Zobrazeno 1 - 10
of 798
pro vyhledávání: '"Excitation/inhibition balance"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Sensory experiences and learning induce long-lasting changes in both excitatory and inhibitory synapses, thereby providing a crucial substrate for memory. However, the co-tuning of excitatory long-term potentiation (eLTP) or depression (eLTD
Externí odkaz:
https://doaj.org/article/643400a33e114c66a411bb1060b69432
Autor:
Vardan Arutiunian, Megha Santhosh, Emily Neuhaus, Heather Borland, Chris Tompkins, Raphael A. Bernier, Susan Y. Bookheimer, Mirella Dapretto, Abha R. Gupta, Allison Jack, Shafali Jeste, James C. McPartland, Adam Naples, John D. Van Horn, Kevin A. Pelphrey, Sara Jane Webb
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Background Most children with Autism Spectrum Disorder (ASD) have co-occurring language impairments and some of these autism-specific language difficulties are also present in their non-autistic first-degree relatives. One of the possible ne
Externí odkaz:
https://doaj.org/article/2a915911ffab4dd7894744918d7e1457
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionSocial anxiety disorder (SAD) is a prevalent psychiatric condition characterized by an intense fear of and avoidance of social situations. Traditional assessment methods for SAD primarily rely on subjective self-report questionnaires and
Externí odkaz:
https://doaj.org/article/786ec3e155b741a69b06926290c3a15d
Publikováno v:
eLife, Vol 13 (2024)
A finely tuned balance between excitation and inhibition (E/I) is essential for proper brain function. Disruptions in the GABAergic system, which alter this equilibrium, are a common feature in various types of neurological disorders, including autis
Externí odkaz:
https://doaj.org/article/f69a5cb056744de889f81a23244c96d7
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
During postnatal brain development, maintaining a delicate balance between excitation and inhibition (E/I) is essential for the precise formation of neuronal circuits. The K+/cl− cotransporter 2 (KCC2) is instrumental in this process, and its dysre
Externí odkaz:
https://doaj.org/article/8eae5c564a214807a6c0dd9f0cd4c90d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Retinitis Pigmentosa (RP) is a heterogenous group of inherited disorder, and its progression not only affects the retina but also the primary visual cortex. This manifests imbalances in the excitatory and inhibitory neurotransmission. Here, we invest
Externí odkaz:
https://doaj.org/article/e7f2dfa1391a4cebbff3b9b8c299a8c6
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionThe prevalence of Alzheimer’s disease (AD) is significantly gender-differentiated, with the number of female AD patients far exceeding that of males, accounting for two-thirds of the total prevalence. Although postmenopausal AD mice hav
Externí odkaz:
https://doaj.org/article/ace4fa6428cf408cad290180456f0db0
Publikováno v:
International Journal of Nanomedicine, Vol Volume 19, Pp 2025-2038 (2024)
Pingyang Ke,1,* Jing Liu,1,2,* Chengzhi Chen,3,* Sen Luo,3,* Huiwen Gu,3,* Juan Gu,4 Yan Liu,1 Yuanlin Ma,1 Yuan Meng,1 Liqin Hu,1 Xin Tian,1 Fei Xiao1 1Department of Neurology, The First Affiliated Hospital of Chongqing Medical U
Externí odkaz:
https://doaj.org/article/e7ec833007b74fd4a43de5aae90ff830
Autor:
Eva-Maria Weiss, Debarpan Guhathakurta, Aneta Petrušková, Verena Hundrup, Martin Zenker, Anna Fejtová
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
RASopathies are a group of genetic disorders caused by mutations in genes encoding components and regulators of the RAS/MAPK signaling pathway, resulting in overactivation of signaling. RASopathy patients exhibit distinctive facial features, cardiopa
Externí odkaz:
https://doaj.org/article/6614b79375604446a8d3f40b06280d1f
Autor:
Shane D. McKeon, Maria I. Perica, Ashley C. Parr, Finnegan J. Calabro, Will Foran, Hoby Hetherington, Chan-Hong Moon, Beatriz Luna
Publikováno v:
Developmental Cognitive Neuroscience, Vol 66, Iss , Pp 101373- (2024)
Adolescence has been hypothesized to be a critical period for the development of human association cortex and higher-order cognition. A defining feature of critical period development is a shift in the excitation: inhibition (E/I) balance of neural c
Externí odkaz:
https://doaj.org/article/8e6630506bb944f29972cf17d08fe2b5