Polysorbate 20 alters the oral bioavailability of etoposide in wild type and mdr1a deficient Sprague-Dawley rats

Autor: Bente Steffansen, René Holm, Christoffer Bundgaard, Ahmed A. Abdulhussein Al-Ali, Carsten Uhd Nielsen, Jeffrey Rong Chao Quach

Publikováno v: Al-Ali, A A A, Quach, J R C, Bundgaard, C, Steffansen, B, Holm, R & Nielsen, C U 2018, ' Polysorbate 20 alters the oral bioavailability of etoposide in wild type and mdr1a deficient Sprague-Dawley rats ', International Journal of Pharmaceutics, vol. 543, no. 1-2, pp. 352–360 . https://doi.org/10.1016/j.ijpharm.2018.04.006

The aim of the present work was to investigate the ability of nonionic surfactants to increase the oral absorption of the P-glycoprotein substrate etoposide in vitro and in vivo. Intestinal absorption was investigated by studying bidirectional permea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7591273955bc373d09509af91457dcff
https://doi.org/10.1016/j.ijpharm.2018.04.006

Safe excipient exposure in neonates and small children:protocol for the SEEN project

Autor: Valeur, Kristine Svinning, Hertel, Steen Axel, Lundstrøm, Kaare Engell, Holst, Helle

Publikováno v: Valeur, K S, Hertel, S A, Lundstrøm, K E & Holst, H 2017, ' Safe excipient exposure in neonates and small children : protocol for the SEEN project ', Danish Medical Journal, vol. 64, no. 2, A5324 . < http://ugeskriftet.dk/dmj/safe-excipient-exposure-neonates-and-small-children-protocol-seen-project >

INTRODUCTION: The pharmacokinetics of excipients in neonates differs from that of older children. In a recent pan--European survey, two thirds of neonates received at least one potentially harmful excipient, such as ethanol and benzoates. The content

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2751::cb3819c6958a5f324e5341974b93f872
https://curis.ku.dk/portal/da/publications/safe-excipient-exposure-in-neonates-and-small-children(b362d623-aa50-4868-98d1-a98af234fd2f).html

Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo

Autor: Catherine Anne-Marie Curdy, Aarti Naik, Ingo Alberti, Richard H. Guy, Yogeshvar N. Kalia

Publikováno v: International Journal of Pharmaceutics, Vol. 271, No 1-2 (2004) pp. 251-6

The objective of the present work was to investigate the effect of formulation excipients on human stratum corneum (SC) barrier function in vivo. Two formulations, an ointment and an oil-in-water cream, were applied to the skin of human volunteers un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39324f140a362389069e5c12cef43d81
https://pubmed.ncbi.nlm.nih.gov/15129992

Interventions for preventing occupational irritant hand dermatitis

Autor: Cathy Bennett, Andrea Bauer, Swen Malthe John, Judit Lukács, Daan Dittmar, Hywel C Williams, Marielouise Schuttelaar, Peter Elsner, Henriette Rönsch

Publikováno v: Scopus-Elsevier
The Cochrane Library

BACKGROUND: Occupational irritant hand dermatitis (OIHD) causes significant functional impairment, disruption of work, and discomfort in the working population. Different preventive measures such as protective gloves, barrier creams and moisturisers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0225ec32858be9bcda1f09e6a44fbe5
http://www.scopus.com/inward/record.url?eid=2-s2.0-77954963394&partnerID=MN8TOARS