Zobrazeno 1 - 10
of 1 938
pro vyhledávání: '"Extracellular trap"'
Autor:
Jiachi Jia, Yuhang Wang, Mengjia Li, Fuqi Wang, Yingnan Peng, Junhong Hu, Zhen Li, Zhilei Bian, Shuaixi Yang
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Metastasis has been one of the primary reasons for the high mortality rates associated with tumours in recent years, rendering the treatment of current malignancies challenging and representing a significant cause of recurrence in patients w
Externí odkaz:
https://doaj.org/article/035b7d3b84c84cc7b54a254ec1e98d45
Autor:
Zezhong Mou, Yiling Chen, Jinzhong Hu, Yun Hu, Lujia Zou, Xinan Chen, Shenghua Liu, Qiuping Yin, Jian Gong, Shuchen Li, Shanhua Mao, Chenyang Xu, Haowen Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 3916-3930 (2024)
Tumor relapse and metastasis are the major causes of mortality associated with urothelial cancer. In the tumor microenvironment, negative regulatory molecules and various immune cell subtypes suppress antitumor immunity. The inflammatory microenviron
Externí odkaz:
https://doaj.org/article/8171b419e6c14c90997b7f0b643393ca
Autor:
Jian Gao, Jun Liu, Jilin Lu, Xiaofei Zhang, Wei Zhang, Qian Li, Jiayi Cai, Mengjun Li, Yu Gan, Yifan Tang, Shuangjie Wu
Publikováno v:
Advanced Science, Vol 11, Iss 41, Pp n/a-n/a (2024)
Abstract The mechanisms underlying the development and progression of colon cancer are not fully understood. Herein, Src kinase associated phosphoprotein 1 (SKAP1), an immune cell adaptor, is identified as a novel colon cancer‐related gene. SKAP1 e
Externí odkaz:
https://doaj.org/article/5edeac5bf7a14a0a900eb3ed3ad9f93f
Autor:
Yeonju Seo, Se Ik Kim, Sang Hoon Song, Jisoo G. Kim, Ja-Yoon Gu, Hye Won Jeon, Maria Lee, Hyun Kyung Kim
Publikováno v:
Translational Oncology, Vol 49, Iss , Pp 102072- (2024)
Objective: Neutrophils produce neutrophil extracellular traps (NETs) by releasing nuclear contents into the extracellular environment. NETs are associated with systemic inflammation and cancer development and progression. We aimed to investigate whet
Externí odkaz:
https://doaj.org/article/8a7b8066d8874bc7948d04f7a75a4d83
Autor:
Khushbu Priya, Hiral Thacker, Manaswi Chaubey, Madhukar Rai, Shambhavi Singh, Sonali Rawat, Kiran Giri, Sujata Mohanty, Geeta Rai
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSystemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. Both
Externí odkaz:
https://doaj.org/article/0f87245863d24c87ab285e6d0c192147
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesThere is already substantial evidence indicating that neutrophil extracellular trap (NET) formation contributes to the inflammatory cascade in ulcerative colitis (UC). However, the precise regulatory mechanisms governing this process remain
Externí odkaz:
https://doaj.org/article/e7cea087734040d4b28f4955070f55ed
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37357- (2024)
Background: Neutrophil extracellular trap (NET) is associated with host response, tumorigenesis, and immune dysfunction. However, the link between NET and the tumor microenvironment (TME) of gastric cancer (GC) remains unclear. Our study aims to char
Externí odkaz:
https://doaj.org/article/0abc6671532048efa4d9ac5ba33fcbed
Publikováno v:
Dermatologica Sinica, Vol 42, Iss 2, Pp 80-88 (2024)
Pemphigoid diseases (PDs) are a group of autoimmune blistering diseases, including bullous pemphigoid, epidermolysis bullosa acquisita, mucous membrane pemphigoid, linear immunoglobulin A disease, and other rare variants. These diseases are character
Externí odkaz:
https://doaj.org/article/537e81c4b0824bef86bd06112bc2cf61
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-19 (2024)
Abstract Stroke is a prevalent global acute cerebrovascular condition, with ischaemic stroke being the most frequently occurring type. After a stroke, neutrophils accumulate in the brain and subsequently generate and release neutrophil extracellular
Externí odkaz:
https://doaj.org/article/f8ebd5224bb24e41b78102a697d4e8ed
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 538-550 (2024)
Neutrophil extracellular traps (NETs) are implicated in gastric cancer (GC) growth, metastatic dissemination, cancer-associated thrombosis, etc. This work is conducted to elucidate the heterogeneity of NETs in GC. The transcriptome heterogeneity of N
Externí odkaz:
https://doaj.org/article/e706bb6f2d154511a81e3341a4e7efa0