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Autor:
Alexandra T. Eyerman, Robert Langer, Roberta Poceviciute, Taylor Schoettle, Armon Sharei, Derek Y. Jang, Nahyun Cho, Shirley Mao, George C. Hartoularos, Klavs F. Jensen, Emily L. Jackson, Siddharth Jhunjhunwala
Publikováno v:
RSC
Intracellular delivery of materials is a challenge in research and therapeutic applications. Physical methods of plasma membrane disruption have recently emerged as an approach to facilitate the delivery of a variety of macromolecules to a range of c
Autor:
Roberta Poceviciute, Siddhartha Sharma, Omar F. Khan, Tanya Talkar, Judy Lieberman, Shirley Mao, Marylyn M. Addo, Alexandra T. Eyerman, Abigail K. R. Lytton-Jean, Daniel G. Anderson, Mathieu Angin, Robert Langer, Siddharth Jhunjhunwala, George C. Hartoularos, Klavs F. Jensen, Armon Sharei, Radiana Trifonova, Sophia Liu, Megan Heimann, Ulrich H. von Andrian
Publikováno v:
Public Library of Science
PLoS ONE, Vol 10, Iss 4, p e0118803 (2015)
PLoS ONE
PLoS ONE, Vol 10, Iss 4, p e0118803 (2015)
PLoS ONE
Intracellular delivery of biomolecules, such as proteins and siRNAs, into primary immune cells, especially resting lymphocytes, is a challenge. Here we describe the design and testing of microfluidic intracellular delivery systems that cause temporar