Zobrazeno 1 - 10
of 397
pro vyhledávání: '"Exonuclease 1"'
Publikováno v:
Asian Journal of Andrology, Vol 25, Iss 5, Pp 643-645 (2023)
Male infertility is a major reproductive disorder, which is clinically characterized by highly heterogeneous phenotypes of abnormal sperm count or quality. To date, five male patients with biallelic loss-of-function (LOF) variants of PARN-like ribonu
Externí odkaz:
https://doaj.org/article/36823caca8214b5f8c8a1c2e434993fb
Publikováno v:
Radiation Medicine and Protection, Vol 2, Iss 4, Pp 146-154 (2021)
Exonuclease 1 (EXO1) can catalyze nucleotide chain excision with its conserved N-terminal domain of 5′ to 3′ exonuclease activity, enabling it to influence diverse biological processes facing the challenges of genotoxic environmental factors such
Externí odkaz:
https://doaj.org/article/210fef7beb1440f28b32bace6ef2bf6e
Publikováno v:
BMC Neurology, Vol 21, Iss 1, Pp 1-5 (2021)
Abstract Background Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations (RVCL-S) is an adult-onset rare monogenic microvasculopathy. Its typical neuroimaging features are punctate white matter lesions or pseudotumor alt
Externí odkaz:
https://doaj.org/article/16b7f4c533c44014b35c2614ea27d8b8
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 2, Pp 457-484 (2021)
Northern blotting (NB), a gold standard for RNA detection, has lost its charm due to its hands-on nature, need for good quality RNA, and radioactivity. With the emergence of the field of microRNAs (miRNAs), the necessity for sensitive and quantitativ
Externí odkaz:
https://doaj.org/article/87bc01d4e4e246dcb9e77b973b214008
Akademický článek
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Autor:
Raíssa Bernardes da Silva, Willian dos Reis Bertoldo, Lucila Langoni Naves, Fernanda Bernadelli de Vito, Jeziel Dener Damasceno, Luiz Ricardo Orsini Tosi, Carlos Renato Machado, André Luiz Pedrosa
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2022)
Leishmania parasites are the causative agents of a group of neglected tropical diseases known as leishmaniasis. The molecular mechanisms employed by these parasites to adapt to the adverse conditions found in their hosts are not yet completely unders
Externí odkaz:
https://doaj.org/article/5dc92e692af7435e9e923520da228285
Autor:
Faruk Incecik, Sibel Balci, Rabia Miray Kisla Ekinci, Ozlem M Herguner, Atil Bisgin, Mustafa Yilmaz
Publikováno v:
Annals of Indian Academy of Neurology, Vol 23, Iss 5, Pp 699-703 (2020)
Three prime repair exonuclease 1 (TREX1) degrades single- and double-stranded DNA with 3’-5’ exonuclease activity. TREX1 mutations are related to type 1 interferon-mediated autoinflammation owing to accumulated intracellular nucleic acids. Severa
Externí odkaz:
https://doaj.org/article/4b7cfba5ccfb4792ae03363261cd1f54
Autor:
Birong Shen, Joseph H Chapman, Michael F Custance, Gianna M Tricola, Charles E Jones, Anthony V Furano
Publikováno v:
eLife, Vol 9 (2020)
Abundant APOBEC3 (A3) deaminase-mediated mutations can dominate the mutational landscape (‘mutator phenotype’) of some cancers, however, the basis of this sporadic vulnerability is unknown. We show here that elevated expression of the bifunctiona
Externí odkaz:
https://doaj.org/article/ce441559108f41af984626194a456241
Publikováno v:
Radiation Medicine and Protection, Vol 2, Iss 4, Pp 146-154 (2021)
Exonuclease 1 (EXO1) can catalyze nucleotide chain excision with its conserved N-terminal domain of 5′ to 3′ exonuclease activity, enabling it to influence diverse biological processes facing the challenges of genotoxic environmental factors such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd296cd6338007d0aceb68d319c2ac06
https://doi.org/10.1016/j.radmp.2021.08.004
https://doi.org/10.1016/j.radmp.2021.08.004
Autor:
Shu Dai, Zhenhong Zhu, Qian-wei Xiong, Hongliang Xia, Xiangming Yan, Shi-zhong Cai, Wei Liu, Zhou-rui Ma
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6448-6458 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 1, Pp 6448-6458 (2021)
Human melanoma is a highly aggressive type of cancer, causing significant mortalities despite the advances in treatment. Carboplatin is a cisplatin analog necessary for the treatment of various cancers and can also be used to treat human melanoma. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9fe3de5246fe2c7cd026ccaeeb38553
http://europepmc.org/articles/PMC8806763
http://europepmc.org/articles/PMC8806763