Výsledky vyhledávání - "Ezgi Bakirci"

Akademický článek

The importance of plasmin for the healing of the anterior cruciate ligament

Autor: Ezgi Bakirci, Karin Tschan, Rahel D. May, Sufian S. Ahmad, Barbara Kleer, Benjamin Gantenbein

Publikováno v: Bone & Joint Research, Vol 9, Iss 9, Pp 543-553 (2020)

Aims: The anterior cruciate ligament (ACL) is known to have a poor wound healing capacity, whereas other ligaments outside of the knee joint capsule such as the medial collateral ligament (MCL) apparently heal more easily. Plasmin has been identified

Externí odkaz: https://doaj.org/article/31ab5092b7194b9b98493ed0078a9aa6

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Akademický článek

Genipin-Enhanced Fibrin Hydrogel and Novel Silk for Intervertebral Disc Repair in a Loaded Bovine Organ Culture Model

Autor: Daniela A. Frauchiger, Rahel D. May, Ezgi Bakirci, Adel Tekari, Samantha C. W. Chan, Michael Wöltje, Lorin M. Benneker, Benjamin Gantenbein

Publikováno v: Journal of Functional Biomaterials, Vol 9, Iss 3, p 40 (2018)

(1) Background: Intervertebral disc (IVD) repair represents a major challenge. Using functionalised biomaterials such as silk combined with enforced hydrogels might be a promising approach for disc repair. We aimed to test an IVD repair approach by c

Externí odkaz: https://doaj.org/article/6b902dec8e8f499eb4faf87fbfd9ea3b

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Primary Glial Cell and Glioblastoma Morphology in Cocultures Depends on Scaffold Design and Hydrogel Composition

Autor: Mateo S. Andrade Mier, Ezgi Bakirci, Philipp Stahlhut, Robert Blum, Paul D. Dalton, Carmen Villmann

Publikováno v: Advanced Biology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a65340bd78fb876e9a067562b70ea61
https://doi.org/10.1002/adbi.202300029

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Reinforced Hyaluronic Acid-Based Matrices Promote 3D Neuronal Network Formation

Autor: Dieter Janzen, Ezgi Bakirci, Jessica Faber, Mateo Andrade Mier, Julia Hauptstein, Arindam Pal, Leonard Forster, Jonas Hazur, Aldo R. Boccaccini, Rainer Detsch, Jörg Teßmar, Silvia Budday, Torsten Blunk, Paul D. Dalton, Carmen Villmann

Publikováno v: Advanced healthcare materials. 11(21)

3D neuronal cultures attempt to better replicate the in vivo environment to study neurological/neurodegenerative diseases compared to 2D models. A challenge to establish 3D neuron culture models is the low elastic modulus (30-500 Pa) of the native br

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc22d5e9ab484110453884f8a3a7bdf
https://pubmed.ncbi.nlm.nih.gov/35993391

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The importance of plasmin for the healing of the anterior cruciate ligament

Autor: Benjamin Gantenbein, Rahel Deborah May, Karin Tschan, Ezgi Bakirci, Barbara Katharina Kleer, Sufian S. Ahmad

Publikováno v: Bone & Joint Research, Vol 9, Iss 9, Pp 543-553 (2020)
Bone & Joint Research
Bakirci, Ezgi; Tschan, Karin; May, Rahel D.; Ahmad, Sufian S; Kleer, Barbara; Gantenbein, Benjamin (2020). The importance of plasmin for the healing of the anterior cruciate ligament. Bone & joint research, 9(9), pp. 543-553. British Editorial Society of Bone & Joint Surgery 10.1302/2046-3758.99.BJR-2020-0048.R1

Aims The anterior cruciate ligament (ACL) is known to have a poor wound healing capacity, whereas other ligaments outside of the knee joint capsule such as the medial collateral ligament (MCL) apparently heal more easily. Plasmin has been identified

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ffdf93f96269937cb98cf2ea57c6de
https://online.boneandjoint.org.uk/doi/epdf/10.1302/2046-3758.99.BJR-2020-0048.R1

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The Impact of Including Carbonyl Iron Particles on the Melt Electrowriting Process

Autor: Juliane C. Kade, Ezgi Bakirci, Biranche Tandon, Danila Gorgol, Miroslav Mrlik, Robert Luxenhofer, Paul D. Dalton

Publikováno v: Macromolecular Materials and Engineering

Melt electrowriting, a high-resolution additive manufacturing technique, is used in this study to process a magnetic polymer-based blend for the first time. Carbonyl iron (CI) particles homogenously distribute into poly(vinylidene fluoride) (PVDF) me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69ae1a31510ff3956869efe9eb6bee63
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-318482

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Brain and Breast Cancer Cells with PTEN Loss of Function Demonstrate Enhanced Durotaxis and RHOB Dependent Amoeboid Migration Using 3D Printed Scaffolds and Aligned Microfiber Tracts

Autor: Annalena Wieland, Pamela L. Strissel, Hannah Schorle, Ezgi Bakirci, Dieter Janzen, Matthias W. Beckmann, Markus Eckstein, Paul D. Dalton, Reiner Strick

Background: Glioblastoma multiforme (GBM) and triple-negative breast cancer (TNBC) with PTEN mutations often lead to brain dissemination with very poor patient outcomes. GBM uses axons and vessels as migratory cues to disseminate, however it is not k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fbd77f89e1c0ed3e7977b4bd912e5eff
https://doi.org/10.21203/rs.3.rs-826338/v1

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Brain and Breast Cancer Cells with PTEN Loss of Function Reveal Enhanced Durotaxis and RHOB Dependent Amoeboid Migration Utilizing 3D Scaffolds and Aligned Microfiber Tracts

Autor: Pamela L. Strissel, Hannah Schorle, Matthias W. Beckmann, Reiner Strick, Dieter Janzen, Paul D. Dalton, Markus Eckstein, Ezgi Bakirci, Annalena Wieland

Publikováno v: Cancers
Cancers, Vol 13, Iss 5144, p 5144 (2021)
Volume 13
Issue 20

Simple Summary Glioblastoma multiforme (GBM) and metastatic triple-negative breast cancer (TNBC) with PTEN mutations are associated with brain tumor spreading and poor patient outcomes. GBM, and possibly TNBC, migrate on axons and blood vessels to di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8dde841856d7c4c9528ba220304e47
https://pubmed.ncbi.nlm.nih.gov/34680293

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Spinal Cord Neuronal Network Formation in a 3D Printed Reinforced Matrix-A Model System to Study Disease Mechanisms

Autor: Silvia Budday, Natascha Schaefer, Carmen Villmann, Paul D. Dalton, Ezgi Bakirci, Jessica Faber, Natalie Fischhaber

Publikováno v: Advanced healthcare materials. 10(19)

3D cell cultures allow a better mimicry of the biological and mechanical environment of cells in vivo compared to 2D cultures. However, 3D cell cultures have been challenging for ultrasoft tissues such as the brain. The present study uses a microfibe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594f8d124906de9e258d76697b0be68c
https://pubmed.ncbi.nlm.nih.gov/34350717

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Melt Electrowritten In Vitro Radial Device to Study Cell Growth and Migration

Autor: Ezgi Bakirci, Andrei Hrynevich, Ouafa Dahri, Paul D. Dalton, Reiner Strick, Carmen Villmann, Pamela L. Strissel, Natascha Schaefer

Publikováno v: Advanced biosystems. 4(10)

The development of in vitro assays for 3D microenvironments is essential for understanding cell migration processes. A 3D-printed in vitro competitive radial device is developed to identify preferred Matrigel concentration for glioblastoma migration.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a0c8e709a6027f43434f1d35d8ebb27
https://pubmed.ncbi.nlm.nih.gov/32875734

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