Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Exing Wang"'
Autor:
Qianjin Guo, Zi-Ming Cheng, Hector Gonzalez-Cantú, Matthew Rotondi, Gabriela Huelgas-Morales, Purushoth Ethiraj, Zhijun Qiu, Jonathan Lefkowitz, Wan Song, Bethany N. Landry, Hector Lopez, Cynthia M. Estrada-Zuniga, Shivi Goyal, Mohammad Aasif Khan, Timothy J. Walker, Exing Wang, Faqian Li, Yanli Ding, Lois M. Mulligan, Ricardo C.T. Aguiar, Patricia L.M. Dahia
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113070- (2023)
Summary: The TMEM127 gene encodes a transmembrane protein of poorly known function that is mutated in pheochromocytomas, neural crest-derived tumors of adrenomedullary cells. Here, we report that, at single-nucleus resolution, TMEM127-mutant tumors s
Externí odkaz:
https://doaj.org/article/74efd737d1554c5e84e35c4daa5fe892
Autor:
Kenneth W. Dunn, Exing Wang
Publikováno v:
BioTechniques, Vol 28, Iss 3, Pp 542-550 (2000)
Refinements in design have simplified confocal microscopy to the extent that it has become a standard research tool in cell biology. However, as confocal microscopes have become more powerful, they have also become more demanding of their optical com
Externí odkaz:
https://doaj.org/article/eeb54bccd39d415f98cd30ca9adbc227
Autor:
Bruce A. Molitoris, Yehia Mechref, Yifan Huang, Sudhanshu Kumar, Ruben M. Sandoval, Silvia B. Campos-Bilderback, Exing Wang, Jingfu Zhao, Shiv Pratap Singh Yadav, George J. Rhodes, Mark C. Wagner
Publikováno v:
Am J Physiol Renal Physiol
Chronic kidney disease results in high serum urea concentrations leading to excessive protein carbamylation, primarily albumin. This is associated with increased cardiovascular disease and mortality. Multiple methods were used to address whether carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10c4ecb1fde128181563f76ca0476a2b
https://doi.org/10.1152/ajprenal.00428.2020
https://doi.org/10.1152/ajprenal.00428.2020
Autor:
Yilun Deng, Anne-Paule Gimenez-Roqueplo, Afaf Saliba, Shahida K. Flores, Patricia L. M. Dahia, Nelly Burnichon, Ziming Cheng, Irene Chu, Exing Wang, Xingyu Zhang, Sifan Tao, Ricardo C.T. Aguiar
Publikováno v:
J Clin Endocrinol Metab
Context TMEM127 is a poorly known tumor suppressor gene associated with pheochromocytomas, paragangliomas, and renal carcinomas. Our incomplete understanding of TMEM127 function has limited our ability to predict variant pathogenicity. Purpose To bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c3624b25fb58b5c33d2c8fad1979ff3
https://pubmed.ncbi.nlm.nih.gov/32575117
https://pubmed.ncbi.nlm.nih.gov/32575117
Autor:
Yilun Deng, Ziming Cheng, Patricia L. M. Dahia, Ricardo C.T. Aguiar, Shahida K. Flores, Exing Wang, Afaf Saliba, Xingyu Zhang, Irene Chu, Sifan Tao
PurposeTo better understand the function of the transmembrane protein TMEM127, a poorly known tumor suppressor gene associated with pheochromocytomas, paragangliomas and renal carcinomas, we evaluated patient-derived germline variants.MethodsSubcellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693cff7e28fe1181395a78caffec75a6
https://doi.org/10.1101/2020.04.08.031039
https://doi.org/10.1101/2020.04.08.031039
Autor:
Exing Wang, Shahida K. Flores, Patricia L. M. Dahia, Subramanya Srikantan, Yuejuan Qin, Yilun Deng, Zi Ming Cheng, Kris S. Vogel, Anqi Luo
Publikováno v:
Human Molecular Genetics. 27:1794-1808
The TMEM127 tumor suppressor gene encodes a transmembrane protein of unknown function mutated in pheochromocytomas and, rarely, in renal cancers. Tumors with inactivating TMEM127 mutations have increased mTORC1 signaling by undefined mechanisms. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ff96c2822a796aea68377e876e1471
https://doi.org/10.1093/hmg/ddy095
https://doi.org/10.1093/hmg/ddy095
Publikováno v:
Langmuir. 34:4673-4680
Artificial lipid membranes incorporating proteins have frequently been used as models for the dynamic organization of biological structures in living cells as well as in the development of biology-inspired technologies. We report here on the experime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a4963b77e094a18b4bdb8dd5a7e1a3e
https://doi.org/10.1021/acs.langmuir.7b03708
https://doi.org/10.1021/acs.langmuir.7b03708
Autor:
Tzu-Hung Hsiao, Exing Wang, Zhenqing Ye, Pei-Yin Hsu, A. L. Profit, Ismail Jatoi, Yi Chen, Zelton D Sharp, Nameer B. Kirma, Victor X. Jin, Hui-ming Huang, Hang-Kai Hsu
Publikováno v:
Oncogene
Recruitment of transcription machinery to target promoters for aberrant gene expression has been well studied, but underlying control directed by distant-acting enhancers remains unclear in cancer development. Our previous study demonstrated that dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5521ec095b2c7b1bc474f28499fe136
https://doi.org/10.1038/onc.2015.298
https://doi.org/10.1038/onc.2015.298
Autor:
Yadav, Shiv Pratap S., Sandova, Ruben M., Jingfu Zhao, Yifan Huang, Exing Wang, Kumar, Sudhanshu, Campos-Bilderback, Silvia B., Rhodes, George, Mechref, Yehia, Molitoris, Bruce A., Wagner, Mark C.
Publikováno v:
American Journal of Physiology: Renal Physiology; Jan2021, Vol. 320 Issue 1, pF144-F129, 16p
Publikováno v:
Apoptosis. 19:816-828
The signaling pathways via mTOR (mammalian target of rapamycin) and AMPK (AMP-activated protein kinase) play key roles in transcription, translation and carcinogenesis, and may be activated by light exposure. These pathways can be modulated by natura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a40dd8fb0f27846ed34dec700b632f53
https://doi.org/10.1007/s10495-013-0962-z
https://doi.org/10.1007/s10495-013-0962-z