Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Experimental organisms"'
Autor:
Luca Perico, Marina Morigi, Anna Pezzotta, Daniela Corna, Valerio Brizi, Sara Conti, Cristina Zanchi, Fabio Sangalli, Piera Trionfini, Sara Buttò, Christodoulos Xinaris, Susanna Tomasoni, Carlamaria Zoja, Giuseppe Remuzzi, Ariela Benigni, Barbara Imberti
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports
Scientific Reports
Abnormal kidney development leads to lower nephron number, predisposing to renal diseases in adulthood. In embryonic kidneys, nephron endowment is dictated by the availability of nephron progenitors, whose self-renewal and differentiation require a r
Akademický článek
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Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Aquatic organisms are often exposed briefly to high pesticide concentration. Survival time model was used to study risk of death in C. gariepinus and O. niloticus fingerlings exposed to 24 mg/L atrazine, 42 mg/l mancozeb, 1 mg/L chlorpyrifos and 0.75
Autor:
Yoshie Kametani, Asuka Miyamoto, Yusuke Ohno, Fuyuki Kametani, Shino Ohshima, Toshiro Seki, Banri Tsuda, Hirofumi Kashiwagi, Kiyoshi Ando, Shunsuke Nakada, Ryoji Ito, Atsushi Yasuda, Mamoru Ito, Yukie Kasama, Yutaka Tokuda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Scientific Reports
Scientific Reports
The status of humoral immunity of cancer patients is not clear compared to cellular immunity because the ability of specific antibody production is difficult to analyze in vitro. We previously developed a humanized mouse model to evaluate antigen-spe
Autor:
Joan-Marc Servitja, Marcelina Párrizas, Carlos Castaño, Gema Alcarraz-Vizán, Daniela Díaz-Catalán, Joel Montane, Júlia Rodríguez-Comas, Anna Novials, Juan Moreno-Vedia, Sara de Pablo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Amyloid deposits in pancreatic islets, mainly formed by human islet amyloid polypeptide (hIAPP) aggregation, have been associated with loss of β-cell mass and function, and are a pathological hallmark of type 2 diabetes (T2D). Treatment with chapero
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
Delivering appropriate stimuli remains a challenge in vision research, particularly for aquatic animals such as zebrafish. Due to the shape of the water tank and the associated optical paths of light rays, the stimulus can be subject to unwanted refr
Autor:
Romain-Daniel Gosselin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Non-transparent statistical reporting contributes to the reproducibility crisis in life sciences, despite guidelines and educational articles regularly published. Envisioning more effective measures for ensuring transparency requires the detailed mon
Autor:
Catherine M. Keenan, Matthew N. Hill, Vincent Chiang, Haley A. Vecchiarelli, Quentin J. Pittman, Kira D. Leitl, Kaitlyn Tan, Alessia Santori, Min Qiao, Keith A. Sharkey, Maria Morena
Publikováno v:
Neuropsychopharmacology
Peripheral inflammatory conditions, including those localized to the gastrointestinal tract, are highly comorbid with psychiatric disorders such as anxiety and depression. These behavioral symptoms are poorly managed by conventional treatments for in
A sensitive mNeonGreen reporter system to measure transcriptional dynamics in Drosophila development
Autor:
Stefano, Ceolin, Monika, Hanf, Marta, Bozek, Andrea Ennio, Storti, Nicolas, Gompel, Ulrich, Unnerstall, Christophe, Jung, Ulrike, Gaul
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)
Communications Biology
Communications Biology
The gene regulatory network governing anterior–posterior axis formation in Drosophila is a well-established paradigm to study transcription in developmental biology. The rapid temporal dynamics of gene expression during early stages of development,
Autor:
Estelle De Roeck, Vincianne Jenart, Thuy Hang Nguyen, Anne-Emilie Decleves, Alexandra Belayew, Aline Derenne, Eugénie Ansseau, Alexandre Legrand, Alexandra Tassin, Frédérique Coppée
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific Reports
Intramuscular injection and electroporation of naked plasmid DNA (IMEP) has emerged as a potential alternative to viral vector injection for transgene expression into skeletal muscles. In this study, IMEP was used to express the DUX4 gene into mouse