Zobrazeno 1 - 10
of 483
pro vyhledávání: '"Extrachromosomal circular DNA"'
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Gestational diabetes mellitus (GDM) significantly impacts maternal and infant health both immediately and over the long term, yet effective early diagnostic biomarkers are currently lacking. Thus, it is essential to identify early
Externí odkaz:
https://doaj.org/article/2262bdb256274af980681c63df638296
Publikováno v:
Cellular & Molecular Biology Letters, Vol 29, Iss 1, Pp 1-24 (2024)
Abstract Background Extrachromosomal circular DNA (eccDNA), a kind of circular DNA that originates from chromosomes, carries complete gene information, particularly the oncogenic genes. This study aimed to examine the contributions of FAM84B induced
Externí odkaz:
https://doaj.org/article/16f0993bc3234b6a837e36e27741833b
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Transposable elements (TEs) are a major force in the evolution of plant genomes. Differences in the transposition activities and landscapes of TEs can vary substantially, even in closely related species. Interspecific hybridization, a widely
Externí odkaz:
https://doaj.org/article/5633c6dc41fa4f4f88335b8debb52840
Autor:
Qingliu He, Qingfu Su, Chengcheng Wei, Pu Zhang, Weihui Liu, Junyi Chen, Xiaoping Su, Wei Zhuang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundThe role of focal amplifications and extrachromosomal circular DNA (eccDNA) is still uncertain in prostate adenocarcinoma (PRAD). Here, we first mapped the global characterizations of eccDNA and then investigate the characterization of eccD
Externí odkaz:
https://doaj.org/article/aeaa2c8f04424d60bb34d6e403df5faa
Autor:
Xiao-Qing Yuan, Nan Zhou, Shi-Jian Song, Yi-Xia Xie, Shui-Qin Chen, Teng-Fei Yang, Xian Peng, Chao-Yang Zhang, Ying-Hua Zhu, Li Peng
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36659- (2024)
Extrachromosomal circular DNA (eccDNA), a pervasive yet enigmatic component of the eukaryotic genome, exists autonomously from its chromosomal counterparts. Ubiquitous in eukaryotes, eccDNA plays a critical role in the orchestration of cellular proce
Externí odkaz:
https://doaj.org/article/603f567683774fc88c62df8f417084c1
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Human extrachromosomal circular DNA, or eccDNA, has been the topic of extensive investigation in the last decade due to its prominent regulatory role in the development of disorders including cancer. With the rapid advancement of experimental, sequen
Externí odkaz:
https://doaj.org/article/47328f2366fa4feaaa48387228798114
Autor:
Sen Ren, Du Wu, Xiaoyong Shen, Qian Wu, Chengcheng Li, Hewei Xiong, Zhongwei Xiong, Rui Gong, Zheng Liu, Wei Wang, Jincao Chen
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background The functional impairment of adipose stem cells (ASCs) during aging limits their clinical transformation. Studies have shown that extrachromosomal circular DNAs (eccDNAs) are associated with tumor progression and cell aging, but t
Externí odkaz:
https://doaj.org/article/e6b9da3859ef4c36834e4d2c6a7e6af7
Autor:
Jaeryuk Kim, Seung-Pyo Hong, Seyoon Lee, Woochan Lee, Dakyung Lee, Rokhyun Kim, Young Jun Park, Sungji Moon, Kyunghyuk Park, Bukyoung Cha, Jong-Il Kim
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-15 (2023)
Abstract Background Fragmentomics, the investigation of fragmentation patterns of cell-free DNA (cfDNA), has emerged as a promising strategy for the early detection of multiple cancers in the field of liquid biopsy. However, the clinical application
Externí odkaz:
https://doaj.org/article/8b998c061fa34b3d9c74505a98d53d26
Autor:
Panagiotis Tsiakanikas, Konstantina Athanasopoulou, Ioanna A. Darioti, Vasiliki Taxiarchoula Agiassoti, Stamatis Theocharis, Andreas Scorilas, Panagiotis G. Adamopoulos
Publikováno v:
Life, Vol 14, Iss 8, p 922 (2024)
Extrachromosomal circular DNA (eccDNA) is a form of a circular double-stranded DNA that exists independently of conventional chromosomes. eccDNA exhibits a broad and random distribution across eukaryotic cells and has been associated with tumor-relat
Externí odkaz:
https://doaj.org/article/3026ff82ba6646399103fe802af6fb18
Autor:
Enze Deng, Xiaoying Fan
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 488 (2024)
Extrachromosomal circular DNA (eccDNA), a double-stranded circular DNA molecule found in multiple organisms, has garnered an increasing amount of attention in recent years due to its close association with the initiation, malignant progression, and h
Externí odkaz:
https://doaj.org/article/d94fbc3b2a3c453b8f956dc0badf4a90