College of Medicine, Umm Al-Qura University, Mecca, Saudi Arabia., Jaremko M; Smart-Health Initiative and Red Sea Research Center, Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia., Saied EM; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt.; Institute for Chemistry, Humboldt Universität zu Berlin, Berlin, Germany., Mohamed DI; Department of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Publikováno v: Frontiers in pharmacology [Front Pharmacol] 2024 Jun 11; Vol. 15, pp. 1406939. Date of Electronic Publication: 2024 Jun 11 (Print Publication: 2024).

Vitamin D3 Prevents the Deleterious Effects of Testicular Torsion on Testis by Targeting miRNA-145 and ADAM17: In Silico and In Vivo Study.

Autor: Mohamed DI; Department of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt., Abou-Bakr DA; Department of Physiology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt., Ezzat SF; Department of Histology and Cell Biology, Faculty of Medicine, Ain Shams University, Cairo 11566, Egypt., El-Kareem HFA; Zoology Department, Faculty of Science, Ain Shams University, Cairo 11566, Egypt., Nahas HHA; Zoology Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt., Saad HA; Department of Chemistry, College of Science, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia., Mehana AE; Zoology Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt., Saied EM; Chemistry Department, Faculty of Science, Suez Canal University, Ismailia 41522, Egypt.; Institute for Chemistry, Humboldt Universität zu Berlin, Brook-Taylor-Str. 2, 12489 Berlin, Germany.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2021 Nov 25; Vol. 14 (12). Date of Electronic Publication: 2021 Nov 25.

Exenatide promotes cardiac lncRNAs HOX transcript antisense RNA (HOTAIR) in Wistar rats with liver cirrhosis; a novel role of GLP-1 receptor agonists in cirrhotic cardiomyopathy.

Autor: El-Kharashi OA; Department of Clinical Pharmacology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address: omnyah2011@gmail.com., Mohamed DI; Department of Clinical Pharmacology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address: doaapharma@yahoo.com., Khairy E; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address: dr_emankhairy@yahoo.co., Ezzat SF; Department of Histology and Cell Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address: samarezzatali@yahoo.com., Zaki WS; Department of Medical Biochemistry and Molecular Biology, Faculty of Medicine, Ain Shams University, Cairo, Egypt. Electronic address: dr.ws.biochemistry@gmail.com.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2019 Jul 15; Vol. 855, pp. 294-304. Date of Electronic Publication: 2019 May 14.