Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ewelina Pilny"'
Autor:
Ewelina Pilny, Justyna Czapla, Alina Drzyzga, Ryszard Smolarczyk, Sybilla Matuszczak, Magdalena Jarosz-Biej, Łukasz Krakowczyk, Tomasz Cichoń
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Background Adipose-derived stromal cells (ADSCs) demonstrate ability to promote tissue healing and down-regulate excessive inflammation. ADSCs have been used to treat critical limb ischemia in preclinical and clinical trials, but still, ther
Externí odkaz:
https://doaj.org/article/729fd186e8634bb1a04a6c16eb76cb00
Autor:
Justyna Czapla, Alina Drzyzga, Sybilla Matuszczak, Tomasz Cichoń, Marek Rusin, Magdalena Jarosz-Biej, Ewelina Pilny, Ryszard Smolarczyk
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionTargeting tumor vasculature is an efficient weapon to fight against cancer; however, activation of alternative pathways to rebuild the disrupted vasculature leads to rapid tumor regrowth. Immunotherapy that exploits host immune cells to e
Externí odkaz:
https://doaj.org/article/f9049cc6dd234f21be06968ce1421094
Autor:
Natalia Kułach, Ewelina Pilny, Tomasz Cichoń, Justyna Czapla, Magdalena Jarosz-Biej, Marek Rusin, Alina Drzyzga, Sybilla Matuszczak, Stanisław Szala, Ryszard Smolarczyk
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Due to immunosuppressive properties and confirmed tropism towards cancer cells mesenchymal stromal cells (MSC) have been used in many trials. In our study we used these cells as carriers of IL-12 in the treatment of mice with primary and met
Externí odkaz:
https://doaj.org/article/bcd4d466f3a84e96830b0f5ae3e9063f
Autor:
Sybilla Matuszczak, Krzysztof Szczepanik, Aleksandra Grządziel, Alina Drzyzga, Tomasz Cichoń, Justyna Czapla, Ewelina Pilny, Ryszard Smolarczyk
Publikováno v:
Biomedicines, Vol 11, Iss 6, p 1773 (2023)
Radiotherapy (RT) is one of the main treatments for head and neck squamous cell carcinomas (HNSCCs). Unfortunately, radioresistance is observed in many cases of HNSCCs. The effectiveness of RT depends on both the direct effect inducing cell death and
Externí odkaz:
https://doaj.org/article/d5d90e6bd73c400a86b79161a2370229
Autor:
Justyna Czapla, Sybilla Matuszczak, Klaudia Kulik, Ewa Wiśniewska, Ewelina Pilny, Magdalena Jarosz-Biej, Ryszard Smolarczyk, Tomasz Sirek, Michał Oskar Zembala, Marian Zembala, Stanisław Szala, Tomasz Cichoń
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-11 (2019)
Abstract Background Adipose tissue-derived mesenchymal stromal cells (ASCs) have been shown to exhibit some promising properties of their use in regenerative medicine as advanced therapy medicinal products (ATMP). However, different sources of their
Externí odkaz:
https://doaj.org/article/f32f1a60b8e9465a8e8198df4e296c46
Autor:
Ewelina Pilny, Ryszard Smolarczyk, Magdalena Jarosz-Biej, Alina Hadyk, Agnieszka Skorupa, Mateusz Ciszek, Łukasz Krakowczyk, Natalia Kułach, Danuta Gillner, Maria Sokół, Stanisław Szala, Tomasz Cichoń
Publikováno v:
Stem Cell Research & Therapy, Vol 10, Iss 1, Pp 1-20 (2019)
Abstract Background Adipose-derived mesenchymal stromal cells (ADSCs) are multipotent stromal cells. The cells secrete a number of cytokines and growth factors and show immunoregulatory and proangiogenic properties. Their properties may be used to re
Externí odkaz:
https://doaj.org/article/900cab922cac41a3971730f47e4babf2
Autor:
Ryszard Smolarczyk, Tomasz Cichoń, Ewelina Pilny, Magdalena Jarosz-Biej, Aleksandra Poczkaj, Natalia Kułach, Stanisław Szala
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Vascular disrupting agents as DMXAA inhibit tumor growth only for a short period of time followed by rapid tumor regrowth. Among others, hypoxia and presence of transcription factor HIF-1α are responsible for tumors regrowth. The aim of our
Externí odkaz:
https://doaj.org/article/2ccfc0f6326849a7bf8f9fa6b0266d41
Autor:
Magdalena Jarosz-Biej, Ryszard Smolarczyk, Tomasz Cichoń, Alina Drzyzga, Justyna Czapla, Zbigniew Urbaś, Ewelina Pilny, Sybilla Matuszczak, Piotr Wojcieszek
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4585 (2020)
Radiotherapy (RT) is one of the major methods of cancer treatment. RT destroys cancer cells, but also affects the tumor microenvironment (TME). The delicate balance between immunomodulation processes in TME is dependent, among other things, on a spec
Externí odkaz:
https://doaj.org/article/8980afd46eab4bb683583b118ef7f2eb
Autor:
JUSTYNA CZAPLA, ALINA DRZYZGA, SYBILLA MATUSZCZAK, EWELINA PILNY, TOMASZ CICHOŃ, KRZYSZTOF STOJECKI, RYSZARD SMOLARCZYK
Publikováno v:
Anticancer Research. 42:4763-4772
Numerous studies have demonstrated an anti-cancer action of plant-derived polyphenols. Their action is mainly related to antioxidant, anti-inflammatory, immunomodulatory and inhibitory properties. It is expected that proper composition of nutrition f
Autor:
Smolarczyk, Sybilla Matuszczak, Krzysztof Szczepanik, Aleksandra Grządziel, Alina Drzyzga, Tomasz Cichoń, Justyna Czapla, Ewelina Pilny, Ryszard
Publikováno v:
Biomedicines; Volume 11; Issue 6; Pages: 1773
Radiotherapy (RT) is one of the main treatments for head and neck squamous cell carcinomas (HNSCCs). Unfortunately, radioresistance is observed in many cases of HNSCCs. The effectiveness of RT depends on both the direct effect inducing cell death and