Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Eyal Amiel"'
Autor:
Bay Vagher, Eyal Amiel
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0299294 (2024)
Dendritic cell (DC) activation is marked by key events including: (I) rapid induction and shifting of metabolism favoring glycolysis for generation of biosynthetic metabolic intermediates and (II) large scale changes in gene expression including the
Externí odkaz:
https://doaj.org/article/677dc38fe5564acca8a9a1a51a781442
Autor:
Diana Cortes-Selva, Lisa Gibbs, J Alan Maschek, Marcia Nascimento, Tyler Van Ry, James E Cox, Eyal Amiel, Keke C Fairfax
Publikováno v:
PLoS Pathogens, Vol 17, Iss 1, p e1009198 (2021)
Macrophages have a defined role in the pathogenesis of metabolic disease and cholesterol metabolism where alternative activation of macrophages is thought to be beneficial to both glucose and cholesterol metabolism during high fat diet induced diseas
Externí odkaz:
https://doaj.org/article/96328531bcf34c72b676ecc76187576b
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
The need for alternative treatments for multiple sclerosis (MS) has triggered copious amounts of research into microbial therapies focused on manipulating the microbiota–gut–brain axis. This comprehensive review was intended to present and system
Externí odkaz:
https://doaj.org/article/52bf3e8c946943ac9547f5af71fcf35d
Autor:
Laura R. Hoyt, Matthew J. Randall, Jennifer L. Ather, Daniel P. DePuccio, Christopher C. Landry, Xi Qian, Yvonne M. Janssen-Heininger, Albert van der Vliet, Anne E. Dixon, Eyal Amiel, Matthew E. Poynter
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 883-896 (2017)
Alcohol use disorders are common both in the United States and globally, and are associated with a variety of co-morbid, inflammation-linked diseases. The pathogenesis of many of these ailments are driven by the activation of the NLRP3 inflammasome,
Externí odkaz:
https://doaj.org/article/31019ce6d6fc49589bc4750f96e96c8b
Autor:
Julia P. Snyder, Eyal Amiel
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Dendritic cell (DC) activation is characterized by an acute increase in glucose metabolic flux that is required to fuel the high anabolic rates associated with DC activation. Inhibition of glycolysis significantly attenuates most aspects of DC immune
Externí odkaz:
https://doaj.org/article/b04c380c3f674f8e8af0d5ed05d86ba4
Autor:
Kylie D. Curtis, Portia R. Smith, Hannah W. Despres, Julia P. Snyder, Tyler C. Hogan, Princess D. Rodriguez, Eyal Amiel
Publikováno v:
Cells, Vol 9, Iss 3, p 715 (2020)
Dendritic cells (DCs) increase their metabolic dependence on glucose and glycolysis to support their maturation, activation-associated cytokine production, and T-cell stimulatory capacity. We have previously shown that this increase in glucose metabo
Externí odkaz:
https://doaj.org/article/b39712c60e1e4339bc72e69ae1dbb374
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002490 (2012)
In schistosomiasis patients, parasite eggs trapped in hepatic sinusoids become foci for CD4+ T cell-orchestrated granulomatous cellular infiltrates. Since the immune response is unable to clear the infection, the liver is subjected to ongoing cycles
Externí odkaz:
https://doaj.org/article/5eb7ad546d48419fbd75af904946d918
Autor:
Stanley Ching-Cheng Huang, Tori C Freitas, Eyal Amiel, Bart Everts, Erika L Pearce, James B Lok, Edward J Pearce
Publikováno v:
PLoS Pathogens, Vol 8, Iss 10, p e1002996 (2012)
Schistosomes, parasitic flatworms that cause the neglected tropical disease schistosomiasis, have been considered to have an entirely carbohydrate based metabolism, with glycolysis playing a dominant role in the adult parasites. However, we have disc
Externí odkaz:
https://doaj.org/article/314fccf4cce94b6fa8de0252852cd36b
Publikováno v:
Am J Physiol Cell Physiol
Cells regulate their cell volume, but cell volumes may change in response to metabolic and other perturbations. Many metabolomics experiments use cultured cells to measure changes in metabolites in response to physiological and other experimental per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6bc09e9cee7af0f897510ff29462cbb
https://doi.org/10.1152/ajpcell.00613.2020
https://doi.org/10.1152/ajpcell.00613.2020
Publikováno v:
Endocrinology
Anaplastic thyroid cancer (ATC) is one of the most lethal solid tumors, yet there are no effective, long-lasting treatments for ATC patients. Most tumors, including tumors of the endocrine system, exhibit an increased consumption of glucose to fuel c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186a6c5613ba3190db3739023b128746
https://europepmc.org/articles/PMC10233255/
https://europepmc.org/articles/PMC10233255/
