Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Ezekiel, Adebiyi"'
Autor:
Temitope A. Ogunnupebi, Gbolahan O. Oduselu, Oluwadunni F. Elebiju, Olayinka O. Ajani, Ezekiel Adebiyi
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
IntroductionIn malaria management, insecticides play a crucial role in targeting disease vectors. Benzothiazole derivatives have also been reported to possess insecticidal properties, among several other properties they exhibit. The female Anopheles
Externí odkaz:
https://doaj.org/article/72bb8f4c7d8a4933bb01eb710c47d0ea
Publikováno v:
Scientific African, Vol 24, Iss , Pp e02160- (2024)
The high morbidity and mortality from malaria infection, especially amongst children under five years of age, necessitates the production of new antimalarial drugs. Plasmodium falciparum RNA pseudouridylate synthase putative (PfRPuSP) is an essential
Externí odkaz:
https://doaj.org/article/206c60ae0c754e60af2804e9a5520850
Autor:
Gbenga Adegbite, Sunday Edeki, Itunuoluwa Isewon, Jerry Emmanuel, Titilope Dokunmu, Solomon Rotimi, Jelili Oyelade, Ezekiel Adebiyi
Publikováno v:
Infectious Disease Modelling, Vol 8, Iss 4, Pp 1015-1031 (2023)
Malaria importation is one of the hypothetical drivers of malaria transmission dynamics across the globe. Several studies on malaria importation focused on the effect of the use of conventional malaria control strategies as approved by the World Heal
Externí odkaz:
https://doaj.org/article/b0044289aae840a6b73d3907152f6c71
Publikováno v:
Bioinformatics and Biology Insights, Vol 18 (2024)
6-Pyruvoyl tetrahydropterin synthase (6-PTPS) is a lyase involved in the synthesis of tetrahydrobiopterin. In Plasmodium species where dihydroneopterin aldolase (DHNA) is absent, it acts in the folate biosynthetic pathway necessary for the growth and
Externí odkaz:
https://doaj.org/article/a68774c783844dbea51accfc2de91f2d
Autor:
Glory P. Adebayo, Gbolahan O. Oduselu, Damilola V. Aderohunmu, Karel D. Klika, Grace I. Olasehinde, Olayinka O. Ajani, Ezekiel Adebiyi
Publikováno v:
Arabian Journal of Chemistry, Vol 17, Iss 2, Pp 105573- (2024)
Malaria remains a significant global health concern causing numerous fatalities and the emergence of antimalarial drug resistance highlights the urgent need for novel therapeutic options with innovative mechanisms of action and targets. This study ai
Externí odkaz:
https://doaj.org/article/2d07865dbaa349c183cc53f755c129f6
Autor:
Helyaneh Ziaei Jam, Yang Li, Ross DeVito, Nima Mousavi, Nichole Ma, Ibra Lujumba, Yagoub Adam, Mikhail Maksimov, Bonnie Huang, Egor Dolzhenko, Yunjiang Qiu, Fredrick Elishama Kakembo, Habi Joseph, Blessing Onyido, Jumoke Adeyemi, Mehrdad Bakhtiari, Jonghun Park, Sara Javadzadeh, Daudi Jjingo, Ezekiel Adebiyi, Vineet Bafna, Melissa Gymrek
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Tandem repeats (TRs) represent one of the largest sources of genetic variation in humans and are implicated in a range of phenotypes. Here we present a deep characterization of TR variation based on high coverage whole genome sequencing from
Externí odkaz:
https://doaj.org/article/fc3ce6b9d4d04929afdde67a60974243
Autor:
Eunice O Adedeji, Thomas Beder, Claudia Damiani, Alessia Cappelli, Anastasia Accoti, Sofia Tapanelli, Olubanke O Ogunlana, Segun Fatumo, Guido Favia, Rainer Koenig, Ezekiel Adebiyi
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0305207 (2024)
Increasing reports of insecticide resistance continue to hamper the gains of vector control strategies in curbing malaria transmission. This makes identifying new insecticide targets or alternative vector control strategies necessary. CLassifier of E
Externí odkaz:
https://doaj.org/article/dc19d1869641424faacd2db7e04c0150
Autor:
Oluwadunni F. Elebiju, Gbolahan O. Oduselu, Temitope A. Ogunnupebi, Olayinka O. Ajani, Ezekiel Adebiyi
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 543 (2024)
The inhibition of O-acetyl sulphydrylase synthase isoforms has been reported to represent a promising approach for the development of antibiotic adjuvants. This occurs via the organism developing an unpaired oxidative stress response, causing a reduc
Externí odkaz:
https://doaj.org/article/3f9a8ec26fab45e98c9e675bd9f36cf5
Autor:
Gbolahan O. Oduselu, Damilola V. Aderohunmu, Olayinka O. Ajani, Oluwadunni F. Elebiju, Temitope A. Ogunnupebi, Ezekiel Adebiyi
Publikováno v:
Frontiers in Chemistry, Vol 11 (2023)
Introduction: Quinazolin-4(3H)-one derivatives have attracted considerable attention in the pharmacological profiling of therapeutic drug targets. The present article reveals the development of arylidene-based quinazolin-4(3H)-one motifs as potential
Externí odkaz:
https://doaj.org/article/34e2f4d44c6b42c0839e6eb2cf33ed88
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Personalized medicine has been identified as a powerful tool for addressing the myriad of health issues facing different health systems globally. Although recent studies have expanded our understanding of how different factors such as genetics and th
Externí odkaz:
https://doaj.org/article/7053d9cd835e4c509cf08016d02e3f48