Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ewelina Betleja"'
Publikováno v:
eLife, Vol 7 (2018)
The two centrioles of the centrosome in quiescent cells are inherently asymmetric structures that differ in age, morphology and function. How these asymmetric properties are established and maintained during quiescence remains unknown. Here, we show
Externí odkaz:
https://doaj.org/article/367da7e2caf44df0bdabb4d4f66e45b6
Autor:
Durga Praveen Meka, Oliver Kobler, Shuai Hong, Carina Meta Friedrich, Souhaila Wuesthoff, Melad Henis, Birgit Schwanke, Christoph Krisp, Nessa Schmuelling, René Rueter, Tabitha Ruecker, Ewelina Betleja, Tao Cheng, Moe R. Mahjoub, Peter Soba, Hartmut Schlüter, Eugenio F. Fornasiero, Froylan Calderon de Anda
Publikováno v:
Cell reports, 39(3):110686
Microtubule (MT) modifications are critical during axon development, with stable MTs populating the axon. How these modifications are spatially coordinated is unclear. Here, via high-resolution microscopy, we show that early developing neurons have f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101ff667e2b17b630a49996d9ddd08c6
https://pubmed.ncbi.nlm.nih.gov/35443171
https://pubmed.ncbi.nlm.nih.gov/35443171
Autor:
Moe R. Mahjoub, Sarah Amalraj, Ewelina Betleja, Mustafa K. Khokha, Ann L. Miller, John R. Yates, James J. Moresco, Rachel E. Stephenson, Saurabh S. Kulkarni
SUMMARYMutations in CCDC11 have been identified in multiple patients with heterotaxy (Htx), a disorder of left-right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560c9e57b481da1410127e446a8fdae4
https://doi.org/10.1101/452631
https://doi.org/10.1101/452631
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
The two centrioles of the centrosome in quiescent cells are inherently asymmetric structures that differ in age, morphology and function. How these asymmetric properties are established and maintained during quiescence remains unknown. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b158d12ca367270e6fdb0b33889a4c32
https://elifesciences.org/articles/35439
https://elifesciences.org/articles/35439
Autor:
Chloe Potter, Didier Hodzic, Philip A. Ruzycki, Alexander V. Kolesnikov, Moe R. Mahjoub, Teresa A. Doggett, Ewelina Betleja, David Razafsky, Wanqiu Zhu, Vladimir J. Kefalov
Publikováno v:
Current biology : CB. 27(13)
Summary SYNE1 (synaptic nuclear envelope 1) encodes multiple isoforms of Nesprin1 (nuclear envelope spectrin 1) that associate with the nuclear envelope (NE) through a C-terminal KASH (Klarsicht/Anc1/Syne homology) domain (Figure 1A) [1–4]. This do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1cc57dd100d40a45d16b038dc9b9ab
https://pubmed.ncbi.nlm.nih.gov/28625779
https://pubmed.ncbi.nlm.nih.gov/28625779
Autor:
Moe R. Mahjoub, Ewelina Betleja, Emily John, Erica Silva, Philip C. Spear, Brian J. Mitchell, Siwei Zhang, James J. Moresco, John R. Yates
Publikováno v:
Molecular Biology of the Cell
Mutations in CCDC11 cause aberrant placement of internal organs and congenital heart disease in humans. Ccdc11 is a novel component of centriolar satellites and plays a critical role in motile and sensory ciliogenesis. The results implicate centriola
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dd4bffa6ddfc000d183277c1b3be91d
https://pubmed.ncbi.nlm.nih.gov/26538025
https://pubmed.ncbi.nlm.nih.gov/26538025
Autor:
Ewelina Betleja, Douglas G. Cole
Publikováno v:
Current biology : CB. 20(21)
SummaryA recent study reveals that the large coiled-coil protein CEP290 is an integral component of the transition zone between the cell body and the cilium and functions as a gatekeeper to regulate trafficking of ciliary proteins.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f256fb24ed24883757e0d51c39538f
https://pubmed.ncbi.nlm.nih.gov/21056833
https://pubmed.ncbi.nlm.nih.gov/21056833
Publikováno v:
Methods in cell biology. 93
Intraflagellar transport (IFT) is characterized by a robust bidirectional movement of large proteinaceous particles along the length of eukaryotic cilia and flagella. Essential for the assembly and function of the organelle, IFT is believed to transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6c89c5634d9d1fe8dccf55b3ddc8484
https://pubmed.ncbi.nlm.nih.gov/20409818
https://pubmed.ncbi.nlm.nih.gov/20409818
Publikováno v:
Methods in Cell Biology ISBN: 9780123813770
Intraflagellar transport (IFT) is characterized by a robust bidirectional movement of large proteinaceous particles along the length of eukaryotic cilia and flagella. Essential for the assembly and function of the organelle, IFT is believed to transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a269d4c7a7232a90a0f77444b0719a1
https://doi.org/10.1016/s0091-679x(08)93010-7
https://doi.org/10.1016/s0091-679x(08)93010-7