The Antiviral Effect of the Chemical Compounds Targeting DED/EDh Motifs of the Viral Proteins on Lymphocytic Choriomeningitis Virus and SARS-CoV-2

Autor: Mya Myat Ngwe Tun, Kouichi Morita, Takeshi Ishikawa, Shuzo Urata

Publikováno v: Viruses, Vol 13, Iss 7, p 1220 (2021)

Arenaviruses and coronaviruses include several human pathogenic viruses, such as Lassa virus, Lymphocytic choriomeningitis virus (LCMV), SARS-CoV, MERS-CoV, and SARS-CoV-2. Although these viruses belong to different virus families, they possess a com

Externí odkaz: https://doaj.org/article/cc08899f505645938b791d8be85f0d04

Coronavirus RNA Proofreading: Molecular Basis and Therapeutic Targeting

Autor: Fran Robson, Palma Rocchi, Sinem Demirbag, Thi Khanh Le, Khadija Shahed Khan, Clément Paris, Peter Barfuss, Wai-Lung Ng

Publikováno v: Molecular Cell
Molecular Cell, Elsevier, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩
Molecular Cell, 2020, 79 (5), pp.710-727. ⟨10.1016/j.molcel.2020.07.027⟩

Summary The coronavirus disease 2019 (COVID-19) that is wreaking havoc on global public health and economies has heightened awareness about the lack of effective antiviral treatments for human coronaviruses (CoVs). Many current antivirals, notably nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32e7c3d34b3a0e2ab6d0db7eece5c7f1
https://pubmed.ncbi.nlm.nih.gov/33338403

The Antiviral Effect of the Chemical Compounds Targeting DED/EDh Motifs of the Viral Proteins on Lymphocytic Choriomeningitis Virus and SARS-CoV-2.

Autor: Ngwe Tun MM; Department of Virology, Institute of Tropical Medicine and Leading Program, Graduate School of Biomedical Science, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan., Morita K; Department of Virology, Institute of Tropical Medicine and Leading Program, Graduate School of Biomedical Science, Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan., Ishikawa T; Department of Chemistry, Biotechnology and Chemical Engineering, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Korimoto, Kagoshima 890-0065, Japan., Urata S; National Research Center for the Control and Prevention of Infectious Diseases (CCPID), Nagasaki University, 1-12-4 Sakamoto, Nagasaki 852-8523, Japan.

Publikováno v: Viruses [Viruses] 2021 Jun 24; Vol. 13 (7). Date of Electronic Publication: 2021 Jun 24.