Zobrazeno 1 - 10
of 801
pro vyhledávání: '"Ex-vivo permeation"'
Publikováno v:
Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-17 (2024)
Abstract Background This study aimed to formulate solid self-nanoemulsifying drug delivery systems (SNEDDS) for nimodipine (NIM). The selection of Cremophor RH 40, Lipoxol 300, and PEG 400 as oil, surfactant, and co-surfactant was based on solubility
Externí odkaz:
https://doaj.org/article/58eb59a022d242058197184bdad5d4e8
Publikováno v:
Iraqi Journal of Pharmaceutical Sciences, Vol 33, Iss 3 (2024)
Lasmiditan (LAS) was formulated as a nanoemulsion based in situ gel (NEIG)with the aim of improving its oral bioavailability via application intranasally. The solubility of LAS in oils, emulsifiers, and co-emulsifiers was determined to identify nan
Externí odkaz:
https://doaj.org/article/69b89c3e8a0e41d0a835b28b0b3dc6fe
Autor:
Sophie Luise Meiser, Jonas Pielenhofer, Ann-Kathrin Hartmann, Lara Stein, Jule Dettweiler, Stephan Grabbe, Markus P. Radsak, Peter Langguth
Publikováno v:
Frontiers in Drug Delivery, Vol 4 (2024)
Transcutaneous delivery systems bear several advantages over conventional needle-based injections. Considering the low bioavailability and poor water-solubility of imiquimod, a manufacturing process has been developed to incorporate imiquimod as susp
Externí odkaz:
https://doaj.org/article/84b0248e65984210829b7ef189071e4b
Autor:
Omar Awad Alsaidan, Ameeduzzafar Zafar, Rayan Hamood Al-Ruwaili, Mohd Yasir, Sami I. Alzarea, Aseel Awad Alsaidan, Lubhan Singh, Mohammad Khalid
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 604-617 (2023)
AbstractNiosomes (NS) are the promising and novel carrier of the drug for effective transdermal delivery. Apigenin (AN) is a natural bioactive compound and has various pharmacological activities. AN is poorly water soluble which directly affects ther
Externí odkaz:
https://doaj.org/article/57ebe2cc1a4042c380911440312f85f4
Autor:
Fahad Pervaiz, Ayesha Saba, Haya Yasin, Manal Buabeid, Sobia Noreen, Abida Kalsoom Khan, Ghulam Murtaza
Publikováno v:
Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 108-119 (2023)
AbstractParoxetine is not suitable for oral administration due to its extensive first-pass metabolism, thus resulting in less bioavailability. This study aimed to prepare novel paroxetine-loaded solid lipid nanoparticles (SLNs) based sustained-releas
Externí odkaz:
https://doaj.org/article/84c14c05c3d44ea8b0018d47c84c443a
Autor:
Mona M. Shahien, Alia Alshammari, Somaia Ibrahim, Enas Haridy Ahmed, Hanan Abdelmawgoud Atia, Hemat A. Elariny, Marwa H. Abdallah
Publikováno v:
Gels, Vol 10, Iss 9, p 608 (2024)
Sulpiride (Sul) is a medication that blocks dopamine D2 receptors. It is used to treat gastrointestinal disturbances and has antipsychotic effects depending on the dose given. Sulpiride is subject to P-glycoprotein efflux, resulting in limited bioava
Externí odkaz:
https://doaj.org/article/fd2726f887214c41b07c5c55fffdcdb4
Autor:
Farhath Fathima A, Imran Khan, Mohammed Irfhan N, Zaheer Ahmed N, Noman Anwar, Mohd Shahnawaz Khan, Dharmendra Kumar Yadav, Shariq Shamsi, Anas Shamsi
Publikováno v:
Heliyon, Vol 10, Iss 3, Pp e25284- (2024)
Ustukhuddūs (Lavandula stoechas L.) has been extensively used orally and topically in treating various neurological disorders, including dementia. The optimum potential of traditional dosage forms of Ustukhuddūs is limited for various reasons. Tran
Externí odkaz:
https://doaj.org/article/1dfa71f68b4b4d429e694eac13a84396
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 1259-1280 (2023)
Abeer S Hassan,1 Amal Hofni,2 Mohammed AS Abourehab,3 Iman AM Abdel-Rahman4 1Department of Pharmaceutics, Faculty of Pharmacy, South Valley University, Qena, Egypt; 2Department of Pharmacology and Toxicology, Faculty of Pharmacy, South Valley Univers
Externí odkaz:
https://doaj.org/article/64e435877eac4d0b81488fa2a248a76c
Autor:
Reem Alfaris, Khalid K Al-Kinani
Publikováno v:
مجلة كلية الطب, Vol 65, Iss 3 (2023)
Background: Prednisolone acetate is an ester form of prednisolone. It is used topically as an ophthalmic suspension to treat many inflammatory ocular conditions, where its absorption from suspension is highly variable and has poor dose accuracy. Ob
Externí odkaz:
https://doaj.org/article/693cd6e5a34f4f0aba72aba68f03b225
Autor:
Jamal Moideen Muthu Mohamed, Barkat A Khan, Vijaya Rajendran, Mohamed El-Sherbiny, Gamal Othman, Abdulrahman Bashir Ahmed Hussamuldin, Rasha Hamed Al-Serwi
Publikováno v:
Saudi Pharmaceutical Journal, Vol 30, Iss 11, Pp 1603-1611 (2022)
This study was performed with the main objective of formulating and evaluating the potential of ethosomesl gel (Etho gel) to deliver nimodipine (NiM) for cardiovascular disease, a potent water insoluble anti-hypertensive drug via skin to reach the de
Externí odkaz:
https://doaj.org/article/67cd41227bfd4be7809183e2df52cfe8