Zobrazeno 1 - 10 of 32 pro vyhledávání: '"Ezgi, Karaesmen"'
1
Akademický článek
Molecular profiling of a real-world breast cancer cohort with genetically inferred ancestries reveals actionable tumor biology differences between European ancestry and African ancestry patient populations
Autor: Minoru Miyashita, Joshua S. K. Bell, Stephane Wenric, Ezgi Karaesmen, Brooke Rhead, Matthew Kase, Kristiyana Kaneva, Francisco M. De La Vega, Yonglan Zheng, Toshio F. Yoshimatsu, Galina Khramtsova, Fang Liu, Fangyuan Zhao, Frederick M. Howard, Rita Nanda, Nike Beaubier, Kevin P. White, Dezheng Huo, Olufunmilayo I. Olopade
Publikováno v: Breast Cancer Research, Vol 25, Iss 1, Pp 1-13 (2023)
Abstract Background Endocrine-resistant HR+/HER2- breast cancer (BC) and triple-negative BC (TNBC) are of interest for molecularly informed treatment due to their aggressive natures and limited treatment profiles. Patients of African Ancestry (AA) ex
Externí odkaz: https://doaj.org/article/006ca307fd264a2eaf4c46f5adf6c1f6
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3
Akademický článek
High dimensional model representation of log likelihood ratio: binary classification with SNP data
Autor: Ali Foroughi pour, Maciej Pietrzak, Lara E. Sucheston-Campbell, Ezgi Karaesmen, Lori A. Dalton, Grzegorz A. Rempała
Publikováno v: BMC Medical Genomics, Vol 13, Iss S9, Pp 1-22 (2020)
Abstract Background Developing binary classification rules based on SNP observations has been a major challenge for many modern bioinformatics applications, e.g., predicting risk of future disease events in complex conditions such as cancer. Small-sa
Externí odkaz: https://doaj.org/article/d6da352384784b5f8411ddfc07adac08
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4
Akademický článek
Genome-Wide Association Analyses Identify Variants in IRF4 Associated With Acute Myeloid Leukemia and Myelodysplastic Syndrome Susceptibility
Autor: Junke Wang, Alyssa I. Clay-Gilmour, Ezgi Karaesmen, Abbas Rizvi, Qianqian Zhu, Li Yan, Leah Preus, Song Liu, Yiwen Wang, Elizabeth Griffiths, Daniel O. Stram, Loreall Pooler, Xin Sheng, Christopher Haiman, David Van Den Berg, Amy Webb, Guy Brock, Stephen Spellman, Marcelo Pasquini, Philip McCarthy, James Allan, Friedrich Stölzel, Kenan Onel, Theresa Hahn, Lara E. Sucheston-Campbell
Publikováno v: Frontiers in Genetics, Vol 12 (2021)
The role of common genetic variation in susceptibility to acute myeloid leukemia (AML), and myelodysplastic syndrome (MDS), a group of rare clonal hematologic disorders characterized by dysplastic hematopoiesis and high mortality, remains unclear. We
Externí odkaz: https://doaj.org/article/fa262d77b31b4da591c8a81a451b985b
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5
Akademický článek
Multiple functional variants in the IL1RL1 region are pretransplant markers for risk of GVHD and infection deaths
Autor: Ezgi Karaesmen, Theresa Hahn, Alexander James Dile, Abbas A. Rizvi, Junke Wang, Tao Wang, Michael D. Haagenson, Leah Preus, Qianqian Zhu, Qian Liu, Li Yan, Song Liu, Christopher A. Haiman, Daniel Stram, Loreall Pooler, Xin Sheng, David Van Den Berg, Guy Brock, Amy Webb, Philip L. McCarthy, Marcelo C. Pasquini, Stephen R. Spellman, Stephanie J. Lee, Sophie Paczesny, Lara E. Sucheston-Campbell
Publikováno v: Blood Advances, Vol 3, Iss 16, Pp 2512-2524 (2019)
Abstract: Graft-versus-host disease (GVHD) and infections are the 2 main causes of death without relapse after allogeneic hematopoietic cell transplantation (HCT). Elevated soluble serum simulation-2 (sST2), the product of IL1RL1 in plasma/serum post
Externí odkaz: https://doaj.org/article/b5a5fbd3681545f893974314a2ebe8d0
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8
Multiomics in primary and metastatic breast tumors from the AURORA US network finds microenvironment and epigenetic drivers of metastasis
Autor: Susana, Garcia-Recio, Toshinori, Hinoue, Gregory L, Wheeler, Benjamin J, Kelly, Ana C, Garrido-Castro, Tomas, Pascual, Aguirre A, De Cubas, Youli, Xia, Brooke M, Felsheim, Marni B, McClure, Andrei, Rajkovic, Ezgi, Karaesmen, Markia A, Smith, Cheng, Fan, Paula I Gonzalez, Ericsson, Melinda E, Sanders, Chad J, Creighton, Jay, Bowen, Kristen, Leraas, Robyn T, Burns, Sara, Coppens, Amy, Wheless, Salma, Rezk, Amy L, Garrett, Joel S, Parker, Kelly K, Foy, Hui, Shen, Ben H, Park, Ian, Krop, Carey, Anders, Julie, Gastier-Foster, Mothaffar F, Rimawi, Rita, Nanda, Nancy U, Lin, Claudine, Isaacs, P Kelly, Marcom, Anna Maria, Storniolo, Fergus J, Couch, Uma, Chandran, Michael, Davis, Jonathan, Silverstein, Alexander, Ropelewski, Minetta C, Liu, Susan G, Hilsenbeck, Larry, Norton, Andrea L, Richardson, W Fraser, Symmans, Antonio C, Wolff, Nancy E, Davidson, Lisa A, Carey, Adrian V, Lee, Justin M, Balko, Katherine A, Hoadley, Peter W, Laird, Elaine R, Mardis, Tari A, King
Publikováno v: Nature cancer.
The AURORA US Metastasis Project was established with the goal to identify molecular features associated with metastasis. We assayed 55 females with metastatic breast cancer (51 primary cancers and 102 metastases) by RNA sequencing, tumor/germline DN
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::93f1fb740e8c81c0546ac85b735dd468
https://pubmed.ncbi.nlm.nih.gov/36585450
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