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Predicting the Stability of Lyophilized Human Serum Albumin Formulations Containing Sucrose and Trehalose Using Solid-State NMR Spectroscopy: Effect of Storage Temperature on ¹ H T 1 Relaxation Times.

Autor: Lay-Fortenbery A; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, 40536, USA., Tower CW; Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, West Lafayette, IN, 47907, USA., Ezeajughi E; Analytical and Biological Sciences, Medicines & Healthcare Products Regulatory Agency, South Mimms, Hertfordshire, EN6 3QG, UK., Calahan J; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, 40536, USA., Duru C; Analytical and Biological Sciences, Medicines & Healthcare Products Regulatory Agency, South Mimms, Hertfordshire, EN6 3QG, UK., Matejtschuk P; Analytical and Biological Sciences, Medicines & Healthcare Products Regulatory Agency, South Mimms, Hertfordshire, EN6 3QG, UK. paul.matejtschuk@mhra.gov.uk., Munson EJ; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky, 40536, USA. munsone@purdue.edu.; Department of Industrial and Molecular Pharmaceutics, College of Pharmacy, Purdue University, West Lafayette, IN, 47907, USA. munsone@purdue.edu.

Publikováno v: The AAPS journal [AAPS J] 2024 Apr 03; Vol. 26 (3), pp. 40. Date of Electronic Publication: 2024 Apr 03.