miR‐200a/b/‐429 downregulation is a candidate biomarker of tumor radioresistance and independent of hypoxia in locally advanced cervical cancer

Autor: Anja Nilsen, Tiril Hillestad, Vilde E. Skingen, Eva‐Katrine Aarnes, Christina S. Fjeldbo, Tord Hompland, Tina Sandø Evensen, Trond Stokke, Gunnar B. Kristensen, Beata Grallert, Heidi Lyng

Publikováno v: Molecular Oncology, Vol 16, Iss 6, Pp 1402-1419 (2022)

Many patients with locally advanced cervical cancer experience recurrence within the radiation field after chemoradiotherapy. Biomarkers of tumor radioresistance are required to identify patients in need of intensified treatment. Here, the biomarker

Externí odkaz: https://doaj.org/article/93f75c6bb99d41ab923b3b2b4e9c7452

Collagen gel contraction assays: From modelling wound healing to quantifying cellular interactions with three-dimensional extracellular matrices

Autor: Qing Zhang, Pudi Wang, Xu Fang, Feng Lin, Jing Fang, Chunyang Xiong

Publikováno v: European Journal of Cell Biology, Vol 101, Iss 3, Pp 151253- (2022)

Cells respond to and actively remodel the extracellular matrix (ECM). The dynamic and bidirectional interaction between cells and ECM, especially their mechanical interactions, has been found to play an essential role in triggering a series of comple

Externí odkaz: https://doaj.org/article/d4025ee264c64a1ba8472aa440f76b99

Comparative proteomics analysis reveals the difference during antler regeneration stage between red deer and sika deer

Autor: Hang Su, Xiaolei Tang, Xiaocui Zhang, Li Liu, Li Jing, Daian Pan, Weijie Sun, Huinan He, Chonghui Yang, Daqing Zhao, He Zhang, Bin Qi

Publikováno v: PeerJ, Vol 7, p e7299 (2019)

Deer antler, as the only mammalian regenerative appendage, provides an optimal model to study regenerative medicine. Antler harvested from red deer or sika deer were mainly study objects used to disclose the mechanism underlying antler regeneration o

Externí odkaz: https://doaj.org/article/91b21bfaff64460791ef0f0da103ba7a

A computational framework for modeling cell���matrix interactions in soft biological tissues

Autor: Roland C. Aydin, Maximilian J. Grill, Iman Davoodi Kermani, Wolfgang A. Wall, Jay D. Humphrey, Jonas F. Eichinger, Christian J. Cyron

Publikováno v: Biomechanics and Modeling in Mechanobiology
Biomechanics and Modeling in Mechanobiology 20 (5): 1851-1870 (2021-10-01)
Eichinger, J.F.; Grill, M.J.; Kermani, I.D.; Aydin, R.C.; Wall, W.A.; Humphrey, J.D.; Cyron, C.J.: A computational framework for modeling cell–matrix interactions in soft biological tissues. In: Biomechanics and Modeling in Mechanobiology. Vol. 20 (2021) 1851-1870. (DOI: /10.1007/s10237-021-01480-2)

Living soft tissues appear to promote the development and maintenance of a preferred mechanical state within a defined tolerance around a so-called set point. This phenomenon is often referred to as mechanical homeostasis. In contradiction to the pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bfef8371fc88e78bde357607c6b1f3a

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