Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Eyal Zcharia"'
Autor:
Sandrine Benhamron, Inna Reiner, Eyal Zcharia, Mizhir Atallah, Amir Grau, Israel Vlodavsky, Dror Mevorach
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35602 (2012)
To reach the lymphatics, migrating dendritic cells (DCs) need to interact with the extracellular matrix (ECM). Heparanase, a mammalian endo-β-D-glucuronidase, specifically degrades heparan sulfate proteoglycans ubiquitously associated with the cell
Externí odkaz:
https://doaj.org/article/61a77801a53449069df762458baea03c
Autor:
David Planer, Shulamit Metzger, Eyal Zcharia, Isaiah D Wexler, Israel Vlodavsky, Tova Chajek-Shaul
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18370 (2011)
BACKGROUND: Heparanase modulates the level of heparan sulfate proteoglycans (HSPGs) which have an important role in multiple cellular processes. Recent studies indicate that HSPGs have an important function in hepatic lipoprotein handling and process
Externí odkaz:
https://doaj.org/article/93eda9337bfe412fbb8338e69865df66
Heparanase promotes engraftment and prevents graft versus host disease in stem cell transplantation.
Autor:
Menachem Bitan, Lola Weiss, Michael Zeira, Eyal Zcharia, Shimon Slavin, Arnon Nagler, Israel Vlodavsky
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10135 (2010)
Heparanase, endoglycosidase that cleaves heparan sulfate side chains of heparan sulfate proteoglycans, plays important roles in cancer metastasis, angiogenesis and inflammation.Applying a mouse model of bone marrow transplantation and transgenic mice
Externí odkaz:
https://doaj.org/article/a662c68f2b634fd0ba958fe9b567ab48
Autor:
Eyal Zcharia, Juan Jia, Xiao Zhang, Lea Baraz, Ulf Lindahl, Tamar Peretz, Israel Vlodavsky, Jin-Ping Li
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5181 (2009)
Heparanase, a mammalian endo-beta-D-glucuronidase, specifically degrades heparan sulfate proteoglycans ubiquitously associated with the cell surface and extracellular matrix. This single gene encoded enzyme is over-expressed in most human cancers, pr
Externí odkaz:
https://doaj.org/article/61b65eac9cb74a1585ff9a54a012e9ef
Autor:
Michael Elkin, Tamar Peretz, Claudio Pisano, Eyal Zcharia, Immanuel Lerner, Esther Hermano, Amichay Meirovitz
Supplementary Figures 1-2 from Role of Heparanase in Radiation-Enhanced Invasiveness of Pancreatic Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::786c0a5af39b4ccce6df96f3a08d75fc
https://doi.org/10.1158/0008-5472.22390409.v1
https://doi.org/10.1158/0008-5472.22390409.v1
Autor:
Adi Nagler, Tamar Peretz, Ruth Atzmon, Arnon Nagler, Avichai Shimoni, Eyal Zcharia, Israel Vlodavsky
Publikováno v:
Anti-Cancer Drugs. 23:1022-1031
Halofuginone, a low-molecular-weight quinazolinone alkaloid that inhibits collagen α1(I), has been shown to suppress cancer growth, metastasis, and angiogenesis. These activities were attributed in part to the inhibition of matrix metalloproteinase-
Autor:
Christopher Spruell, Mordechai Golomb, Laura Indolfi, Elazer R. Edelman, Aaron B. Baker, Israel Vlodavsky, Vijaya B. Kolachalama, Eyal Zcharia, William J. Gibson
Publikováno v:
Journal of the American College of Cardiology. 59:1551-1560
Objectives The purpose of this study was to examine the role of heparanase in controlling thrombosis following vascular injury or endovascular stenting. Background The use of endovascular stents are a common clinical intervention for the treatment of
Autor:
Ariel Rubinstein, Israel Vlodavsky, Immanuel Lerner, Amichay Meirovitz, Ruth Atzmon, Raanan Bulvik, Yoav Sherman, Eyal Zcharia, Michael Elkin, Esther Hermano, Tamar Peretz, Dina Rodkin, Rivka Ishai-Michaeli, Victoria Doviner
Publikováno v:
Journal of Clinical Investigation. 121:1709-1721
Ulcerative colitis (UC) is a chronic inflammatory bowel disease that is closely associated with colon cancer. Expression of the enzyme heparanase is clearly linked to colon carcinoma progression, but its role in UC is unknown. Here we demonstrate for
Autor:
Lola Weiss, Eyal Zcharia, Shimon Slavin, Menachem Bitan, Israel Reibstein, Yakov Fellig, Arnon Nagler, Michael Zeira, Israel Vlodavsky
Publikováno v:
Molecular Immunology. 47:1890-1898
Heparanase is an endo-beta-d-glucuronidase that cleaves heparan sulfate (HS) saccharide chains. The enzyme promotes cell adhesion, migration and invasion and plays a significant role in cancer metastasis, angiogenesis and inflammation. The present st
Autor:
Aaron B. Baker, Israel Vlodavsky, Elazer R. Edelman, Michael Jonas, Adam Groothuis, Eyal Zcharia, Tarek Shazly, Philip Seifert, David S. Ettenson
Publikováno v:
Circulation Research. 104:380-387
Heparan sulfate proteoglycans (HSPGs) are potent regulators of vascular remodeling and repair. Heparanase is the major enzyme capable of degrading heparan sulfate in mammalian cells. Here we examined the role of heparanase in controlling arterial str