Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Eyram Adjogatse"'
Autor:
Josh Bennett, Jonathan B. Cooper, Steve P. Wood, Eyram Adjogatse, Peter T. Erskine, Jingxu Guo, Brendan W. Wren
Publikováno v:
Acta Crystallogr F Struct Biol Commun
In many prokaryotes, the first step of threonine metabolism is catalysed by the enzyme threonine dehydrogenase (TDH), which uses NAD+ to oxidize its substrate to 2-amino-3-ketobutyrate. The absence of a functional TDH gene in humans suggests that inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c1e79538289072d9a3090eb7ae4e78b
https://pubmed.ncbi.nlm.nih.gov/34341193
https://pubmed.ncbi.nlm.nih.gov/34341193
Autor:
David L. Selwood, Eyram Adjogatse, Alun R. Coker, Jonathan B. Cooper, Stephen A. Wells, Jonathan D. Wilden, John M. Kelly, Steve Wood, A. W. Edith Chan, P. T. Erskine
Publikováno v:
Adjogatse, E, Erskine, P, Wells, S A, Kelly, J M, Wilden, J D, Chan, A W E, Selwood, D, Coker, A, Wood, S & Cooper, J B 2018, ' Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations ', Acta Crystallographica Section D: Structural Biology, vol. 74, no. 9, pp. 861-876 . https://doi.org/10.1107/S2059798318009208
Acta Crystallographica Section D Structural Biology
Acta Crystallographica Section D Structural Biology
Two of the world's most neglected tropical diseases, human African trypanosomiasis (HAT) and Chagas disease, are caused by protozoan parasites of the genusTrypanosoma. These organisms possess specialized metabolic pathways, frequently distinct from t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592d072143cab75b779a9472d7f2003b