Zobrazeno 1 - 10 of 70 pro vyhledávání: '"Ezio Carboni"'
1
Akademický článek
BDNF Alterations in Brain Areas and the Neurocircuitry Involved in the Antidepressant Effects of Ketamine in Animal Models, Suggest the Existence of a Primary Circuit of Depression
Autor: Ezio Carboni, Anna R. Carta
Publikováno v: Journal of Integrative Neuroscience, Vol 21, Iss 5, p 144 (2022)
Major depressive disorder is one of the primary causes of disability and disease worldwide. The therapy of depression is prevalently based on monoamine reuptake blockers; consequently, investigations aimed to clarify the aetiology of depression have
Externí odkaz: https://doaj.org/article/f98ca508ddf64749b032654e64830f77
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2
Akademický článek
The Intranigral Infusion of Human-Alpha Synuclein Oligomers Induces a Cognitive Impairment in Rats Associated with Changes in Neuronal Firing and Neuroinflammation in the Anterior Cingulate Cortex
Autor: Maria Francesca Palmas, Michela Etzi, Augusta Pisanu, Chiara Camoglio, Claudia Sagheddu, Michele Santoni, Maria Francesca Manchinu, Mauro Pala, Giuliana Fusco, Alfonso De Simone, Luca Picci, Giovanna Mulas, Saturnino Spiga, Maria Scherma, Paola Fadda, Marco Pistis, Nicola Simola, Ezio Carboni, Anna R. Carta
Publikováno v: Cells, Vol 11, Iss 17, p 2628 (2022)
Parkinson’s disease (PD) is a complex pathology causing a plethora of non-motor symptoms besides classical motor impairments, including cognitive disturbances. Recent studies in the PD human brain have reported microgliosis in limbic and neocortica
Externí odkaz: https://doaj.org/article/3eedc67be715406cbd276027691c9ffd
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3
Akademický článek
Repurposing Ketamine in Depression and Related Disorders: Can This Enigmatic Drug Achieve Success?
Autor: Ezio Carboni, Anna R. Carta, Elena Carboni, Antonello Novelli
Publikováno v: Frontiers in Neuroscience, Vol 15 (2021)
Repurposing ketamine in the therapy of depression could well represent a breakthrough in understanding the etiology of depression. Ketamine was originally used as an anesthetic drug and later its use was extended to other therapeutic applications suc
Externí odkaz: https://doaj.org/article/bd5956fe57ab46d5b4f96f4fdd337dd3
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4
Akademický článek
Experimental Investigations on Dopamine Transmission Can Provide Clues on the Mechanism of the Therapeutic Effect of Amphetamine and Methylphenidate in ADHD
Autor: Ezio Carboni, Alessandra Silvagni
Publikováno v: Neural Plasticity, Vol 11, Iss 1-2, Pp 77-95 (2004)
The aim of this review is to compare the experimental evidence obtained from in vitro studies on the effect of amphetamine and methylphenidate on dopamine transmission with the results obtained in animal models of attention deficit hyperactivity diso
Externí odkaz: https://doaj.org/article/6ba989d8487145bc97af716912b3b6d9
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5
Akademický článek
Prepuberal stimulation of 5-HT7-R by LP-211 in a rat model of hyper-activity and attention-deficit: permanent effects on attention, brain amino acids and synaptic markers in the fronto-striatal interface.
Autor: Lucia A Ruocco, Concetta Treno, Ugo A Gironi Carnevale, Claudio Arra, Gianpiero Boatto, Maria Nieddu, Cristina Pagano, Placido Illiano, Fabiana Barbato, Angela Tino, Ezio Carboni, Giovanni Laviola, Enza Lacivita, Marcello Leopoldo, Walter Adriani, Adolfo G Sadile
Publikováno v: PLoS ONE, Vol 9, Iss 4, p e83003 (2014)
The cross-talk at the prefronto-striatal interface involves excitatory amino acids, different receptors, transducers and modulators. We investigated long-term effects of a prepuberal, subchronic 5-HT7-R agonist (LP-211) on adult behaviour, amino acid
Externí odkaz: https://doaj.org/article/59daa6c3beb54a9490f5dfaae9c4fc34
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6
Akademický článek
Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy?
Autor: Anna R. Carta, Augusta Pisanu, Ezio Carboni
Publikováno v: Parkinson's Disease, Vol 2011 (2011)
Thiazolidinediones (TZDs) are peroxisome proliferator-activated receptor (PPAR)-γ agonists commonly used as insulin-sensitizing drugs for the treatment of type 2 diabetes. In the last decade, PPAR-γ agonists have received increasing attention for t
Externí odkaz: https://doaj.org/article/47b1a529b0074eeb8cb09b53d02b2b6c
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8
BDNF Alterations in Brain Areas and the Neurocircuitry Involved in the Antidepressant Effects of Ketamine in Animal Models, Suggest the Existence of a Primary Circuit of Depression
Autor: Anna R. Carta, Ezio Carboni
Publikováno v: Journal of integrative neuroscience. 21(5)
Major depressive disorder is one of the primary causes of disability and disease worldwide. The therapy of depression is prevalently based on monoamine reuptake blockers; consequently, investigations aimed to clarify the aetiology of depression have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eaec0c5562ab2bbb0c33342aa7fa820
https://pubmed.ncbi.nlm.nih.gov/36137960
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9
Immunomodulatory drugs alleviate l ‐dopa‐induced dyskinesia in a rat model of Parkinson's disease
Autor: Sandro Fenu, Saturnino Spiga, Nigel H. Greig, Augusta Pisanu, Ezio Carboni, Giovanna Mulas, Anna R. Carta, David Tweedie, Laura Boi, Michael T. Scerba
Publikováno v: Movement Disorders. 34:1818-1830
BACKGROUND Thalidomide and closely related analogues are used clinically for their immunomodulatory and antiangiogenic properties mediated by the inhibition of the proinflammatory cytokine tumor necrosis factor α. Neuroinflammation and angiogenesis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88616b4ea9cc7ac6571d3192c198bf82
https://doi.org/10.1002/mds.27799
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10
Modeling Parkinson’s Disease Neuropathology and Symptoms by Intranigral Inoculation of Preformed Human α-Synuclein Oligomers
Autor: Ignazia Mocci, Elzbieta Janda, Anna R. Carta, Saturnino Spiga, Alfonso De Simone, Anna Ena, Maria Antonietta Casu, Maria Scherma, Augusta Pisanu, Ezio Carboni, Giovanna Mulas, Maria Francesca Palmas, Giuliana Fusco, Paola Fadda, Laura Boi, Valentina Satta
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 8535, p 8535 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 22
International journal of molecular sciences
21 (2020): 1–25. doi:10.3390/ijms21228535
info:cnr-pdr/source/autori:Boi L.; Pisanu A.; Palmas M.F.; Fusco G.; Carboni E.; Casu M.A.; Satta V.; Scherma M.; Janda E.; Mocci I.; Mulas G.; Ena A.; Spiga S.; Fadda P.; De Simone A.; Carta A.R./titolo:Modeling Parkinson's disease neuropathology and symptoms by intranigral inoculation of preformed human ?-synuclein oligomers/doi:10.3390%2Fijms21228535/rivista:International journal of molecular sciences (Print)/anno:2020/pagina_da:1/pagina_a:25/intervallo_pagine:1–25/volume:21
The accumulation of aggregated &alpha
synuclein (&alpha
Syn) is a hallmark of Parkinson&rsquo
s disease (PD). Current evidence indicates that small soluble &alpha
Syn oligomers (&alpha
SynOs) are the most toxic species among
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba27676096dba207ee0feca4bcf4ed2b
https://www.mdpi.com/1422-0067/21/22/8535
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