Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ewoud R.E. Schmidt"'
Autor:
Franck Polleux, Bongjin Shin, Anne M. Delany, Sun-Kyeong Lee, Justine V. Kupferman, Ewoud R.E. Schmidt
Publikováno v:
J Bone Miner Res
The Rac1-specific guanosine triphosphatase (GTPase)-activating protein Slit-Robo GAP2 (Srgap2) is dramatically upregulated during RANKL-induced osteoclastogenesis. Srgap2 interacts with the cell membrane to locally inhibit activity of Rac1. In this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44ada18c1c7f7bd5276f85e0137dc96
https://doi.org/10.1002/jbmr.3945
https://doi.org/10.1002/jbmr.3945
Autor:
Jacob B. Dahan, Franck Polleux, Mario Dipoppa, Randy M. Bruno, Elizabeth M. C. Hillman, Ewoud R.E. Schmidt, Mauro M. Monsalve-Mercado, Jung M. Park, Hanzhi T. Zhao, Amélie Lejeune, Kenneth D. Miller, Chris C. Rodgers
Publikováno v:
Nature
The cognitive abilities that characterize humans are thought to emerge from unique features of the cortical circuit architecture of the human brain, which include increased cortico–cortical connectivity. However, the evolutionary origin of these ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::580c94ba48ec06619f0ff10745b13e76
https://europepmc.org/articles/PMC9161439/
https://europepmc.org/articles/PMC9161439/
Autor:
Laurens M. Grossouw, Alain Chédotal, Marieke G. Verhagen, Ewoud R.E. Schmidt, Jean-François Cloutier, Anna A. De Ruiter, Juan Antonio Moreno-Bravo, Christiaan van der Meer, Youri Adolfs, Mateja Rybiczka-Tesulov, Emilie Dumontier, R. Jeroen Pasterkamp, Divya Raj, O. Dudukcu, Mark H. Broekhoven, Sara Brignani
Publikováno v:
Neuron
The midbrain dopamine (mDA) system is composed of molecularly and functionally distinct neuron subtypes that mediate specific behaviors and show select disease vulnerability, including in Parkinson's disease. Despite progress in identifying mDA neuro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ac1046bf38f387bfc919ca26942c5d
Autor:
Franck Polleux, Randy M. Bruno, Hanzhi T. Zhao, Ewoud R.E. Schmidt, Elizabeth M. C. Hillman, Jung M. Park, Jacob B. Dahan, Chris C. Rodgers
SUMMARYThe remarkable cognitive abilities characterizing humans are thought to emerge from our unique features of cortical circuit architecture, including increased feedforward and feedback connectivity. However, our understanding of the evolutionary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57632ef235d25866cf608fca23517963
https://doi.org/10.1101/852970
https://doi.org/10.1101/852970
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports
Scientific Reports
Human-specific gene duplications (HSGD) have recently emerged as key modifiers of brain development and evolution. However, the molecular mechanisms underlying the function of HSGDs remain often poorly understood. In humans, a truncated duplication o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3162e85b6cb5ac7c025e22756835a560
Autor:
Franck Polleux, Cécile Charrier, Matteo Fossati, Ewoud R.E. Schmidt, David Stroebel, Rocco Pizzarelli, Justine V. Kupferman
Publikováno v:
Neuron. 91:356-369
The proper function of neural circuits requires spatially and temporally balanced development of excitatory and inhibitory synapses. However, the molecular mechanisms coordinating excitatory and inhibitory synaptogenesis remain unknown. Here we demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b458f015aefaead09e131b9afb858f
https://doi.org/10.1016/j.neuron.2016.06.013
https://doi.org/10.1016/j.neuron.2016.06.013
Publikováno v:
Pharmacology, Biochemistry and Behavior, 162, 29. Elsevier Inc.
The habenula is an evolutionarily conserved brain region comprising bilaterally paired nuclei that plays a key role in processing reward information and mediating aversive responses to negative stimuli. An important aspect underlying habenula functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782715051e79a69743f9bd7519d99290
https://dspace.library.uu.nl/handle/1874/361477
https://dspace.library.uu.nl/handle/1874/361477
Autor:
Wouter G. Staal, Eric A. M. Hennekam, René S. Kahn, H. van Engeland, E. van Daalen, Roel A. Ophoff, Jacob A. S. Vorstman, Esther Janson, Ewoud R.E. Schmidt, R.J. Pasterkamp, J.P.H. Burbach, G.R. Jalali, Beverly S. Emanuel, B. van der Zwaag, M. de Jonge
Publikováno v:
Molecular Psychiatry. 16:442-451
Recent studies have shown that more than 10% of autism cases are caused by de novo structural genomic rearrangements. Given that some heritable copy number variants (CNVs) have been observed in patients as well as in healthy controls, to date little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b0d669908938e608116dc6eaa0ead49
https://doi.org/10.1038/mp.2010.26
https://doi.org/10.1038/mp.2010.26
Autor:
Eero Vasar, R.J. Pasterkamp, Linda J. Richards, Sara Brignani, Ewoud R.E. Schmidt, Sharon M. Kolk, Kersti Lilleväli, Youri Adolfs, Amber Lee Skye Donahoo, Jeroen Demmers, Suzanne Lemstra, Domna Karagogeos, Marina Vidaki
Publikováno v:
Neuron, 83(2), 372-387. Cell Press
Neuron, 83, 2, pp. 372-87
Neuron, 83, 372-87
Neuron
Neuron, 83, 2, pp. 372-87
Neuron, 83, 372-87
Neuron
SummaryA dominant feature of neural circuitry is the organization of neuronal projections and synapses into specific brain nuclei or laminae. Lamina-specific connectivity is controlled by the selective expression of extracellular guidance and adhesio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6691e00d107d10d52ad84a820048a6b9
https://doi.org/10.1016/j.neuron.2014.05.036
https://doi.org/10.1016/j.neuron.2014.05.036
Autor:
Gustavo Turecki, Richard Ryan, M. J. J. Daubaras, S. V. Yogendran, Cecilia Flores, Matthew Pokinko, Alanna Grant, Tak Pan Wong, Helen M. Cooper, Ewoud R.E. Schmidt, Paul Krimpenfort, R.J. Pasterkamp, Bruno Giros, Conrad Eng, Colleen Manitt, François Tronche, Eric J. Nestler, Bryan Kolb, Juan Pablo Lopez, Angélica Torres-Berrío
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Nature Pub. Group, 2013, 3, pp.e338. ⟨10.1038/tp.2013.105⟩
Translational Psychiatry, 2013, 3, pp.e338. ⟨10.1038/tp.2013.105⟩
Translational Psychiatry, Nature Pub. Group, 2013, 3, pp.e338. ⟨10.1038/tp.2013.105⟩
Translational Psychiatry, 2013, 3, pp.e338. ⟨10.1038/tp.2013.105⟩
International audience; Adolescence is a period of heightened susceptibility to psychiatric disorders of medial prefrontal cortex (mPFC) dysfunction and cognitive impairment. mPFC dopamine (DA) projections reach maturity only in early adulthood, when
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aa66036f1cd72530365719c5aa7bb05
https://hal.archives-ouvertes.fr/hal-01542331
https://hal.archives-ouvertes.fr/hal-01542331