Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Ezekiell Mouzon"'
Autor:
Efrain A. Ribeiro, Marine Salery, Joseph R. Scarpa, Erin S. Calipari, Peter J. Hamilton, Stacy M. Ku, Hope Kronman, Immanuel Purushothaman, Barbara Juarez, Mitra Heshmati, Marie Doyle, Casey Lardner, Dominicka Burek, Ana Strat, Stephen Pirpinias, Ezekiell Mouzon, Ming-Hu Han, Rachael L. Neve, Rosemary C. Bagot, Andrew Kasarskis, Ja Wook Koo, Eric J. Nestler
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
While making up a small percentage of neurons in the nucleus accumbens, somatostatin interneurons may have important function in dopamine- and addiction-related behavior. Here, Ribeiro and colleagues show that somatostatin interneurons regulate behav
Externí odkaz:
https://doaj.org/article/de460a0a87ff48c7a645aa7091dbb3fb
Autor:
Mitra Heshmati, Rosemary C. Bagot, Marine Salery, Immanuel Purushothaman, Casey Lardner, Dominicka Burek, Erin S. Calipari, Ezekiell Mouzon, Hope Kronman, Andrew Kasarskis, Peter J. Hamilton, Eric J. Nestler, Joseph R. Scarpa, Marie A Doyle, Barbara Juarez, Ana N. Strat, Ja Wook Koo, Efrain Ribeiro, Rachael L. Neve, Ming-Hu Han, Stephen T. Pirpinias, Stacy M. Ku
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature Communications
The role of somatostatin interneurons in nucleus accumbens (NAc), a key brain reward region, remains poorly understood due to the fact that these cells account for
While making up a small percentage of neurons in the nucleus accumbens, somatosta
While making up a small percentage of neurons in the nucleus accumbens, somatosta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4c8cb395680bf1409a7c2b5697ab86
https://doaj.org/article/de460a0a87ff48c7a645aa7091dbb3fb
https://doaj.org/article/de460a0a87ff48c7a645aa7091dbb3fb
Autor:
Di Liu, Jun-Xia Yang, Venetia Zachariou, Ja Wook Koo, Hai-Lei Ding, Mei-Jun Liu, Eric J. Nestler, Yi-Ling Qian, Ming-Hu Han, Lei Wang, Xiao-Yun Guo, Song Zhang, Karl Deisseroth, He Liu, Hongxing Zhang, Jun-Li Cao, Ezekiell Mouzon, Xiao-Yi Wang, Chen Li
Publikováno v:
Biological Psychiatry. 82:608-618
Background The mesolimbic reward system plays a critical role in modulating nociception; however, its underlying molecular, cellular, and neural circuitry mechanisms remain unknown. Methods Chronic constrictive injury (CCI) of the sciatic nerve was u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c0a1939487d53108b55b4f58d6d0657
https://doi.org/10.1016/j.biopsych.2017.02.1180
https://doi.org/10.1016/j.biopsych.2017.02.1180
Autor:
Li Shen, Ning-Yi Shao, HaoSheng Sun, Gustavo Turecki, Mohamed Kabbaj, Jacqui Rabkin, Caroline Dias, Diane M. Damez-Werno, Kimberly N. Scobie, Rachael L. Neve, Ezekiell Mouzon, Katherine N. Wright, Eric J. Nestler
Publikováno v:
Neuroscience. 353:1-6
Chromatin regulation, in particular ATP-dependent chromatin remodelers, have previously been shown to be important in the regulation of reward-related behaviors in animal models of mental illnesses. Here we demonstrate that BAZ1A, an accessory subuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4484a5657ad6f92fa53a8722e1beeb3f
https://doi.org/10.1016/j.neuroscience.2017.04.007
https://doi.org/10.1016/j.neuroscience.2017.04.007
Autor:
Diane M. Damez-Werno, Caroline Dias, Rachael L. Neve, Ning-Yi Shao, Gustavo Turecki, Jaclyn Rabkin, Mary Kay Lobo, Yasmin L. Hurd, C. David Allis, Ernesto Guccione, Ian Maze, Michael E. Cahill, David M. Dietz, Hannah M. Cates, Amy M. Gancarz, Ezekiell Mouzon, Joseph A. Landry, HaoSheng Sun, Ramesh Chandra, Catherine Jensen Pena, Kimberly N. Scobie, Eric J. Nestler, Paola Defilippi, Deena M. Walker, Erin S. Calipari, Li Shen
Publikováno v:
Proceedings of the National Academy of Sciences. 113:9623-9628
Repeated cocaine exposure regulates transcriptional regulation within the nucleus accumbens (NAc), and epigenetic mechanisms-such as histone acetylation and methylation on Lys residues-have been linked to these lasting actions of cocaine. In contrast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d34001b710dcd19ea9e7565401a0f85
https://doi.org/10.1073/pnas.1605045113
https://doi.org/10.1073/pnas.1605045113
Autor:
Sam A. Golden, Erica Korb, Jacqui Rabkin, Rosemary C. Bagot, Elizabeth A. Heller, Hannah M. Cates, Carol A. Tamminga, Ning-Yi Shao, Ja Wook Koo, Gustavo Turecki, Li Shen, Diane M. Damez-Werno, Scott J. Russo, Benoit Labonté, Patrick Varga-Weisz, HaoSheng Sun, Caroline Dias, Kelly Gleason, Eric J. Nestler, Pamela J. Kennedy, Kimberly N. Scobie, Ezekiell Mouzon, Ian Maze, David M. Dietz, Francisca H. Ahn, Simon Andrews, C. David Allis, Michael E. Cahill, Rachael L. Neve
Publikováno v:
Nature medicine
Improved treatment for major depressive disorder (MDD) remains elusive because of the limited understanding of its underlying biological mechanisms. It is likely that stress-induced maladaptive transcriptional regulation in limbic neural circuits con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6880d235f88906040c23bda043e040af
https://doi.org/10.1038/nm.3939
https://doi.org/10.1038/nm.3939
Autor:
Jorge A. Gutiérrez, Stacey L. Thomas, Laila M. Poisson, Ezekiell Mouzon, Sandra A. Rempel, Reima El Naili, Archanna Radakrishnan, Nancy Lemke, Sandra Cottingham, Chad R. Schultz, William A. Golembieski
Publikováno v:
Brain Pathology (Zurich, Switzerland)
BACKGROUND: Both enhanced SPARC expression and the loss of p53 tumor suppressor gene are changes that occur early in glioma development. Both SPARC and p53 regulate glioma cell survival by inverse effects on apoptotic signaling. Therefore, during gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e46f120132b28dff5234828a5b7617
https://doi.org/10.1111/bpa.12161
https://doi.org/10.1111/bpa.12161
Autor:
Marie A. Doyle, Ezekiell Mouzon, Eileen Harrigan, Immanuel Purushothaman, Catherine Jensen Pena, Meelad M. Dawlaty, Amber Brown, Li Shen, Vincent Vialou, Eric J. Nestler, Deena M. Walker, Rudolf Jaenisch, Jian Feng, Olivia Engmann, Orna Issler
Publikováno v:
Neuropsychopharmacology
Neuropsychopharmacology, 2017, 42 (8), pp.1657-1669. ⟨10.1038/npp.2017.6⟩
Neuropsychopharmacology, 2017, 42 (8), pp.1657-1669. ⟨10.1038/npp.2017.6⟩
International audience; Depression is a leading cause of disease burden, yet current therapies fully treat o50% of affected individuals. Increasing evidence implicates epigenetic mechanisms in depression and antidepressant action. Here we examined a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c93b9231bf120941e6ac552f6d3ff15
https://www.hal.inserm.fr/inserm-03949688/document
https://www.hal.inserm.fr/inserm-03949688/document
Autor:
Rosemary C. Bagot, Erin S. Calipari, Michelle S. Mazei-Robison, Ezekiell Mouzon, Li Shen, Efrain Ribeiro, Carol A. Tamminga, Catherine Jensen Pena, HaoSheng Sun, Benoit Labonté, Rachael L. Neve, Xiaochuan Liu, Subroto Ghose, Jian Feng, Caroline Dias, Kimberly N. Scobie, Ning Y.i. Shao, Eric J. Nestler, Pamela J. Kennedy, Vincent Vialou, Ja W.ook Koo, Deveroux Ferguson, Diane M. Damez-Werno
Publikováno v:
Nature. 516:51-55
β-catenin is a multi-functional protein that has an important role in the mature central nervous system; its dysfunction has been implicated in several neuropsychiatric disorders, including depression. Here we show that in mice β-catenin mediates p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c705239b6a7e1016e3b6b233ca7fb4f0
https://doi.org/10.1038/nature13976
https://doi.org/10.1038/nature13976
Autor:
Fiona B. Carr, Karl Deisseroth, Sumana Chakravarty, Rosemary C. Bagot, Venetia Zachariou, Ja Wook Koo, Eugenia Stergiou, Maria Efstratia Tsimpanouli, Sevasti Gaspari, Deveroux Ferguson, Mary Kay Lobo, Ezekiell Mouzon, Maria M. Papachatzaki
Publikováno v:
Neuropsychopharmacology. 39:1968-1977
Regulator of G protein signalling 9-2 (Rgs9-2) modulates the actions of a wide range of CNS-acting drugs by controlling signal transduction of several GPCRs in the striatum. RGS9-2 acts via a complex mechanism that involves interactions with Gα subu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b65cebe2f913055a9e5c10045333c57
https://doi.org/10.1038/npp.2014.45
https://doi.org/10.1038/npp.2014.45