SP-101, A Novel Adeno-Associated Virus Gene Therapy for the Treatment of Cystic Fibrosis, Mediates Functional Correction of Primary Human Airway Epithelia From Donors with Cystic Fibrosis.

Autor: Excoffon KJDA; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Lin S; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Narayan PKL; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Sitaraman S; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Jimah AM; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Fallon TT; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., James ML; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Glatfelter MR; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Limberis MP; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Smith MD; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA., Guffanti G; Sumitomo Pharma America, New York, New York, USA., Kolbeck R; Spirovant Sciences, Inc., Philadelphia, Pennsylvania, USA.

Publikováno v: Human gene therapy [Hum Gene Ther] 2024 Sep; Vol. 35 (17-18), pp. 695-709. Date of Electronic Publication: 2024 Aug 29.

The magic of MAGI-1: A scaffolding protein with multi signalosomes and functional plasticity.

Autor: Excoffon KJDA, Avila CL, Alghamri MS, Kolawole AO

Publikováno v: Biology of the cell [Biol Cell] 2023 Nov; Vol. 115 (11), pp. e202300901. Date of Electronic Publication: 2023 Oct 09.

The Coxsackievirus and Adenovirus Receptor Has a Short Half-Life in Epithelial Cells.

Autor: Kotha Lakshmi Narayan P; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA.; Biomedical Sciences PhD Program, Wright State University, Dayton, OH 45435, USA., Readler JM; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA.; Biomedical Sciences PhD Program, Wright State University, Dayton, OH 45435, USA., Alghamri MS; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA.; Biomedical Sciences PhD Program, Wright State University, Dayton, OH 45435, USA., Brockman TL; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA., Yan R; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA., Sharma P; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA., Snitsarev V; Biology Department, Montclair State University, Montclair, NJ 07043, USA., Excoffon KJDA; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA.; Biomedical Sciences PhD Program, Wright State University, Dayton, OH 45435, USA., Kolawole AO; Department of Biological Sciences, Wright State University, Dayton, OH 45435, USA.; Biomedical Sciences PhD Program, Wright State University, Dayton, OH 45435, USA.

Publikováno v: Pathogens (Basel, Switzerland) [Pathogens] 2022 Jan 27; Vol. 11 (2). Date of Electronic Publication: 2022 Jan 27.

MAGI-1 PDZ2 Domain Blockade Averts Adenovirus Infection via Enhanced Proteolysis of the Apical Coxsackievirus and Adenovirus Receptor.

Autor: Alghamri MS; Department of Biological Sciences, Wright State University, Dayton, Ohio, USA.; Department of Neurosurgery, University of Michigan Medical School, Ann Arbor, Michigan, USA., Sharma P; Department of Biological Sciences, Wright State University, Dayton, Ohio, USA., Williamson TL; Department of Biological Sciences, Wright State University, Dayton, Ohio, USA., Readler JM; Department of Biological Sciences, Wright State University, Dayton, Ohio, USA., Yan R; Department of Biological Sciences, Wright State University, Dayton, Ohio, USA., Rider SD Jr; Department of Biochemistry and Molecular Biology, Wright State University, Dayton, Ohio, USA., Hostetler HA; Department of Biochemistry and Molecular Biology, Wright State University, Dayton, Ohio, USA., Cool DR; Department of Pharmacology and Toxicology, Wright State University, Dayton, Ohio, USA., Kolawole AO; Department of Biological Sciences, Wright State University, Dayton, Ohio, USA., Excoffon KJDA; Department of Biological Sciences, Wright State University, Dayton, Ohio, USA.

Publikováno v: Journal of virology [J Virol] 2021 Jun 10; Vol. 95 (13), pp. e0004621. Date of Electronic Publication: 2021 Jun 10.

The coxsackievirus and adenovirus receptor: virological and biological beauty.

Autor: Excoffon KJDA; Biological Sciences, Wright State University, Dayton, OH, USA.; Spirovant Sciences, Inc, Philadelphia, PA, USA.

Publikováno v: FEBS letters [FEBS Lett] 2020 Jun; Vol. 594 (12), pp. 1828-1837. Date of Electronic Publication: 2020 May 09.