Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Eylon Yavin"'
Autor:
Odelia Tepper-Shimshon, Nino Tetro, Roa’a Hamed, Natalia Erenburg, Emmanuelle Merquiol, Gourab Dey, Agam Haim, Tali Dee, Noa Duvdevani, Talin Kevorkian, Galia Blum, Eylon Yavin, Sara Eyal
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1211 (2024)
The space environment can affect the function of all physiological systems, including the properties of cell membranes. Our goal in this study was to explore the effect of simulated microgravity (SMG) on the cellular uptake of small molecules based o
Externí odkaz:
https://doaj.org/article/a437c92619c2452886187536e3081d90
Publikováno v:
Molecules, Vol 29, Iss 17, p 4136 (2024)
Forced intercalation peptide nucleic acids (FIT-PNAs) are DNA mimics that act as RNA sensors. The sensing event occurs due to sequence-specific RNA hybridization, leading to a substantial increase in fluorescence. The fluorophore in the FIT-PNA is te
Externí odkaz:
https://doaj.org/article/16d2a54cb29343ae9c6d6b4d07fcbb49
Autor:
Sheethal Thomas Mannully, Rawan Mahajna, Huda Nazzal, Salam Maree, Hongchao Zheng, Daniel H. Appella, Reuven Reich, Eylon Yavin
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 609 (2024)
Ovarian cancer (OC) is one of the most lethal gynecologic cancers that is typically diagnosed at the very late stage of disease progression. Thus, there is an unmet need to develop diagnostic probes for early detection of OC. One approach may rely on
Externí odkaz:
https://doaj.org/article/b3b133fc6e13443a9a6fda6c8197c099
Publikováno v:
ACS Omega, Vol 4, Iss 9, Pp 13954-13961 (2019)
Externí odkaz:
https://doaj.org/article/c7e0a6250b724ffebc62d7516dc315da
Autor:
Polina Denichenko, Maxim Mogilevsky, Antoine Cléry, Thomas Welte, Jakob Biran, Odelia Shimshon, Georgina D. Barnabas, Miri Danan-Gotthold, Saran Kumar, Eylon Yavin, Erez Y. Levanon, Frédéric H. Allain, Tamar Geiger, Gil Levkowitz, Rotem Karni
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Alternative splicing, critical for gene expression, is deregulated in many diseases. Here the authors develop decoy oligonucleotides to specifically downregulate splicing factors activity.
Externí odkaz:
https://doaj.org/article/56b48a0782e64173831607d2f384bb24
Autor:
Itamar Peled, Eylon Yavin
Publikováno v:
ACS Omega, Vol 3, Iss 4, Pp 3813-3818 (2018)
Externí odkaz:
https://doaj.org/article/a5eaefef5f084ec2bf409a775cccbf43
Autor:
Eylon Yavin
Publikováno v:
Molecules, Vol 25, Iss 15, p 3317 (2020)
The DNA mimic, PNA (peptide nucleic acid), has been with us now for almost 3 decades [...]
Externí odkaz:
https://doaj.org/article/da3f822770734f9a8de6731e63cf3ff2
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86802 (2014)
One of the major concerns in treating malaria by conventional small drug molecules is the rapid emergence of drug resistance. Specific silencing of essential genes by antisense oliogomers has been proposed as an alternative approach that may result i
Externí odkaz:
https://doaj.org/article/e0320086582b48ed8dc15b8e8050bc73
Autor:
Ezequiel Wexselblatt, Yaara Oppenheimer-Shaanan, Ilana Kaspy, Nir London, Ora Schueler-Furman, Eylon Yavin, Gad Glaser, Joshua Katzhendler, Sigal Ben-Yehuda
Publikováno v:
PLoS Pathogens, Vol 8, Iss 9, p e1002925 (2012)
Finding bacterial cellular targets for developing novel antibiotics has become a major challenge in fighting resistant pathogenic bacteria. We present a novel compound, Relacin, designed to inhibit (p)ppGpp production by the ubiquitous bacterial enzy
Externí odkaz:
https://doaj.org/article/d1f6e73e68eb43c99e4dd57e26c58e24
Autor:
Gadi Cohen, Shimon Lecht, Hadar Arien-Zakay, Keren Ettinger, Orit Amsalem, Mor Oron-Herman, Eylon Yavin, Diana Prus, Simon Benita, Aviram Nissan, Philip Lazarovici
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48803 (2012)
Novel strategies that target the epidermal growth factor receptor (EGFR) have led to the clinical development of monoclonal antibodies, which treat metastatic colorectal cancer (mCRC) but only subgroups of patients with increased wild type KRAS and E
Externí odkaz:
https://doaj.org/article/11914d3ec36447508208142f252a6312