Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Experiences in Long-Term Care"'
Publikováno v:
Innovation in Aging
Intimacy continues to be important in later life, including for older adults in long-term care settings such as assisted living (AL). Our past work shows that intimacy is a multi-dimensional process and can involve a variety of partners. Drawing on d
Publikováno v:
Innovation in Aging
Cerebrovascular disease (CvD) is the second most common cause of dementia. Its associated pathology, such as white matter lesions (WML), is associated with reduced cognition. Due to the high variability, the relevance of WML location remains unknown.
Autor:
Dorian K. Rose, Jared W. Skinner, Samuel S. Wu, David E. Clark, Adam J. Woods, P. Lysne, Sudeshna A. Chatterjee
Publikováno v:
Innovation in Aging
Walking function is compromised with older age, particularly for cognitively demanding complex walking tasks. Frontal lobe brain networks are important to both complex walking and cognitive function. There is a need for interventions that target this
Publikováno v:
Innovation in Aging
Frailty is increasingly recognised for its association with adverse health outcomes including mortality. However, various measures are used to assess frailty, and the strength of association could vary depending on the specific definition used. This
Publikováno v:
Innovation in Aging
Old age generally leads to smaller, weaker and slower skeletal muscles. To address the independent effects of weakness vs. slowing on fatigue in aging, we used a custom ergometer in a whole-body, 3 tesla magnetic resonance system to quantify knee ext
Autor:
Christopher T. Whitlow, Jeongchul Kim, Suzanne Craft, Carol A. Shively, Brett M. Frye, Thomas C. Register, Samuel N. Lockhart
Publikováno v:
Innovation in Aging
Diet may influence the risk for cognitive decline and neurodegenerative disorders, including Alzheimer’s disease (AD), but these relationships are difficult to study in humans. Cynomolgus macaques (Macaca fascicularis) are appropriate models for in
Autor:
Rosa R. Baier, Jessica Ogarek, Ellen McCreedy, Kali S. Thomas, Roee Gutman, Faye Dvorchak, James L. Rudolph, Vincent Mor
Publikováno v:
Innovation in Aging
Using the National Institutes of Health (NIH) Stage Model framework, we are conducting a Stage III/IV embedded trial to evaluate the effects of personalized music on agitated behaviors in nursing home (NH) residents with dementia under two research c
Publikováno v:
Innovation in Aging
Hypoxia signaling is essential for angiogenesis and metabolic regulation during exercise. Our previous study has demonstrated an age-related loss of ARNT resulting in limited muscle regeneration. To explore the role of hypoxia signaling in physiologi
Autor:
Svetlana V. Ukraintseva, Qihua Tan, Mary F. Feitosa, Konstantin G. Arbeev, Anatoliy I. Yashin, Dequing Wu, Alexander M. Kulminski, Eric Stallard
Publikováno v:
Innovation in Aging
Yashin, A, Wu, D, Arbeev, K, Stallard, E, Tan, Q, Kulminski, A, Feitosa, M & Ukraintseva, S 2020, ' Role of Genetic Interactions in Alzheimer’s Disease: Lessons from Long Life Family Study (LLFS) ', Innovation in Aging, vol. 4, no. Suppl. 1, pp. 491-491 . https://doi.org/10.1093/geroni/igaa057.1589
Yashin, A, Wu, D, Arbeev, K, Stallard, E, Tan, Q, Kulminski, A, Feitosa, M & Ukraintseva, S 2020, ' Role of Genetic Interactions in Alzheimer’s Disease: Lessons from Long Life Family Study (LLFS) ', Innovation in Aging, vol. 4, no. Suppl. 1, pp. 491-491 . https://doi.org/10.1093/geroni/igaa057.1589
Experimental and clinical studies of Alzheimer’s disease (AD) provide plentiful evidence of AD heterogeneity and involvement of many interacting genes and pathways in regulation of AD-related traits. However, detailed mechanisms of genetic interact
Autor:
Theresa Chrisman
Publikováno v:
Innovation in Aging
Depression and lack of meaning in life (MIL) are common among residents of nursing homes (NHs) and contribute to a reduction in overall health and well-being. Life Story Book (LSB), a reminiscence intervention, is designed to provide a person with th