Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eyas Dayyoub"'
Publikováno v:
International Journal of Pharmaceutics. 546:86-96
Biomaterials for applications in the urinary tract are challenged with both biofilm formation and encrustation, two highly interconnected processes. While great effort has been achieved developing promising materials there is only a limited choice of
Publikováno v:
International Journal of Pharmaceutics. 531:205-214
Bacterial biofilm and crystalline deposits are the common causes of failure of long-term indwelling urinary catheter. Bacteria colonise the catheter surface causing serious infections in the urinary tract and encrustations that can block the catheter
Autor:
Lili Duse, Udo Bakowsky, Shashank Reddy Pinnapireddy, Nikola Plenagl, Jarmila Jedelská, Eyas Dayyoub, Benjamin Sebastian Seitz, Hendrik Vögeling, Jana Brüßler
Publikováno v:
Materials Science and Engineering: C. 103:109749
Catheter related infections are causing one third of all blood stream infections. The mortality of those infections is very high and the gold standard for catheter related blood stream infections (CR-BSI) is still the removal of the catheter and syst
Publikováno v:
Materials Science and Engineering: C. 33:3018-3024
Here we present a new method for providing nanostructured drug-loaded polymer films which enable control of film surface morphology and delivery of therapeutic agents. Silicon wafers were employed as models for implanted biomaterials and poly(lactic-
Autor:
Udo Bakowsky, Marcus Kehrel, Eyas Dayyoub, Michael Keusgen, Nina Dassinger, Doru Vornicescu, Stefan Merkl
Publikováno v:
physica status solidi (a). 209:832-838
Immobilization of biomolecules on solid surfaces is often combined with a partial loss of functionality. Therefore, smooth immobilization procedures are urgently required. Most recently, a Concanavalin A–Streptavidin (Con A–SAv) fusion protein wa
Publikováno v:
physica status solidi c. 8:1985-1989
For the development of site specific liposomes, high stability and long circulation properties are very promising for the improvement of drug targeting and drug delivery system as well as improvement of bioavailability of efficient bioactive drugs. T
Publikováno v:
physica status solidi (a). 208:1279-1283
Bacteria adhesion on implant surfaces is the major reason for local and systemic infections after implantation. In order to establish an anti-adhesion material, we constructed self-assembly nanostructured surfaces by wetting of poly(lactic-co-glycoli
Autor:
Regina Reul, Tobias Gessler, Eyas Dayyoub, Juliane Nguyen, Udo Bakowsky, Thomas Kissel, Werner Seeger, Thomas Betz, Thomas Schmehl
Publikováno v:
Journal of Controlled Release. 140:47-54
The objective of this study was to develop highly efficient ternary nanocomposites for aerosol gene therapy consisting of a biodegradable polymer core, poly[vinyl-3-(diethylamino)propylcarbamate-co-vinyl acetate-co-vinyl alcohol]-graft-poly(d,l-lacti
Autor:
Eyas Dayyoub, Arnold Grünweller, Ulrike Weirauch, Achim Aigner, Kerstin Lange-Grünweller, Maren Thomas, Udo Bakowsky, Roland K. Hartmann
Publikováno v:
RNA biology. 9(8)
Antisense inhibition of oncogenic or other disease-related miRNAs and miRNA families in vivo may provide novel therapeutic strategies. However, this approach relies on the development of potent miRNA inhibitors and their efficient delivery into cells
Autor:
Thomas Kissel, Eyas Dayyoub, Damla Sahin, Gerhard Klebe, Christian Pfeiffer, A. Biela, Olga Samsonova, Serghei Glinca
Publikováno v:
Acta biomaterialia. 9(2)
The mechanism causing variability in DNA transfection efficacy for low-molecular-weight pDMAEMA (poly(2-(dimethylamino)ethyl methacrylate) and pDMAEMA-b-pHEMA (poly(2-(dimethyl amino)ethylmethacrylate)- block -poly(2-hydroxyl methacrylate)) has so fa