Pyridine Carboxamides Based on Sulfobetaines: Design, Reactivity, and Biological Activity.

Autor: Kramarova EP; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Borisevich SS; Laboratory of Physical Chemistry, Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450071 Ufa, Russia., Khamitov EM; Laboratory of Physical Chemistry, Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 450071 Ufa, Russia., Korlyukov AA; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Dorovatovskii PV; National Research Center 'Kurchatov Institute', 123098 Moscow, Russia., Shagina AD; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Mineev KS; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Tarasenko DV; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Novikov RA; N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 119991 Moscow, Russia., Lagunin AA; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Boldyrev I; Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia., Ezdoglian AA; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Karpechenko NY; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Shmigol TA; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Baukov YI; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia., Negrebetsky VV; Department of Medical Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2022 Nov 03; Vol. 27 (21). Date of Electronic Publication: 2022 Nov 03.

A Novel Phenylpyrrolidine Derivative: Synthesis and Effect on Cognitive Functions in Rats with Experimental Ishemic Stroke.

Autor: Borozdenko DA; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Ezdoglian AA; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Shmigol TA; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Gonchar DI; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Lyakhmun DN; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Tarasenko DV; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Golubev YV; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Cherkashova EA; Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Medicine Federal State Budgetary Institution, Federal Center of Brain Research and Neurotechnologies, Federal Medical Bio-logical Agency, 117997 Moscow, Russia., Namestnikova DD; Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Medicine Federal State Budgetary Institution, Federal Center of Brain Research and Neurotechnologies, Federal Medical Bio-logical Agency, 117997 Moscow, Russia., Gubskiy IL; Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Medicine Federal State Budgetary Institution, Federal Center of Brain Research and Neurotechnologies, Federal Medical Bio-logical Agency, 117997 Moscow, Russia., Lagunin AA; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.; Institute of Biomedical Chemistry, 119121 Moscow, Russia., Gubsky LV; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.; Department of Neurology, Neurosurgery and Medical Genetics, Faculty of Medicine Federal State Budgetary Institution, Federal Center of Brain Research and Neurotechnologies, Federal Medical Bio-logical Agency, 117997 Moscow, Russia., Chekhonin VP; Department of Medical Nanobiotechnologies, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Borisevich SS; Laboratory of Physical Chemistry, Ufa Institute of Chemistry UFRS RAS, pr. Oktyabrya 71, 450054 Ufa, Russia., Gureev MA; Laboratory of Bioinformatics, Research Center 'Digital Biodesign and Personalized Healthcare', I.M. Sechenov University, 119991 Moscow, Russia.; Laboratory of Bioinformatics and Computational Modelling of Biological Systems, Department of Computational Biology, Sirius University of Science and Technology, 354340 Sochi, Russia., Shagina AD; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Kiseleva NM; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Negrebetsky VV; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia., Baukov YI; Department of Medicinal Chemistry and Toxicology, Pirogov Russian National Research Medical University, 117997 Moscow, Russia.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Oct 11; Vol. 26 (20). Date of Electronic Publication: 2021 Oct 11.