Výsledky vyhledávání - "Ezequiela Adrover"

Curating the gnomAD database: Report of novel variants in the thyrogobulin gene using in silico bioinformatics algorithms

Autor: Maricel F. Molina, Sofia Siffo, Ezequiela Adrover, Héctor M. Targovnik, Miguel Martin Abelleyro, Karen G. Scheps, Mauricio Gomes Pio, Carina M. Rivolta

Publikováno v: Molecular and cellular endocrinology. 534

Thyroglobulin (TG) is a large glycosylated protein of 2767 amino acids, secreted by the thyrocytes into the follicular lumen. It plays an essential role in the process of thyroid hormone synthesis. TG gene variants lead to permanent congenital hypoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34fdac2a53fa708c79cc8ee745dd9af7
https://pubmed.ncbi.nlm.nih.gov/34119605

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Molecular analysis of thyroglobulin mutations found in patients with goiter and hypothyroidism

Autor: Ana Chiesa, Rogelio González-Sarmiento, Héctor M. Targovnik, Patricia Papendieck, Sofia Siffo, Mirta Miras, Viviana Balbi, Elena Bueno Martinez, Verónica González, Cintia E. Citterio, Gabriela Sobrero, Jacques Weill, Ezequiela Adrover, Carina M. Rivolta

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)

Thyroid dyshormonogenesis due to thyroglobulin (TG) gene mutations have an estimated incidence of approximately 1 in 100,000 newborns. The clinical spectrum ranges from euthyroid to mild or severe hypothyroidism. Up to now, one hundred seventeen dele

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24f3758bd41cd7f7fe05e36e4e8ccd32
http://hdl.handle.net/10261/245013

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Prenatal restraint stress decreases the expression of alpha-7 nicotinic receptor in the brain of adult rat offspring

Autor: Francisco J. Barrantes, Marta C. Antonelli, Carlos Javier Baier, Melisa Carolina Monteleone, Ezequiela Adrover, Marcela Adriana Brocco, Maria Eugenia Pallares

Publikováno v: Stress. 18:435-445

Prenatal stress (PS) strongly impacts fetal brain development and function in adulthood. In normal aging and Alzheimer's disease, there is hypothalamic–pituitary–adrenal axis dysfunction and loss of cholinergic neurons and neuronal nicotinic acet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55bd5c4d1a17fa50550d105b842e6bae
https://doi.org/10.3109/10253890.2015.1022148

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Intrastriatal 6-OHDA Lesion Differentially Affects Dopaminergic Neurons in the Ventral Tegmental Area of Prenatally Stressed Rats

Autor: Carlos Javier Baier, Rita Raisman-Vozari, Ezequiela Adrover, Marta C. Antonelli, Maria R. Katunar, Maria Eugenia Pallares

Publikováno v: Neurotoxicity Research. 26:274-284

Exposure to a variety of stressful events during the last week of pregnancy in rats interferes with the correct progeny development, which in turn leads to delays in motor development, impaired adaptation to stressful conditions, altered sexual behav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08900dfce95a2336c2c4ae228891d1b6
https://doi.org/10.1007/s12640-014-9479-7

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Age-Dependent Effects of Prenatal Stress on the Corticolimbic Dopaminergic System Development in the Rat Male Offspring

Autor: Marta C. Antonelli, Ezequiela Adrover, Carlos Javier Baier, Melisa Carolina Monteleone, Marcela Adriana Brocco, Maria Eugenia Pallares

Publikováno v: Neurochemical Research. 38:2323-2335

We have previously demonstrated that prenatal stress (PS) exerts an impairment of midbrain dopaminergic (DA) system metabolism especially after puberty, suggesting a particular sensitivity of DA development to variations in gonadal hormonal peaks. Fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7545e3378843586ed281b941c8cb03
https://doi.org/10.1007/s11064-013-1143-8

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Glutamate neurotransmission is affected in prenatally stressed offspring

Autor: Marcela Adriana Brocco, Marta C. Antonelli, Carlos Javier Baier, Ezequiela Adrover, Ursula Sonnewald, Fernando Alfredo Giuliani, Helle S. Waagepetersen, Arne Schousboe, Maria Eugenia Pallares, Ricardo Cabrera, Melisa Carolina Monteleone

Publikováno v: Neurochemistry international. 88

Previous studies from our laboratory have shown that male adult offspring of stressed mothers exhibited higher levels of ionotropic and metabotropic glutamate receptors than control rats. These offspring also showed long-lasting astroglial hypertroph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364e0bc9f4a9e72b569f9a45b8a73569
https://pubmed.ncbi.nlm.nih.gov/26026592

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Maternal administration of flutamide during late gestation affects the brain and reproductive organs development in the rat male offspring

Autor: Ezequiela Adrover, Viviana Mesch, Carlos Javier Baier, Mercedes Imsen, Gonzalez D, Bibiana Fabre, Marta C. Antonelli, Maria Eugenia Pallares

Publikováno v: Neuroscience. 278

We have previously demonstrated that male rats exposed to stress during the last week of gestation present age-specific impairments of brain development. Since the organization of the fetal developing brain is subject to androgen exposure and prenata

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc85aab973a9d18c1893f062430d1c30
https://pubmed.ncbi.nlm.nih.gov/25130562

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Prenatal stress changes the glycoprotein GPM6A gene expression and induces epigenetic changes in rat offspring brain

Autor: Marcela Adriana Brocco, Alberto C.C. Frasch, Marta C. Antonelli, Ezequiela Adrover, Maria Eugenia Pallares, Melisa Carolina Monteleone

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Prenatal stress (PS) exerts strong impact on fetal brain development and on adult offspring brain functions. Previous work demonstrated that chronic stress alters the mRNA expression of GPM6A, a neuronal glycoprotein involved in filopodium extension.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e2a2577d38369b4f884aa98eecfe75
http://www.tandfonline.com/doi/full/10.4161/epi.25925

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Prenatal maternal restraint stress exposure alters the reproductive hormone profile and testis development of the rat male offspring

Autor: Carlos Javier Baier, Nadia Bourguignon, Silvia I. González-Calvar, Maria Eugenia Pallares, Marta C. Antonelli, Ezequiela Adrover, Marcela Adriana Brocco, Melisa Carolina Monteleone

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Several studies have demonstrated that the presence of stressors during pregnancy induces adverse effects on the neuroendocrine system of the offspring later in life. In the present work, we investigated the effects of early programming on the male r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ef1a8dbb5c9a224600fdd11efb8cb26
https://pubmed.ncbi.nlm.nih.gov/23252714

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