Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Eyal Y. Kimchi"'
Autor:
Robert D. Sanders, Leiv Watne, Shawniqua Williams Roberson, Eyal Y. Kimchi, Arjen J.C. Slooter, Colm Cunningham, Kirill V. Nourski, Ben J.A. Palanca, Richard Lennertz, Matthew I. Banks
Publikováno v:
BJA Open, Vol 11, Iss , Pp 100304- (2024)
Summary: In an era of ‘big data’, we propose that a collaborative network approach will drive a better understanding of the mechanisms of delirium, and more rapid development of therapies. We have formed the International Delirium Pathophysiology
Externí odkaz:
https://doaj.org/article/7411cec6a14846b38c0ea7a9a4f99570
Autor:
Christine A. Eckhardt, Haoqi Sun, Preeti Malik, Syed Quadri, Marcos Santana Firme, Daniel K. Jones, Meike vanSleuwen, Aayushee Jain, Ziwei Fan, Jin Jing, Wendong Ge, Husain H. Danish, Caron A. Jacobson, Daniel B. Rubin, Eyal Y. Kimchi, Sydney S. Cash, Matthew J. Frigault, Jong Woo Lee, Jorg Dietrich, M. Brandon Westover
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 10, Pp 1776-1789 (2023)
Abstract Objective To develop an automated, physiologic metric of immune effector cell‐associated neurotoxicity syndrome among patients undergoing chimeric antigen receptor‐T cell therapy. Methods We conducted a retrospective observational cohort
Externí odkaz:
https://doaj.org/article/931eebd756094e1289ead7d2678ffb8b
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113167- (2023)
Summary: The amygdala, cholinergic basal forebrain, and higher-order auditory cortex (HO-AC) regulate brain-wide plasticity underlying auditory threat learning. Here, we perform multi-regional extracellular recordings and optical measurements of acet
Externí odkaz:
https://doaj.org/article/c494319a47f24dd5872133a4378bb077
Autor:
Daniel K. Jones, Christine A. Eckhardt, Haoqi Sun, Ryan A. Tesh, Preeti Malik, Syed Quadri, Marcos Santana Firme, Meike van Sleuwen, Aayushee Jain, Ziwei Fan, Jin Jing, Wendong Ge, Fábio A. Nascimento, Irfan S. Sheikh, Caron Jacobson, Matthew Frigault, Eyal Y. Kimchi, Sydney S. Cash, Jong Woo Lee, Jorg Dietrich, M. Brandon Westover
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract CAR-T cell therapy is an effective cancer therapy for multiple refractory/relapsed hematologic malignancies but is associated with substantial toxicity, including Immune Effector Cell Associated Neurotoxicity Syndrome (ICANS). Improved detec
Externí odkaz:
https://doaj.org/article/0889862c46f24d588d99f5162341e4e0
Autor:
Ryan A. Tesh, BSc, Haoqi Sun, PhD, Jin Jing, PhD, Mike Westmeijer, MSc, Anudeepthi Neelagiri, MD, Subapriya Rajan, MD, Parimala V. Krishnamurthy, MD, Pooja Sikka, BA, Syed A. Quadri, MD, Michael J. Leone, MSc, Luis Paixao, MD, MSc, Ezhil Panneerselvam, MD, Christine Eckhardt, MD, MSc, Aaron F. Struck, MD, Peter W. Kaplan, MD, Oluwaseun Akeju, MD, Daniel Jones, Eyal Y. Kimchi, MD, PhD, M. Brandon Westover, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 1, p e0611 (2022)
OBJECTIVES:. To develop a physiologic grading system for the severity of acute encephalopathy manifesting as delirium or coma, based on EEG, and to investigate its association with clinical outcomes. DESIGN:. This prospective, single-center, observat
Externí odkaz:
https://doaj.org/article/69544c1060714adc917a0897ea317419
Autor:
Blaise Robert, Eyal Y Kimchi, Yurika Watanabe, Tatenda Chakoma, Miao Jing, Yulong Li, Daniel B Polley
Publikováno v:
eLife, Vol 10 (2021)
Basal forebrain cholinergic neurons (BFCNs) project throughout the cortex to regulate arousal, stimulus salience, plasticity, and learning. Although often treated as a monolithic structure, the basal forebrain features distinct connectivity along its
Externí odkaz:
https://doaj.org/article/828633596e094d62b6910a2029fe02b7
Publikováno v:
The Neurohospitalist. 13:188-191
Background: Vision loss accounts for most ophthalmic presentations of giant cell arteritis (GCA), but an important minority of patients present with diplopia and other cranial neuropathies. Case study: Here we present the case of an 84-year-old woman
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26104126973635afc8d24db5fafb0a0f
https://doi.org/10.1177/19418744221139893
https://doi.org/10.1177/19418744221139893
Autor:
Sophia L. Ryan, Xiu Liu, Vanessa McKenna, Manohar Ghanta, Carlos Muniz, Rachel Renwick, M. Brandon Westover, Eyal Y. Kimchi
ObjectivesPatients hospitalized with stroke develop delirium at higher rates than general hospitalized patients. While several medications are associated with existing delirium, it is unknown whether early medication exposures are associated with sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7afd717f2296621168c204030ea2c434
https://doi.org/10.1101/2023.04.27.23288875
https://doi.org/10.1101/2023.04.27.23288875
Autor:
Daniel B. Rubin, Tommy Hosman, Jessica N. Kelemen, Anastasia Kapitonava, Francis R. Willett, Brian F. Coughlin, Eric Halgren, Eyal Y. Kimchi, Ziv M. Williams, John D. Simeral, Leigh R. Hochberg, Sydney S. Cash
Publikováno v:
The Journal of Neuroscience. 42:5007-5020
Consolidation of memory is believed to involve offline replay of neural activity. While amply demonstrated in rodents, evidence for replay in humans, particularly regarding motor memory, is less compelling. To determine whether replay occurs after mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c365c38eaca770682b7c9149790735
https://doi.org/10.1523/jneurosci.2074-21.2022
https://doi.org/10.1523/jneurosci.2074-21.2022
Publikováno v:
bioRxiv
SummaryReappraising neutral stimuli as environmental threats reflects rapid and discriminative changes in sensory processing within the basolateral amygdala (BLA). To understand how BLA inputs are also reorganized during discriminative threat learnin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00c69b24ed964a9b94de40f44e5e11c8
https://europepmc.org/articles/PMC9915656/
https://europepmc.org/articles/PMC9915656/