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Unraveling the AKT/ERK cascade and its role in Parkinson disease.

Autor: Keshri PK; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India., Singh SP; Department of Biochemistry, Institute of Science, Banaras Hindu University, Varanasi, 221005, Uttar Pradesh, India. sps.biochem23@gmail.com.

Publikováno v: Archives of toxicology [Arch Toxicol] 2024 Oct; Vol. 98 (10), pp. 3169-3190. Date of Electronic Publication: 2024 Aug 13.

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Akademický článek

Combined transcriptome and proteome analysis reveals MSN and ARFIP2 as biomarkers for trastuzumab resistance of breast cancer.

Autor: Shi X; Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Key Laboratory of Marine Biotechnology, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China., Sheng Y; Department of Pharmacy, Sir Run Run Hospital, Nanjing Medical University, Nanjing, 211116, China., Fei H; Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Key Laboratory of Marine Biotechnology, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China., Wei B; Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Key Laboratory of Marine Biotechnology, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China., Zhang Z; Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Key Laboratory of Marine Biotechnology, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China., Xia X; Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Key Laboratory of Marine Biotechnology, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China., Mao C; Department of General Surgery, Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & The Affiliated Cancer Hospital of Nanjing Medical University, Nanjing, 210009, China. lfmcfdd@126.com., Si X; Jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening, Jiangsu Key Laboratory of Marine Biotechnology, Co-Innovation Center of Jiangsu Marine Bio-Industry Technology, School of Pharmacy, Jiangsu Ocean University, Lianyungang, 222005, China. sixx@jou.edu.cn.

Publikováno v: Breast cancer research and treatment [Breast Cancer Res Treat] 2024 Aug; Vol. 207 (1), pp. 187-201. Date of Electronic Publication: 2024 May 15.

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Akademický článek

The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells.

Autor: de Zeeuw, Pauline^1,2,3 (AUTHOR), Treps, Lucas^1,2,4 (AUTHOR), García-Caballero, Melissa^1,2,5 (AUTHOR), Harjes, Ulrike^1,2 (AUTHOR), Kalucka, Joanna^1,2,6 (AUTHOR), De Legher, Carla^1,2 (AUTHOR), Brepoels, Katleen^1,2 (AUTHOR), Peeters, Kristel^1,2 (AUTHOR), Vinckier, Stefan^1,2 (AUTHOR), Souffreau, Joris^1,2 (AUTHOR), Bouché, Ann^1,2 (AUTHOR), Taverna, Federico^1,2,7 (AUTHOR), Dehairs, Jonas⁸ (AUTHOR), Talebi, Ali⁸ (AUTHOR), Ghesquière, Bart^9,10 (AUTHOR), Swinnen, Johan⁸ (AUTHOR), Schoonjans, Luc^1,2 (AUTHOR), Eelen, Guy^1,2,11 (AUTHOR) guy.eelen@droialabs.com, Dewerchin, Mieke^1,2 (AUTHOR) mieke.dewerchin@kuleuven.be, Carmeliet, Peter^1,2,12 (AUTHOR) peter.carmeliet@kuleuven.be

Publikováno v: Communications Biology. 5/23/2024, Vol. 7 Issue 1, p1-17. 17p.

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Inhibition of adenylyl cyclase by GTPase-deficient Gαi is mechanistically different from that mediated by receptor-activated Gαi.

Autor: Chung, Yin Kwan^1,2 (AUTHOR), Chan, Ho Yung¹ (AUTHOR), Lee, Tung Yeung¹ (AUTHOR), Wong, Yung Hou^1,3 (AUTHOR) boyung@ust.hk

Publikováno v: Cell Communication & Signaling. 4/5/2024, Vol. 22 Issue 1, p1-25. 25p.

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Cyclosporine-induced kidney damage was halted by sitagliptin and hesperidin via increasing Nrf2 and suppressing TNF-α, NF-κB, and Bax.

Autor: Abd-Eldayem, Ahmed M.^1,2 (AUTHOR) dr.ahmed2016@aun.edu.eg, Makram, Sohayla Mahmoud² (AUTHOR), Messiha, Basim Anwar Shehata³ (AUTHOR), Abd-Elhafeez, Hanan H.⁴ (AUTHOR), Abdel-Reheim, Mustafa Ahmed^3,5 (AUTHOR)

Publikováno v: Scientific Reports. 3/28/2024, Vol. 14 Issue 1, p1-21. 21p.

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Investigation of HCAR2 antagonists as a potential strategy to modulate bovine leukocytes.

Autor: Mamedova, Laman K.^1,2 (AUTHOR), Krogstad, Kirby C.¹ (AUTHOR), McDonald, Paiton O.³ (AUTHOR), Pokhrel, Laxman⁴ (AUTHOR), Hua, Duy H.⁴ (AUTHOR), Titgemeyer, Evan C.² (AUTHOR), Bradford, Barry J.^1,2 (AUTHOR) bjbrad@msu.edu

Publikováno v: Journal of Animal Science & Biotechnology. 3/6/2024, Vol. 15 Issue 1, p1-11. 11p.

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