Effect of Starvation on the Endocytic Pathway in Dictyostelium Cells

Autor: Pierre Cosson, Ewan W. Smith, Wanessa Cristina Lima, Steve J. Charette

Publikováno v: Eukaryotic Cell, Vol. 9, No 3 (2010) pp. 387-392

Dictyostelium discoideum amoebae have been used extensively to study the structure and dynamics of the endocytic pathway. Here, we show that while the general structure of the endocytic pathway is maintained in starved cells, its dynamics rapidly slo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b349e21ea627ba6114a13b86ad983633
https://doi.org/10.1128/ec.00285-09

Mitochondrial signals in glucose‐stimulated insulin secretion in the beta cell

Autor: Pierre Maechler, Claes B. Wollheim

Publikováno v: The Journal of Physiology, Vol. 529 Pt 1 (2000) pp. 49-56

Glucose-induced insulin secretion is determined by signals generated in the mitochondria. The elevation of ATP is necessary for the membrane-dependent increase in cytosolic Ca2+, the main trigger of insulin exocytosis. Beta cells depleted of mitochon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1adea58a956c415a763cd1173bd3db
https://doi.org/10.1111/j.1469-7793.2000.00049.x

Short-term synaptic plasticity, simulation of nerve terminal dynamics, and the effects of protein kinase C activation in rat hippocampus

Autor: Darrin H. Brager, Scott M. Thompson, Marco Capogna

Publikováno v: Brager, D H, Capogna, M & Thompson, S M 2002, ' Short-term synaptic plasticity, simulation of nerve terminal dynamics, and the effects of protein kinase C activation in rat hippocampus ', The Journal of Physiology, vol. 541, no. Pt 2, pp. 545-59 .
Aarhus University

Phorbol esters are hypothesised to produce a protein kinase C (PKC)-dependent increase in the probability of transmitter release via two mechanisms: facilitation of vesicle fusion or increases in synaptic vesicle number and replenishment. We used a c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a02c6d75323ff5c10b08a691debbe03
http://ora.ox.ac.uk/objects/uuid:fff53048-bda8-4c45-9855-3572a8216e9d

Role of mitochondrial calcium in metabolism-secretion coupling in nutrient-stimulated insulin release

Autor: Kennedy, Eleanor, Wollheim, Claes

Publikováno v: Diabetes & Metabolism, Vol. 24, No 1 (1998) pp. 15-24

Glucose-stimulated insulin release from pancreatic beta cells involves a complex series of signalling pathways. In many forms of diabetes, lesions in this process cause or aggravate the diabetic phenotype. A common motif in these cascades is the elev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1400::3492339ebfddfb53c02ee1d1c7f153cb
https://archive-ouverte.unige.ch/unige:35646

Activity-dependent mobilization of the adhesion molecule polysialic NCAM to the cell surface of neurons and endocrine cells

Autor: Jochen Lang, Genevieve Rougon, Sylviane Olive, Daniela Harry, William F. Pralong, Jozsef Zoltan Kiss, Danielle Baetens, Cheng Wang

Publikováno v: Scopus-Elsevier
EMBO Journal, Vol. 13, No 22 (1994) pp. 5284-5292

The alpha-2,8-linked sialic acid polymer (PSA) on the neural cell adhesion molecule (NCAM) is an important regulator of cell surface interactions. We have examined the translocation of PSA-NCAM to the surface of cultured cortical neurons and insulin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afa19d6789969f3885d30e2198dc773e
https://pubmed.ncbi.nlm.nih.gov/7957094