Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Excitation & Transport"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Patrick Lewis
Publikováno v:
Essays in Biochemistry
Cellular control of vesicle biology and trafficking is critical for cell viability, with disruption of these pathways within the cells of the central nervous system resulting in neurodegeneration and disease. The past two decades have provided import
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8439e890397fade7ffeba91febd80e
https://doi.org/10.1042/ebc20210034
https://doi.org/10.1042/ebc20210034
Publikováno v:
Biochemical Society Transactions
Electron cryo-microscopy (cryo-EM) is a powerful technique for the structural characterization of biological macromolecules, enabling high-resolution analysis of targets once inaccessible to structural interrogation. In recent years, pharmaceutical c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2136926075cb6bb7627eee845107aec8
https://doi.org/10.1042/bst20210444
https://doi.org/10.1042/bst20210444
Autor:
Shamshad Cockcroft
Publikováno v:
Essays in Biochemistry
Lipids are essential constituents of cellular membranes. Once regarded merely as structural components, lipids have taken centre stage with the discovery of their roles in cell signalling and in the generation of bioactive metabolites. Lipids regulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dad9bf8b2855a501437657d52360f14
http://europepmc.org/articles/PMC8578989
http://europepmc.org/articles/PMC8578989
Publikováno v:
Biochemical Journal
The divalent anion sodium symporter (DASS) family of transporters (SLC13 family in humans) are key regulators of metabolic homeostasis, disruption of which results in protection from diabetes and obesity, and inhibition of liver cancer cell prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175e60252896649a1530256f72da0e7f
http://europepmc.org/articles/PMC8652582
http://europepmc.org/articles/PMC8652582
Publikováno v:
Clinical Science (London, England : 1979)
This review focuses on the most recent advances in the understanding of the electrolyte transport-related mechanisms important for the development of severe inherited renal disorders, autosomal dominant (AD) and recessive (AR) forms of polycystic kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a7b96f4ab345e1f5ec1120fa70518cf
http://europepmc.org/articles/PMC8589009
http://europepmc.org/articles/PMC8589009
Autor:
James M. Birch, A. Quigley
Publikováno v:
Emerging Topics in Life Sciences
Membrane proteins, found at the junctions between the outside world and the inner workings of the cell, play important roles in human disease and are used as biosensors. More than half of all therapeutics directly affect membrane protein function whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fe49810aa5cd96a56864d791b0e2b2
https://doi.org/10.1042/etls20210196
https://doi.org/10.1042/etls20210196
Autor:
Samantha C. Salvage, Hugh R. Matthews, Antony P. Jackson, Zaki F. Habib, Christopher L.-H. Huang
Publikováno v:
Biochemical Society Transactions
Voltage-dependent Na+ channel activation underlies action potential generation fundamental to cellular excitability. In skeletal and cardiac muscle this triggers contraction via ryanodine-receptor (RyR)-mediated sarcoplasmic reticular (SR) Ca2+ relea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef98369dd52edb156f5a7d384fff9cf9
http://europepmc.org/articles/PMC8589445
http://europepmc.org/articles/PMC8589445
Publikováno v:
Biochemical Society Transactions
Chloroplasts are photosynthetic plant organelles descended from a bacterial ancestor. The vast majority of chloroplast proteins are synthesized in the cytosol and then imported into the chloroplast post-translationally. Translocation complexes exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25d2e948ce419da71a53b3f41cb5353f
https://doi.org/10.1042/bst20190274
https://doi.org/10.1042/bst20190274
Autor:
Kristina Ehring, Kay Grobe
Publikováno v:
Biochemical Society Transactions
Vertebrate and invertebrate Hedgehog (Hh) morphogens signal over short and long distances to direct cell fate decisions during development and to maintain tissue homeostasis after birth. One of the most important questions in Hh biology is how such H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd428c144e745aa3cc90a3d0755fda20
https://doi.org/10.1042/bst20210918
https://doi.org/10.1042/bst20210918