Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ewelina Gumbarewicz"'
Autor:
Marta Kluz-Barłowska, Tomasz Kluz, Wiesław Paja, Jaromir Sarzyński, Edyta Barnaś, Monika Łączyńska-Madera, Yaroslav Shpotyuk, Ewelina Gumbarewicz, Bartosz Klebowski, Jozef Cebulski, Joanna Depciuch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Patients with high-grade ovarian cancer have a poor prognosis, thus effective treatment remains an unmet medical issue of high importance. Moreover, finding the reason for resistance to cisplatin is a crucial task for the improvement of anti
Externí odkaz:
https://doaj.org/article/a7c0c38e13584e7e9aca13c9af25745b
Publikováno v:
Molecules, Vol 25, Iss 9, p 2173 (2020)
Green tea contains a variety of biologically active constituents that are widely used in the pharmaceutical and food industries. Among them, simple catechins constitute a major group of compounds that is primarily responsible for the high biologic ac
Externí odkaz:
https://doaj.org/article/f91be2d528fc460297f02b8313942147
Autor:
Anna Wawruszak, Jarogniew J Luszczki, Aneta Grabarska, Ewelina Gumbarewicz, Magdalena Dmoszynska-Graniczka, Krzysztof Polberg, Andrzej Stepulak
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143013 (2015)
Histone deacetylase inhibitors (HDIs) are promising anticancer drugs, which inhibit proliferation of a wide variety of cancer cells including breast carcinoma cells. In the present study, we investigated the influence of valproic acid (VPA) and suber
Externí odkaz:
https://doaj.org/article/2f8bcb318c2349a18b8159cbdcb5e3c9
Publikováno v:
International Journal of Molecular Sciences. 23:15545
Inflammation is a protective reaction of the innate immune system as a response to imbalances caused by a specific stimulus, a disease or a pathogen. A prolonged inflammatory condition may lead to the development of metabolic syndrome, which affects
Autor:
Victoria I. Bunik, Toshihiro Obata, Artem V. Artiukhov, Vasily A. Aleshin, Alisdair R. Fernie, Alexey V. Kazantsev, Thilo Kähne, Aneta Grabarska, Ewelina Gumbarewicz, Nikolay V. Lukashev, Andrzej Stepulak
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-22 (2020)
Scientific Reports
Scientific Reports
The biological significance of the DHTKD1-encoded 2-oxoadipate dehydrogenase (OADH) remains obscure due to its catalytic redundancy with the ubiquitous OGDH-encoded 2-oxoglutarate dehydrogenase (OGDH). In this work, metabolic contributions of OADH an
Autor:
Shakti Upadhyay, Ewelina Gumbarewicz, Kazimierz Głowniak, Ewa Nowosadzka, Andrzej Stepulak, Aneta Grabarska, Gregoire Audo, Lidia Czernicka, Agata Jarząb, Wirginia Kukula-Koch, Jarogniew J. Łuszczki
Publikováno v:
Phytotherapy Research. 32:933-942
Three curcuminoids: bisdemethoxycurcumin, demethoxycurcumin, and curcumin from turmeric were successfully separated by a high capacity solvent system composed of heptane: chloroform: methanol: water mixture (5: 6: 3: 2 v/v/v/v) tailored for centrifug
Autor:
Małgorzata Guz, Andrzej Stepulak, Jarogniew J. Łuszczki, Ewelina Gumbarewicz, Krzysztof Polberg, Agata Jarząb
Publikováno v:
Anticancer Research. 37:1067-1074
BACKGROUND/AIM The aim of this study was to assess the anticancer effect and the type of pharmacologic drug-drug interaction of cisplatin (CDDP) and histone deacetylase inhibitors (HDIs) combined treatment on the rhabdomyosarcoma cell line. MATERIALS
Autor:
Karolina Okła, Ewelina Gumbarewicz, Artur Bocian, Witold Jeleniewicz, Anna Wawruszak, Estera Okon, Adolfo Rivero-Müller, Jolanta Smok-Kalwat, Andrzej Stepulak, Marta Halasa, Jakub Czapinski
Publikováno v:
Cancer Management and Research
Anna Wawruszak,1 Ewelina Gumbarewicz,1 Estera Okon,1 Witold Jeleniewicz,1 Jakub Czapinski,1,2 Marta Halasa,1 Karolina Okla,3,4 Jolanta Smok-Kalwat,5 Artur Bocian,6 Adolfo Rivero-Muller,1,7,* Andrzej Stepulak1,* 1Department of Biochemistry and Molecul
Publikováno v:
Molecules
Volume 25
Issue 9
Molecules, Vol 25, Iss 2173, p 2173 (2020)
Volume 25
Issue 9
Molecules, Vol 25, Iss 2173, p 2173 (2020)
Green tea contains a variety of biologically active constituents that are widely used in the pharmaceutical and food industries. Among them, simple catechins constitute a major group of compounds that is primarily responsible for the high biologic ac
Autor:
Ewelina Gumbarewicz, Jarogniew Luszczki, Anna Wawruszak, Magdalena Dmoszynska-Graniczka, Aneta Grabarska, Agata Jarząb, Krzysztof Polberg, Andrzej Stepulak
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Medical University of Lublin
Europe PubMed Central
Medical University of Lublin
Histone deacetylase inhibitors (HDIs) are a new class of drugs which affect the activity of HDACs resulting in changed of acetylation in many proteins. HDIs can induce differentiation, cell growth arrest, apoptosis, inhibit proliferation and angiogen