Výsledky vyhledávání - "Eye Proteins/physiology"

Enhancer of Zeste Homolog 2 (EZH2) Contributes to Rod Photoreceptor Death Process in Several Forms of Retinal Degeneration and Its Activity Can Serve as a Biomarker for Therapy Efficacy

Autor: Yvan Arsenijevic, Maarten van Lohuizen, Dror Sharon, Francis L. Munier, Karine Schouwey, Adeline Berger, Martial Mbefo, Corinne Kostic, William A. Beltran, Hélène Dolfuss, Avigail Beryozkin, Xavier Gérard, Hoai Viet Tran

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 9331, p 9331 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 17
International journal of molecular sciences, vol. 22, no. 17, pp. 9331

Inherited retinal dystrophies (IRD) are due to various gene mutations. Each mutated gene instigates a specific cell homeostasis disruption, leading to a modification in gene expression and retinal degeneration. We previously demonstrated that the pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317f821b51e09e261a5c8bd11ea19b47
https://www.mdpi.com/1422-0067/22/17/9331

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Pax6 Regulates the Proglucagon Processing Enzyme PC2 and Its Chaperone 7B2▿ †

Autor: Jacques Philippe, Liora S. Katz, Yvan Gosmain, Eric Marthinet

Publikováno v: Molecular and Cellular Biology, Vol. 29, No 8 (2009) pp. 2322-2334

Pax6 is important in the development of the pancreas and was previously shown to regulate pancreatic endocrine differentiation, as well as the insulin, glucagon, and somatostatin genes. Prohormone convertase 2 (PC2) is the main processing enzyme in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c5236d1e1c8118fb84053c76a0e1dc
https://europepmc.org/articles/PMC2663301/

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