Výsledky vyhledávání - "Ewelina Juszczyk"

Akademický článek

Development of a Formulation and In Vitro Evaluation of a Pulmonary Drug Delivery System for a Novel Janus Kinase (JAK) Inhibitor, CPL409116

Autor: Aleksandra Rzewińska, Jakub Szlęk, Damian Dąbrowski, Ewelina Juszczyk, Katarzyna Mróz, Heikki Räikkönen, Mia Siven, Maciej Wieczorek, Przemysław Dorożyński

Publikováno v: Pharmaceutics, Vol 16, Iss 9, p 1157 (2024)

The pursuit of targeted therapies for cytokine-dependent diseases has led to the discovery of Janus kinase (JAK) inhibitors, a promising class of drugs. Among them, CPL409116, a selective dual JAK and rho-associated protein kinase inhibitor (ROCK), h

Externí odkaz: https://doaj.org/article/6049c0b9f7b84a35a5814f9bec6fdeb6

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Akademický článek

Development and Bio-Predictive Evaluation of Biopharmaceutical Properties of Sustained-Release Tablets with a Novel GPR40 Agonist for a First-in-Human Clinical Trial

Autor: Ewelina Juszczyk, Kamil Kisło, Paweł Żero, Ewa Tratkiewicz, Maciej Wieczorek, Jadwiga Paszkowska, Grzegorz Banach, Marcela Wiater, Dagmara Hoc, Grzegorz Garbacz, Jaroslaw Sczodrok, Dorota Danielak

Publikováno v: Pharmaceutics, Vol 13, Iss 6, p 804 (2021)

Sustained-release (SR) formulations may appear advantageous in first-in-human (FIH) study of innovative medicines. The newly developed SR matrix tablets require prolonged maintenance of API concentration in plasma and should be reliably assessed for

Externí odkaz: https://doaj.org/article/2c388692b34c45d5a425d96b77ef910b

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Development and Bio-Predictive Evaluation of Biopharmaceutical Properties of Sustained-Release Tablets with a Novel GPR40 Agonist for a First-in-Human Clinical Trial

Autor: Maciej Wieczorek, Grzegorz Banach, Paweł Żero, Ewa Tratkiewicz, Marcela Wiater, Grzegorz Garbacz, Dorota Danielak, Jadwiga Paszkowska, Ewelina Juszczyk, Kamil Kisło, Jaroslaw Sczodrok, Dagmara Hoc

Publikováno v: Pharmaceutics
Volume 13
Issue 6
Pharmaceutics, Vol 13, Iss 804, p 804 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f6faacc4f6c060123019084ce7689b
https://pubmed.ncbi.nlm.nih.gov/34071286

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Spatiotemporal Analysis of Hydration Mechanism in Sodium Alginate Matrix Tablets

Autor: Władysław P. Węglarz, Piotr Kulinowski, Ewelina Juszczyk, Ewelina Baran, Przemysław Dorożyński, Josep M. Suñé-Negre, Artur Birczyński, Dorota Majda, Pilar Pérez-Lozano, Encarna García-Montoya

Publikováno v: Materials
Dipòsit Digital de la UB
Universidad de Barcelona
Materials, Vol 14, Iss 646, p 646 (2021)
Volume 14
Issue 3

Methods of spatiotemporal characterization of nonequilibrated polymer based matrices are still immature and imperfect. The purpose of the study was to develop the methodology for the spatiotemporal characterization of water transport and properties i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6516698c88e4448597911952183f9b9
https://pubmed.ncbi.nlm.nih.gov/33573366

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Hydration Patterns in Sodium Alginate Polymeric Matrix Tablets The Result of Drug Substance Incorporation

Autor: Encarna García-Montoya, Ewelina Baran, Władysław P. Węglarz, Jolanta Klaja, A. Birczyński, Piotr Kulinowski, Przemysław Dorożyński, Dorota Majda, Ewelina Juszczyk

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Materials
Volume 14
Issue 21
Materials, Vol 14, Iss 6531, p 6531 (2021)

The purpose was to show, using destructive/nondestructive methods, that the interplay between water, tablet structure, and composition determine the unique spatiotemporal hydration pattern of polymer-based matrices. The tablets containing a 1:1 w/w m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6d47d288495706efc38e30422f239a
http://hdl.handle.net/2445/181477

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The Relationship Between the Evolution of an Internal Structure and Drug Dissolution from Controlled-Release Matrix Tablets

Autor: Władysław P. Węglarz, Aleksander Mendyk, Ewelina Juszczyk, Piotr Kulinowski, Przemysław Dorożyński, Renata Jachowicz, Wiktor Hudy

In the last decade, imaging has been introduced as a supplementary method to the dissolution tests, but a direct relationship of dissolution and imaging data has been almost completely overlooked. The purpose of this study was to assess the feasibili

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5fa9c2fa44ee3052e0a52ab97fa0e4
https://ruj.uj.edu.pl/xmlui/handle/item/118693

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Geometry of modified release formulations during dissolution-Influence on performance of dosage forms with diclofenac sodium

Autor: Witold Jamróz, Piotr Kulinowski, Ewelina Juszczyk, Przemysław Dorożyński

The objectives of the work included: presentation of magnetic resonance imaging (MRI) and fractal analysis based approach to comparison of dosage forms of different composition, structure, and assessment of the influence of the compositional factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52d34af5199b26328e3f6cd5c0d379f8
https://ruj.uj.edu.pl/xmlui/handle/item/123502

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