Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ewelina Dratkiewicz"'
Autor:
Justyna Mazurkiewicz, Aleksandra Simiczyjew, Ewelina Dratkiewicz, Magdalena Kot, Katarzyna Pietraszek-Gremplewicz, Dominika Wilk, Marcin Ziętek, Rafał Matkowski, Dorota Nowak
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract Background Keratinocytes constitute a major part of the melanoma microenvironment, considering their protective role towards melanocytes in physiological conditions. However, their interactions with tumor cells following melanomagenesis are
Externí odkaz:
https://doaj.org/article/2117950ab02546d4a09a257a9f23b444
Autor:
Justyna Mazurkiewicz, Aleksandra Simiczyjew, Ewelina Dratkiewicz, Katarzyna Pietraszek-Gremplewicz, Michał Majkowski, Magdalena Kot, Marcin Ziętek, Rafał Matkowski, Dorota Nowak
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-19 (2022)
Abstract Background The tumor microenvironment consists of stromal cells, extracellular matrix, and physicochemical properties (e.g., oxygenation, acidification). An important element of the tumor niche are cancer-associated fibroblasts (CAFs). They
Externí odkaz:
https://doaj.org/article/733b066595ca4df8a82fbd54927c4b6c
Autor:
Aleksandra Simiczyjew, Katarzyna Pietraszek-Gremplewicz, Ewelina Dratkiewicz, Marta Podgórska, Rafał Matkowski, Marcin Ziętek, Dorota Nowak
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
We have previously shown that combination of foretinib, an inhibitor of MET (hepatocyte growth factor receptor), with gefitinib or lapatinib, inhibitors of EGFR (epidermal growth factor receptor), has a synergistic cytotoxic effect on melanoma cells.
Externí odkaz:
https://doaj.org/article/9a79aeabf5a847aa823872ef9c071734
Autor:
Ewelina Dratkiewicz, Aleksandra Simiczyjew, Justyna Mazurkiewicz, Marcin Ziętek, Rafał Matkowski, Dorota Nowak
Publikováno v:
Cells, Vol 10, Iss 4, p 862 (2021)
Hypoxia and elevated extracellular acidification are prevalent features of solid tumors and they are often shown to facilitate cancer progression and drug resistance. In this review, we have compiled recent and most relevant research pertaining to th
Externí odkaz:
https://doaj.org/article/4418a591db5a4b81be9297cbcc1b2efe
Autor:
Piotr Kupczyk, Aleksandra Simiczyjew, Jakub Marczuk, Ewelina Dratkiewicz, Artur Beberok, Jakub Rok, Malgorzata Pieniazek, Przemyslaw Biecek, Dmitry Nevozhay, Bartosz Slowikowski, Grzegorz Chodaczek, Dorota Wrzesniok, Dorota Nowak, Piotr Donizy
Publikováno v:
Cells, Vol 10, Iss 2, p 286 (2021)
(1) Background: Poly(ADP-ribose) polymerase 1) (PARP1) is a pleiotropic enzyme involved in several cellular processes, e.g., DNA damage repair, regulation of mitosis, and immune response. Little is known about the role of PARP1 in melanoma developmen
Externí odkaz:
https://doaj.org/article/ca5ec85182c14a6f8745545aabec24c2
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173709 (2017)
Amoeboid movement is characteristic for rounded cells, which do not form strong adhesion contacts with the ECM and use blebs as migratory protrusions. It is well known that actin is the main component of mature forms of these structures, but the exac
Externí odkaz:
https://doaj.org/article/5f592e6ea2be4b5e9dd868de1306bafa
Autor:
Justyna Mazurkiewicz, Aleksandra Simiczyjew, Ewelina Dratkiewicz, Katarzyna Pietraszek-Gremplewicz, Michał Majkowski, Magdalena Kot, Marcin Ziętek, Rafał Matkowski, Dorota Nowak
Publikováno v:
Cell communication and signaling : CCS. 20(1)
BackgroundThe tumor microenvironment consists of stromal cells, extracellular matrix, and physicochemical properties (e.g., oxygenation, acidification). An important element of the tumor niche are cancer-associated fibroblasts (CAFs). They may consti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6691e8590cf81c1a131483ca4a914e65
https://pubmed.ncbi.nlm.nih.gov/35538545
https://pubmed.ncbi.nlm.nih.gov/35538545
Autor:
Dorota Nowak, Marta Podgórska, Ewelina Dratkiewicz, Marcin Ziętek, Katarzyna Pietraszek-Gremplewicz, Rafal Matkowski, Aleksandra Simiczyjew, Ilona Styczeń
Publikováno v:
Journal of Cellular and Molecular Medicine
Epidermal and hepatocyte growth factors can stimulate invasive abilities of melanoma cells, while treatment with combination of their receptors' (EGFR and MET, respectively) inhibitors reduces viability of these cells, as we have previously shown. Pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad111e26db4c305fdc47c3e07ffc8948
https://doi.org/10.1111/jcmm.14730
https://doi.org/10.1111/jcmm.14730
Autor:
Dorota Nowak, Rafal Matkowski, Aleksandra Simiczyjew, Ewelina Dratkiewicz, Justyna Mazurkiewicz, Marcin Ziętek
Publikováno v:
Cells, Vol 10, Iss 862, p 862 (2021)
Cells
Cells
Hypoxia and elevated extracellular acidification are prevalent features of solid tumors and they are often shown to facilitate cancer progression and drug resistance. In this review, we have compiled recent and most relevant research pertaining to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::981d798fbc4ec6c7467267ef1b9e2e6a
https://www.mdpi.com/2073-4409/10/4/862
https://www.mdpi.com/2073-4409/10/4/862
Autor:
Jakub Marczuk, Ewelina Dratkiewicz, Dorota Nowak, Aleksandra Simiczyjew, Dmitry Nevozhay, Piotr Kupczyk, Jakub Rok, Piotr Donizy, Przemyslaw Biecek, Bartosz Kazimierz Słowikowski, Grzegorz Chodaczek, Dorota Wrzesniok, Artur Beberok, Malgorzata Pieniazek
Publikováno v:
Cells
Volume 10
Issue 2
Cells, Vol 10, Iss 286, p 286 (2021)
Volume 10
Issue 2
Cells, Vol 10, Iss 286, p 286 (2021)
(1) Background: Poly(ADP-ribose) polymerase 1) (PARP1) is a pleiotropic enzyme involved in several cellular processes, e.g., DNA damage repair, regulation of mitosis, and immune response. Little is known about the role of PARP1 in melanoma developmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc8cd3ff0b13a98b6886e3b1f8c350d8
http://europepmc.org/articles/PMC7911865
http://europepmc.org/articles/PMC7911865