Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Ewelina Madej"'
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Akademický článek
Deciphering the Functional Role of RIPK4 in Melanoma
Autor: Ewelina Madej, Damian Ryszawy, Anna A. Brożyna, Malgorzata Czyz, Jaroslaw Czyz, Agnieszka Wolnicka-Glubisz
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 21, p 11504 (2021)
The receptor-interacting protein kinase 4 (RIPK4) plays an important role in the development and maintenance of various tissues including skin, but its role in melanoma has not been reported. Using patient-derived cell lines and clinical samples, we
Externí odkaz: https://doaj.org/article/fe5554cd6a21484a979e22f93da62d28
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2
Vemurafenib and Dabrafenib Downregulates RIPK4 Level
Autor: Ewelina Madej, Anna A. Brożyna, Agnieszka Adamczyk, Norbert Wronski, Agnieszka Harazin-Lechowska, Anna Muzyk, Krzysztof Makuch, Michal Markiewicz, Janusz Rys, Agnieszka Wolnicka-Glubisz
Publikováno v: Cancers
Volume 15
Issue 3
Pages: 918
Vemurafenib and dabrafenib are BRAF kinase inhibitors (BRAFi) used for the treatment of patients with melanoma carrying the V600E BRAF mutation. However, melanoma cells develop resistance to both drugs when used as monotherapy. Therefore, mechanisms
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f735074edcabce1cbe4c7a334e59c0
https://doi.org/10.3390/cancers15030918
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4
The role of RIPK4 in epidermis physiology
Autor: Agnieszka, Wolnicka-Głubisz, Ewelina, Madej, Anna, Lisek
Publikováno v: Postepy biochemii. 67(1)
Proteins which regulate morphogenesis of the epidermis ensure its proper construction and function and mutations or abnormal expression of those proteins impact epidermal function. One recently described protein is Receptor Interacting Serine/Threoni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e615e65c12b374554aa655c75682dd0
https://pubmed.ncbi.nlm.nih.gov/34378900
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5
p38 but not p53 is responsible for UVA-induced MCPIP1 expression
Autor: Marta Smejda, Anna Adamczyk, Lukasz Skalniak, Agnieszka Cierniak, Piotr Konieczny, Agnieszka Wolnicka-Glubisz, Ewelina Madej
Publikováno v: Mechanisms of ageing and development. 172
MCPIP1 (Monocyte Chemotactic Protein-1 Induced Protein) is an important regulator of inflammation and cell apoptosis, but its role in UVA-induced stress response in the epidermis has never been studied. We have found that moderate apoptosis-inducing
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf0e2652953b698017d5a0ceced07244
https://pubmed.ncbi.nlm.nih.gov/29103983
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6
PDMS substrate stiffness affects the morphology and growth profiles of cancerous prostate and melanoma cells
Autor: Joanna Raczkowska, Josef Sepitka, Szymon Prauzner-Bechcicki, Jakub Rysz, Andrzej Budkowski, Ewelina Madej, Jaroslav Lukes, Kamil Awsiuk, Joanna Pabijan, Andrzej Bernasik, Małgorzata Lekka
A deep understanding of the interaction between cancerous cells and surfaces is particularly important for the design of lab-on-chip devices involving the use of polydimethylsiloxane (PDMS). In our studies, the effect of PDMS substrate stiffness on m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02285b98d6cebcda53bb35417a230a5f
http://ruj.uj.edu.pl/xmlui/handle/item/12848
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