Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Ezequiel, Calvo"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract The antisense non-coding RNA in the INK locus (ANRIL) is a hotspot for genetic variants associated with cardiometabolic disease. We recently found increased ANRIL abundance in human pancreatic islets from donors with certain Type II Diabetes
Externí odkaz:
https://doaj.org/article/aee20e476ca048aab9bce02bb6a5a17d
Autor:
Maíra Bianchi Rodrigues Alves, Laura Girardet, Céline Augière, Kyeong Hye Moon, Camille Lavoie-Ouellet, Agathe Bernet, Denis Soulet, Ezequiel Calvo, Maria E Teves, Charles Joly Beauparlant, Arnaud Droit, Alexandre Bastien, Claude Robert, Jinwoong Bok, Barry T Hinton, Clémence Belleannée
Publikováno v:
Biology of Reproduction. 108:241-257
Primary cilia play pivotal roles in embryonic patterning and organogenesis through transduction of the Hedgehog signaling pathway (Hh). Although mutations in Hh morphogens impair the development of the gonads and trigger male infertility, the contrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf039b102d824b927c0a808ab461d6dc
https://doi.org/10.1093/biolre/ioac210
https://doi.org/10.1093/biolre/ioac210
Autor:
Feng Wang, Ezequiel Calvo-Roitberg, Julia M Rembetsy-Brown, Minggang Fang, Jacquelyn Sousa, Zachary J Kartje, Pranathi Meda Krishnamurthy, Jonathan Lee, Michael R Green, Athma A Pai, Jonathan K Watts
Publikováno v:
Nucleic Acids Research. 50:12657-12673
Friedreich’s ataxia is an incurable disease caused by frataxin (FXN) protein deficiency, which is mostly induced by GAA repeat expansion in intron 1 of the FXN gene. Here, we identified antisense oligonucleotides (ASOs), complementary to two region
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07683975947b5da54616590d8c4f1481
https://doi.org/10.1093/nar/gkac1108
https://doi.org/10.1093/nar/gkac1108
Autor:
Rémy Nicolle, Yuna Blum, Laetitia Marisa, Celine Loncle, Odile Gayet, Vincent Moutardier, Olivier Turrini, Marc Giovannini, Benjamin Bian, Martin Bigonnet, Marion Rubis, Nabila Elarouci, Lucile Armenoult, Mira Ayadi, Pauline Duconseil, Mohamed Gasmi, Mehdi Ouaissi, Aurélie Maignan, Gwen Lomberk, Jean-Marie Boher, Jacques Ewald, Erwan Bories, Jonathan Garnier, Anthony Goncalves, Flora Poizat, Jean-Luc Raoul, Veronique Secq, Stephane Garcia, Philippe Grandval, Marine Barraud-Blanc, Emmanuelle Norguet, Marine Gilabert, Jean-Robert Delpero, Julie Roques, Ezequiel Calvo, Fabienne Guillaumond, Sophie Vasseur, Raul Urrutia, Aurélien de Reyniès, Nelson Dusetti, Juan Iovanna
Publikováno v:
Cell Reports, Vol 21, Iss 9, Pp 2458-2470 (2017)
Preclinical models based on patient-derived xenografts have remarkable specificity in distinguishing transformed human tumor cells from non-transformed murine stromal cells computationally. We obtained 29 pancreatic ductal adenocarcinoma (PDAC) xenog
Externí odkaz:
https://doaj.org/article/1cd281d48e1a47c3af7a5a5caffb63ca
Autor:
Olivia Jerczynski, Nicolas Lacroix-Pépin, Eric Boilard, Ezequiel Calvo, Agathe Bernet, Michel A Fortier, Ida Björkgren, Petra Sipilä, Clémence Belleannée
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163876 (2016)
Dicer1 is an endoribonuclease involved in the biogenesis of functional molecules such as microRNAs (miRNAs) and endogenous small interfering RNAs (endo-siRNAs). These small non-coding RNAs are important regulators of post-transcriptional gene express
Externí odkaz:
https://doaj.org/article/157103d06bab4727acb7f051c18a2d34
Autor:
Agathe Bernet, Ezequiel Calvo, Charles Joly-Beauparlant, Denis Soulet, Clémence Belleannée, Daniel G. Cyr, Arnaud Droit, Laura Girardet
Publikováno v:
The FASEB Journal. 34:7593-7609
Primary cilia (PC) are organelles that sense and respond to dynamic changes of the extracellular milieu through the regulation of target genes. By using the epididymis as a model system, we determined the contribution of primary cilia in the regulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd24987734e8c9212ad97b3eb3ae8129
https://doi.org/10.1096/fj.202000328r
https://doi.org/10.1096/fj.202000328r
Autor:
GyeungYun Kim, Ezequiel Calvo-Roitberg, Michael P. McGurk, Christopher B. Burge, Athma A. Pai, Ana Fiszbein
Publikováno v:
Science Advances
Messenger RNA isoform differences are predominantly driven by alternative first, internal, and last exons. Despite the importance of classifying exons to understand isoform structure, few tools examine isoform-specific exon usage. We recently observe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c772aa439dd4cc8a8e9be212bea1e473
http://europepmc.org/articles/PMC8769537
http://europepmc.org/articles/PMC8769537
Publikováno v:
BioTechniques, Vol 38, Iss 2, Pp 287-293 (2005)
Quantification of mRNA expression levels using real-time reverse transcription PCR (RT-PCR) is increasingly used to validate results of DNA microarrays or GeneChips®. It requires an improved method that is more robust and more suitable for high-thro
Externí odkaz:
https://doaj.org/article/d24ac87e2d5a449697ee41559413cd9e
Autor:
Juan L. Iovanna, Ezequiel Calvo, Nicolas A. Fraunhoffer, Daniel Closa, Emma Folch-Puy, Analía Meilerman Abuelafia, Eduardo Chuluyan
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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The crosstalk between the transformed tumoral cells and their microenvironment is a key aspect for pancreatic ductal adenocarcinoma (PDAC) progression. This molecular dialog is intensively studied because it may result in an efficient therapeutic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0c121c305f01dee512c3caeb481c596
https://pubmed.ncbi.nlm.nih.gov/34450197
https://pubmed.ncbi.nlm.nih.gov/34450197
Autor:
Ezequiel Calvo, Patrick Blondin, Robert Sullivan, Sylvie Bourassa, Patrick Vincent, Olivier D'Amours
Publikováno v:
Molecular Reproduction and Development. 86:999-1012
In the context of artificial insemination, male fertility is defined as the ability to produce functional spermatozoa able to withstand cryopreservation. We hypothesized that interindividual variations in fertility depend on the proportion of the ful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e442e86a7a32ed7daf346a64c8be4294
https://doi.org/10.1002/mrd.23174
https://doi.org/10.1002/mrd.23174