Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eyad Naser"'
Autor:
Sara Oubari, Ute Hegenbart, Renate Schoder, Maximilian Steinhardt, Maria Papathanasiou, Tienush Rassaf, Andreas Thimm, Tim Hagenacker, Eyad Naser, Ulrich Duhrsen, Hans C. Reinhardt, Martin Kortum, Hermine Agis, Stefan Schonland, Alexander Carpinteiro
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Treatment of patients with Mayo stage IIIb light chain (AL) amyloidosis is still challenging, and the prognosis remains very poor. Mayo stage IIIb patients were excluded from the pivotal trial leading to the approval of daratumumab in combination wit
Externí odkaz:
https://doaj.org/article/8a76de74b39b4d61bccab7a8030ffca6
Autor:
Matthias Hose, Anne Günther, Eyad Naser, Fabian Schumacher, Tina Schönberger, Julia Falkenstein, Athanasios Papadamakis, Burkhard Kleuser, Katrin Anne Becker, Erich Gulbins, Adriana Haimovitz-Friedman, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Publikováno v:
eLife, Vol 11 (2022)
Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism. Asm hydrolyzes sphingomyelin to ceramide, which is further metabolized to sphingosine by Ac. Ceramide generates ceramide-enriched platforms that are involv
Externí odkaz:
https://doaj.org/article/e8451a73e0d644448fa86305cbe73999
Autor:
Eyad Naser, Stephanie Kadow, Fabian Schumacher, Zainelabdeen H. Mohamed, Christian Kappe, Gabriele Hessler, Barbara Pollmeier, Burkhard Kleuser, Christoph Arenz, Katrin Anne Becker, Erich Gulbins, Alexander Carpinteiro
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 6, Pp 896-910 (2020)
Inhibition of acid sphingomyelinase (ASM), a lysosomal enzyme that catalyzes the hydrolysis of sphingomyelin into ceramide and phosphorylcholine, may serve as an investigational tool or a therapeutic intervention to control many diseases. Specific AS
Externí odkaz:
https://doaj.org/article/5e9c3b6587c9418bb93a4e4217043165
Autor:
Tom Adomati, Lamin B. Cham, Thamer A. Hamdan, Hilal Bhat, Vikas Duhan, Fanghui Li, Murtaza Ali, Elisabeth Lang, Anfei Huang, Eyad Naser, Vishal Khairnar, Sarah-Kim Friedrich, Judith Lang, Justa Friebus-Kardash, Michael Bergerhausen, Maximilian Schiller, Yara Maria Machlah, Florian Lang, Dieter Häussinger, Stanislav Ferencik, Cornelia Hardt, Philipp A. Lang, Karl S. Lang
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3671-3681.e5 (2020)
Summary: Infections can result in a temporarily restricted unresponsiveness of the innate immune response, thereby limiting pathogen control. Mechanisms of such unresponsiveness are well studied in lipopolysaccharide tolerance; however, whether mecha
Externí odkaz:
https://doaj.org/article/adb0a8a0b0c54307b1e06bb9c186cfaa
Autor:
Anne Günther, Matthias Hose, Eyad Naser, Fabian Schumacher, Tina Schönberger, Julia Falkenstein, Athanasios Papadamakis, Burkhard Kleuser, Katrin Anne Becker, Erich Gulbins, Adriana Haimovitz-Friedman, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d5fdc45fe5ad6cf08e75ebc4e8a084b
https://doi.org/10.7554/elife.83073.sa2
https://doi.org/10.7554/elife.83073.sa2
Autor:
Anne Günther, Matthias Hose, Eyad Naser, Fabian Schumacher, Tina Schönberger, Julia Falkenstein, Athanasios Papadamakis, Burkhard Kleuser, Katrin Anne Becker, Erich Gulbins, Adriana Haimovitz-Friedman, Jan Buer, Astrid M Westendorf, Wiebke Hansen
Acid sphingomyelinase (Asm) and acid ceramidase (Ac) are parts of the sphingolipid metabolism. Asm hydrolyzes sphingomyelin to ceramide, which is further metabolized to sphingosine by Ac. Ceramide generates ceramide-enriched platforms that are involv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4000277328b34513ffbd37d8c380f3
https://doi.org/10.7554/elife.83073
https://doi.org/10.7554/elife.83073
Autor:
Tienush Rassaf, Lukas Kessler, Ulrich Dührsen, Christoph Kimmich, Christoph Rischpler, Andreas Thimm, Jan Dürig, Hans Christian Reinhardt, Alexander Carpinteiro, Stefan Schönland, Tim Hagenacker, Karl-Heinz Jöckel, Eyad Naser, Maria Papathanasiou, Ute Hegenbart, Peter Luedike, Sara Oubari
Publikováno v:
European journal of haematologyREFERENCES. 107(4)
OBJECTIVE To study the impact of time to diagnosis on cardiac Mayo stages, treatment outcome, and overall survival. METHODS We retrospectively analyzed 77 consecutive patients diagnosed between 2015 and 2020 with AL amyloidosis and cardiac involvemen
Autor:
Burkhard Kleuser, Eyad Naser, Christian Kappe, Barbara Pollmeier, Fabian Schumacher, Gabriele Hessler, Katrin Anne Becker, Alexander Carpinteiro, Zainelabdeen H. Mohamed, Stephanie Kadow, Erich Gulbins, Christoph Arenz
Publikováno v:
Journal of Lipid Research
Journal of Lipid Research, Vol 61, Iss 6, Pp 896-910 (2020)
Journal of Lipid Research, Vol 61, Iss 6, Pp 896-910 (2020)
Inhibition of acid sphingomyelinase (ASM), a lysosomal enzyme that catalyzes the hydrolysis of sphingomyelin into ceramide and phosphorylcholine, may serve as an investigational tool or a therapeutic intervention to control many diseases. Specific AS
Publikováno v:
Chemistry (Weinheim an Der Bergstrasse, Germany)
Activity of acid sphingomyelinase has been implicated in a number of diseases like acute lung injury, sepsis or metastasis of melanoma cells. Here, we present a sphingomyelinase FRET probe based on FAM/BODIPY dyes for real‐time monitoring of acid s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a35eb1b1e2dd3190959624dc975def
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85083650561
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85083650561
Autor:
Sarah-Kim Friedrich, Michael Bergerhausen, Yara Maria Machlah, Hilal Bhat, Vikas Duhan, Philipp A. Lang, Cornelia Hardt, Stanislav Ferencik, Maximilian Schiller, Thamer A. Hamdan, Judith Lang, Florian Lang, Elisabeth Lang, Karl S. Lang, Fanghui Li, Tom Adomati, Eyad Naser, Anfei Huang, Dieter Häussinger, Lamin B. Cham, Vishal Khairnar, Justa Friebus-Kardash, Murtaza Ali
Publikováno v:
Cell Reports, Vol 30, Iss 11, Pp 3671-3681.e5 (2020)
Summary: Infections can result in a temporarily restricted unresponsiveness of the innate immune response, thereby limiting pathogen control. Mechanisms of such unresponsiveness are well studied in lipopolysaccharide tolerance; however, whether mecha