Underutilized legumes, Cajanus cajan and Glycine max may bring about antisickling effect in sickle cell disease by modulation of redox homeostasis in sickled erythrocytes and alteration of its functional chemistry.

Autor: Elemo GN; Nutraceutical Laboratories, Nutrition and Toxicology Division, Federal Institute of Industrial Research, Lagos, Nigeria.; Department of Chemical Sciences, Ajayi Crowther University, Oyo, Nigeria., Erukainure OL; Department of Pharmacology, University of the Free State, Bloemfontein, South Africa., Okafor JNC; Nutraceutical Laboratories, Nutrition and Toxicology Division, Federal Institute of Industrial Research, Lagos, Nigeria., Banerjee P; Structural Bioinformatics Group, Institute for Physiology, Charité-University Medicine Berlin, Berlin, Germany., Preissner R; Structural Bioinformatics Group, Institute for Physiology, Charité-University Medicine Berlin, Berlin, Germany., Nwachukwu Nicholas-Okpara VA; Nutraceutical Laboratories, Nutrition and Toxicology Division, Federal Institute of Industrial Research, Lagos, Nigeria., Atolani O; Department of Chemistry, University of Ilorin, Ilorin, Nigeria., Omowunmi O; Laboratory Management & Services, Federal Institute of Industrial Research, Lagos, Nigeria., Ezeanyanaso CS; Polymer & Textile Division, Federal Institute of Industrial Research, Lagos, Nigeria., Awosika A; Temitayo Awosika Help Foundation, Lagos, Nigeria., Shode F; Department of Biotechnology and Food Science, Durban University of Technology, Durban, South Africa.; Sholab Nutraceuticals (Pty) Ltd, Westville North, South Africa.

Publikováno v: Journal of food biochemistry [J Food Biochem] 2022 Sep; Vol. 46 (9), pp. e14322. Date of Electronic Publication: 2022 Jul 27.